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Doctor insights on: Vip Chemotherapy

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

Dr. Devon Webster
972 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Chemotherapy hormone receptor positive node breast cancer?

Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Why etoposide administered before ifosfamide in chemotherapy ?

Why etoposide administered before ifosfamide in chemotherapy ?

NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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Rise in psa after radiation and hormone treatment?

Not enough info: You describe a complex situation that requires complete review of the medical record. Questions that need to be answered include: - cancer grade - psa at diagnosis - rate of psa rise - stage, ?Mets? - duration of hormones - how long since radiation... See your urologist or radiation oncologist and ask them all of your questions. If you don't feel comfortable with them, seek another opinion. ...Read more

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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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Breast cancer chemotherapy in hepatitis b patients?

Breast cancer chemotherapy in hepatitis b patients?

Challenging : Appropriate involvement of hepatologist and treatment (or prophylaxis) of hep b is imperative. ...Read more

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How effective r chemotherapy uft pills in metastic colon cancer?

How effective r chemotherapy uft pills in metastic colon cancer?

Some response: meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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Hormone therapy for prostate cancer?

Hormone therapy for prostate cancer?

Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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What about neuroendocrine (islet cell tumors)?

What about neuroendocrine (islet cell tumors)?

Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read more

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Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read more

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For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

Not a standard treat: Cytoxan (cyclophosphamide) and 5-fu jused to be used as first line chemo for breast cancer, but there are much more effacious drugs available now. I would not use these drugs now as first line treatment fofr anything except in special circumstances. ...Read more

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What is adjuvant chemo?

What is adjuvant chemo?

Adjuvant chemo: Adjuvant chemo is chemotherapy that is given after curative surgical resection of a cancer. It is given to reduce risk of recurrence of cancer. ...Read more

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Can Radiotherapy be used for metastic colon cancer if chemotherapy is resistant ?

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Radiotherapy be used for metastic colon cancer if chemotherapy is resistant ?

Not often: Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. ...Read more

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Are cea markers reliable for metastic colon cancer ?

Are cea markers reliable for metastic colon cancer ?

Depending how used: CEA first identified in 1965 by Phil Gold and Samuel O. Freedman in human colon cancer extracts. Thought to be valuable for dx colorectal Ca but the glycoprotein is also expressed in inflamed tissue so that smoking and enema can cause rise. Best used for monitoring so that if present in primary and rises it represents treatment failure and if diminishes during treatment it represents a response. ...Read more

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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