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Doctor insights on: Viracept Protease Inhibitor

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How does a protease inhibitor work to treat hiv?

How does a protease inhibitor work to treat hiv?

Enzyme inhibitor: Protease is an enzyme used by the virus in its multiplication sequences of events. Inhibition of this protease makes it more difficult for the virus to multiply in the infected cell. ...Read more

Dr. Ana Adelstein
2 doctors shared insights

Viracept (Definition)

Viracept is a protease inhibitor which is a kind of drug used for HIV (anti-viral ...Read more


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Can you tell me about hiv-1 protease inhibitor?

Can you tell me about hiv-1 protease inhibitor?

See below: Please consult this site for information on this topic. http://www.webmd.com/hiv-aids/protease-inhibitors-pis-for-hiv ...Read more

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\should I be worried about taking protease inhibitors?

\should I be worried about taking protease inhibitors?

Why?: If you have HIV disease this class of compounds is one of the mainstays of therapy, and the side-effects are overwhelming outweighed by the benefits. ...Read more

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Is there HIV drug resistance to protease inhibitors?

Is there HIV drug resistance to protease inhibitors?

Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more

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Does viracept (nelfinavir) work well ?

Does viracept (nelfinavir) work well ?

Yes: Viracept (nelfinavir) is an effective protease inhibitor used in combination with other anti-viral medications to treat hiv. It is not commonly used anymore because newer drugs require less pills and have less side effects. ...Read more

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If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more

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What are inhibitors? What is the normal level in our body?

Question unclear: Inhibitors of what? Substances which are inhibitors block a physiologic pathway and often there is a balance between stimulators and inhibitors which shifts with body needs. There are also numerous medications which inhibit physiologic or pathophysiological functions. ...Read more

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What are the cox-1 and cox-2 inhibitors? Are they pain blockers?

What are the cox-1 and cox-2 inhibitors?  Are they pain blockers?

No and Yes: Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys. Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker. ...Read more

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Can you tell me examples of enzyme inhibitors?

Can you tell me examples of enzyme inhibitors?

Viagra (sildenafil) !: Sildenafil (Viagra), a common treatment for male erectile dysfunction is a potent inhibitor of cGMP specific phosphodiesterase type 5, the enzyme that degrades the signalling molecule cyclic guanosine monophosphate. ...Read more

Dr. Michael Kleerekoper
7 doctors shared insights

Protease Inhibitor (Definition)

Protease inhibitors are a kind of drug used for HIV (anti-viral ...Read more