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Doctor insights on: Vital Signs Of Rheumatoid Arthritis With Negative Blood Tests

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Dr. Thomas Namey
2,400 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Can you have rheumatoid arthritis without it showing up in blood tests?

Can you have rheumatoid arthritis without it showing up in blood tests?

Arthritis: There are many types of arthritis, some of which are degenerative or post-traumatic. The other general kind of arthritis is inflammatory. The classification of type requires a history, examination, diagnostic x-rays, and if indicated, blood tests. Treatment is determined by type of arthritis. Not all patients with RA have positive blood tests. Occasionally, blood tests are done a few times. ...Read more

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How many blood tests are taken to test for rheumatoid arthritis?

How many blood tests are taken to test for rheumatoid arthritis?

Basic two: Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis. Other tests are done to measure inflammation, determine which drugs may be used, etc. Note: the rf and ccp only help confirm the diagnosis. The presence of an antibody does not definitively make the diagnosis. Also, persons may have RA and be rf and ccp negative. ...Read more

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How many different blood tests are there for rheumatoid arthritis?

How many different blood tests are there for rheumatoid arthritis?

Dx and activity: Screening tests for rheumatoid arthritis are acpa (anti-citrullinated protein antibodies) and rheumatoid factor. The activity of the disease may be monitored by ESR and CRP tests. Blood tests alone are not sufficient for the diagnosis, history and clinical examination are essential. ...Read more

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I've had pain in my joints, I got blood tests related to autoimmune diseases I got a positive ANA and anti-rnp, is this found in rheumatoid arthritis?

I've had pain in my joints, I got blood tests related to autoimmune diseases I got a positive ANA and anti-rnp, is this found in rheumatoid arthritis?

Possible: You should ask your rheumatologist. ANA and anti-RNP are seeing in mixed connective tissue disease and can overlap with rheumatoid arthritis but more information is needed, talk to your rheumatologist about them. RA by itself usually have other 2 antibodies positive called RF ( rheumatoid factor) and anti-CCP ( citrullinated peptides). ...Read more

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I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

Tests are accurate: If you have the right tests theses are quite accurate.You should discuss with your doctor who ordered the tests, because he knows your clinical history and will be able to explain the results to you.I can not answer without knowing the tests which were done. ...Read more

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Is it possible to have little to no swelling with rheumatoid arthritis? Also, can your blood test negative and then be positive later?

Is it possible to have little to no swelling with rheumatoid arthritis? Also, can your blood test negative and then be positive  later?

Yes: Yes, there can be periods of increased as well as decreased synovial & soft tissue activity. Some immune testing may be more sensitive than others, with results varying with time as well. ...Read more

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How often should one be tested for rheumatoid arthritis after negative test, though having symptoms?

How often should one be tested for rheumatoid arthritis after negative test, though having symptoms?

Arthritis: There are negative test and there are additional tests that may be followed for a now symptomatic person with rheumatoid or infalmmatory as much as at a certain level. Talk to your doctor about this especially if you are taking medications. ...Read more

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Can you still have rheumatoid arthritis with a negative rheumatoid factor test?

Can you still have rheumatoid arthritis with a negative rheumatoid factor test?

Yes: While the vast majority of patients with RA have a positive rf, a certain percentage do not. Typically, the younger the patient, the better the chance the rf may be negative, depsite a clinical diagnosis of ra. ...Read more

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What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

Need more testing: ANA is a screening test. A positive result only indicates more testing might be needed. The speckled portion of the result is not very helpful on its own. About 5% of humans (1 in 20) have a positive ANA for no reason. ...Read more

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My ESR is 34, rf, aso &ana tests all are negative. I have joint pain in my finger, knee & toe. Mild swelling in 3 fingers at dip joint. Can i still have rheumatoid arthritis?

My ESR is 34, rf, aso &ana tests all are negative. I have joint pain in my finger, knee & toe. Mild swelling in 3 fingers at dip joint. Can i still have rheumatoid arthritis?

Possible: It is possible to have sero- negative ra, in which the rheumatoid factor assay is negative. It is also possible that you have another autoimmune illness, there are some overlaps in these conditions and the lab work doesn't always give an exact diagnosis. You should see a rheumatologist if your joint inflammation persists. ...Read more

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How is it possible for someone to have rheumatoid arthritis with a negative rheumatoid factor?

How is it possible for someone to have rheumatoid arthritis with a negative rheumatoid factor?

Great question!: Rheumatoid arthritis (RA) is a disease that generally causes stiffness, swelling, and pain of the small joints of the body (wrists, fingers) in a symmetric manner. For the majority of patients with RA, rheumatoid factor and anti-CCP antibodies are found in the blood. However, these tests are not required to make the diagnosis if there are other findings on exam that are consistent with RA. ...Read more

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How do I know if I have rheumatoid arthritis without blood test?

How do I know if I have rheumatoid arthritis without blood test?

Arthritis: There are many types of arthritis, some of which are degenerative or post-traumatic. The other general kind of arthritis is inflammatory. The classification of type requires a history, examination, diagnostic x-rays, and if indicated, blood tests. Treatment is determined by type of arthritis.. ...Read more

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How do doctors test for rheumatoid arthritis?

How do doctors test for rheumatoid arthritis?

Exam history and lab: you need to have a history taken, a family history, examination and then different blood tests like rheumatoid factor CRP Sed rate ANA etc It takes all of the above items to make a diagnosis ...Read more

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Dr. Debra Rosenblatt
40 doctors shared insights

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more


Dr. Robert Lowe
1,537 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more