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Doctor insights on: Vital Signs Of Rheumatoid Arthritis With Negative Blood Tests

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Dr. Thomas Namey
2,350 doctors shared insights

Arthritis (Definition)

Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Can you have rheumatoid arthritis without it showing up in blood tests?

Can you have rheumatoid arthritis without it showing up in blood tests?

Arthritis: There are many types of arthritis, some of which are degenerative or post-traumatic. The other general kind of arthritis is inflammatory. The classification of type requires a history, examination, diagnostic x-rays, and if indicated, blood tests. Treatment is determined by type of arthritis. Not all patients with RA have positive blood tests. Occasionally, blood tests are done a few times. ...Read more

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How many blood tests are taken to test for rheumatoid arthritis?

How many blood tests are taken to test for rheumatoid arthritis?

Basic two: Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis. Other tests are done to measure inflammation, determine which drugs may be used, etc. Note: the rf and ccp only help confirm the diagnosis. The presence of an antibody does not definitively make the diagnosis. Also, persons may have RA and be rf and ccp negative. ...Read more

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How many different blood tests are there for rheumatoid arthritis?

How many different blood tests are there for rheumatoid arthritis?

Dx and activity: Screening tests for rheumatoid arthritis are acpa (anti-citrullinated protein antibodies) and rheumatoid factor. The activity of the disease may be monitored by ESR and CRP tests. Blood tests alone are not sufficient for the diagnosis, history and clinical examination are essential. ...Read more

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I've had pain in my joints, I got blood tests related to autoimmune diseases I got a positive ANA and anti-rnp, is this found in rheumatoid arthritis?

I've had pain in my joints, I got blood tests related to autoimmune diseases I got a positive ANA and anti-rnp, is this found in rheumatoid arthritis?

Possible: You should ask your rheumatologist. ANA and anti-RNP are seeing in mixed connective tissue disease and can overlap with rheumatoid arthritis but more information is needed, talk to your rheumatologist about them. RA by itself usually have other 2 antibodies positive called RF ( rheumatoid factor) and anti-CCP ( citrullinated peptides). ...Read more

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I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

Not accurate for dz: Adding to other answer: so i'm assuming you are ana-positive and rf-negative. ANA is used to screen for lupus and other connective tissue diseases. Everyone with lupus has a positive ana, but not everyone with a positive ANA has lupus. Up to 33% of healthy people without lupus has a positive ana. That's a huge number. So there are many more people with a positive ANA without lupus than have lupus. ...Read more

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Is it possible to have little to no swelling with rheumatoid arthritis? Also, can your blood test negative and then be positive later?

Is it possible to have little to no swelling with rheumatoid arthritis? Also, can your blood test negative and then be positive  later?

Yes: Yes, there can be periods of increased as well as decreased synovial & soft tissue activity. Some immune testing may be more sensitive than others, with results varying with time as well. ...Read more

Dr. Ronald Krauser
1 doctor shared a insight

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more


Dr. Robert Lowe
1,459 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more