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Doctor insights on: Vidaza Neutrophils

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Is it risky to take vidaza if I have a low neutrophil count? Thank u

Is it risky to take vidaza if I have a low neutrophil count? Thank u

See details: Dosage adjustments are made if white counts, platelets, etc. Are too low. Whether the dose should be lowered or the drug stopped temporarily is up to the doctor treating you. ...Read more

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My dad has MDS and getting his 5th cycle if Vidaza. Hb up by 3 to reach 12, and platelets now 160. But causing very low neutrophil. Solution?

Seek guidance from y: Your dad's oncologist can address this issue and explain it. Please send us report of his neutrophil counts. If it is >500, that is considered safe. It is only worrysome if the total count is 100 or lower...then there is risk of Infection (Fever is the sign of infection).
His neutrophil counts will start recovering just like his Hb and platelets have. He may need Vidaza dose reduction. Neupogen ...Read more

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How long does it take for vidaza side effects (if any) to show?

Acute and delayed: Vidaza is well tolerated. But there can be mild nausea during chemo. Later on and for 2-4 weeks, blood counts go down causing anemia (low hemoglobin), and low WBC counts and low platelets. So patients need their blood counts checked frequently (once or twice weekly is common schedule) sometimes even daily counts required, if platelet counts drop below 30, 000. ...Read more

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Starting vidaza soon. Any advice? Should I be scared? Worried?

It is one treatment: This is one option of treatment for mds. It is not a difficult treatment, yet the disease is difficult to manage and control for too long. Good luck. ...Read more

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What is the duration of severe neutropenia after Vidaza Treatment for MdS? Last vidaza Cycle ended 20 days ago. GSf given but no response yet.

4-6 weeks: Vidaza can cause prolonged neutropenia which can be followed by remission and recovery of neutrophils....but you need to give yourself 1 to 2 more weeks. On the other hand blood counts can remain very low if the MDS is resistant to Vidaza in which case there may not be any recovery of Neutrophils. A Bone marrow exam can help to differentiate these 2 possibilities and help in deciding the next step ...Read more

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What are the most recent treatments for Intermediate risk MDS in elderly other than Vidaza & Revilmid? Any new treatment will be available soon?

Yes there are others: A good hematologist is the first requirement to treat MDS properly as there are several sub types of disease. Depending on which cell in the blood is impaired, a targeted drug can be selected to treat him. There are some drugs targeted for red cells (Anemia) and others for low WBC and low platelet counts. The 3rd approved drug to treat MDS is: Decitabine (Dacogen). ...Read more

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Taking 2 types of intravenous antibiotics. Took vidaza 20 days ago. Can I take solgar advanced 40+ acidophilus? How many capsules per day?

Taking 2 types of intravenous antibiotics. Took vidaza 20 days ago. Can I take solgar advanced 40+ acidophilus? How many capsules per day?

MDS and Bacteria: Solgar Advanced 40+ Acidophilus contains these bacteria: L. acidophilus, L. rhamnosus GG, L. paracasei, B lactis and S. thermophilus. In general, it is recommended that neutropenic and infected patients avoid introducing more bacteria into their system. There is no credible evidence that these bacteria improve clinical outcomes and could introduce harm. ...Read more

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Dad has MDS and on vidaza for since 4 months. Before treatment he needed 3 RBC units every 3 wks. Now 2 units in 5 wks. Is this partial response?

Dad has MDS and on vidaza for since 4 months. Before treatment he needed 3 RBC units every 3 wks. Now 2 units in 5 wks. Is this partial response?

Yes: A response is considered as a rise in hemoglobin of at least 1.5 g/dl sustained for 8 wks AND a reduction in the number of RBC units by at least 4 units over the current 8 wks compared to the previous 8 wks. Doing some proportional adjustment:He required approximately 8 units the previous 8 wks and the estimated units for the current period is 3 units. Assumming his hemoglobin rose at least 1.5g/ ...Read more

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How many days does it take to go out febrile neutropenia for 70 yrs old man treated by Vidaza for High Risk MDS? His ANC is zero, 20 days post vidaza

How many days does it take to go out febrile neutropenia for 70 yrs old man treated by Vidaza for High Risk MDS? His ANC is zero, 20 days post vidaza

Should be hospitalized: Febrile neutropenia is an emergency, hospitalization, isolation, broad spectrum antibiotics need to be given till recovery. Other treatments like G-CSF are given as per protocol for each institution, there may other problems causing delayed recovery from neutropenia, which would be assessed by treating team, good luck ...Read more

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Will their be new treatments for intermediate risk MDS in 2016? Other than Vidaza and supportive care? I care abt newest treatment for 70 yr patient

Myelodysplastic Syndromes: Common drugs for MDS include:1.Azacitidine (Vidaza) 2.Cytarabine (Cytosar-U) 3.Daunorubicin (Cerubidine) 4. Decitabine (Dacogen) 5. Idarubicin (Idamycin) 6.Lenalidomide (Revlimid).Overall, 30 to 40% of patients may benefit.
Gene manipulation of own stem cell has cured, patients with severe advanced leukemia, is the future. Pts. Reported rapidly to iv infusion, was recently reported ...Read more

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Elevated neutrophils and elevated hemoglobin?

Elevated neutrophils and elevated hemoglobin?

Maybe Infection.: The elevation of neutrophils coukl mean bacterial infection, as these cells are important in fighting this kind of infection. The high hemohlobin seems nonspecific, in abscence of other symptoms and signs. It could possibly mean a polycythemia, one of the porphorias, or a myeloproliferative disorder, which could explain the high neutrophils. It can also be from high altitude. See dr. For more. ...Read more

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Does appendicitis cause increased neutrophils?

Does appendicitis cause increased neutrophils?

Often yes.: Not invariably but there are instances in which an elevation in white count is seen in patient's with appendicitis. ...Read more

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What do low neutrophils and high lymph counts indicate?

What do low neutrophils and high lymph counts indicate?

High counts: This could represent a serious blood or bone marrow condition...Further evaluation is required preferably by a hematologist. ...Read more

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What does it mean to have a high abs neutrophils count?

What does it mean to have a high abs neutrophils count?

Usually an infection: The absolute neutrophil count is the product of the % neutrophils & total wbc. A high absolute neutrophil count is usually seen in many types of infections. Other causes are inflammatory conditions, stress, medications like steroids, lithium, injections like growth factors, cushing's disease and sometimes some forms of chronic leukemia or myeloproliferative disorders (blood disorder). ...Read more

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High neutrophil and high vpm, women means something????

High neutrophil and high vpm, women means something????

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual values for the test results. ...Read more

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What does it mean to have a high count of neutrophil bands?

What does it mean to have a high count of neutrophil bands?

Infection: This is usually indicative of acute bacterial infection. ...Read more

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I have an absolute neutrophil of 1354.... What does that mean?

I have an absolute neutrophil of 1354.... What does that mean?

Total number: This is the number of neutrophils in a standard volume of your blood. This count is lowish but probably not dangerous; your physician will want to keep an eye on it. If you're otherewise healthy I would not be concerned. ...Read more

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My count is 8300 up in two weeks fron 5400 absolute neutrophils?

My count is 8300 up in two weeks fron 5400 absolute neutrophils?

Normal flucctuation: WBC counts fluctuate from one day to the other. Tell us why you are getting it checked in the first place? If you have some illness or symptoms, you need to describe them in some detail, so that we can relate your symptoms to your blood counts. Both of your counts are normal right now. ...Read more

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Have a absolute neutrophil level of 8117. Should I be concerned?

Probably not: If you have had recent infection a stress from another illness have been on certain needs or are a heavy smoker may just be normal for you. ...Read more

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What does it mean if my monocytes are low and neutrophils are high?

What does it mean if my monocytes are low and neutrophils are high?

Relative v.absolute?: The percentages can be misleading. One must really look at the absolute amounts of both. Depending on the circumstances, a true absolute neutrophilia may be caused by a list of conditions too long to list here. In most cases, the low monocyte count is due to the relative expansion of neutrophils (infections, smoking, trauma, autoimmune conditions, even some cancers). Your md should be able to help. ...Read more

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What does low neutrophils and high lymphcytes indicate? With low hb?

What does low neutrophils and high lymphcytes indicate? With low hb?

It depends: A HGB less than 10.5 in a female or 11.5 in a male may be important. One cannot look just at lynphocyte and neutrophil percentages. It must be interpreted in the context of the total white blood cell count. ...Read more

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I have a white count of 15, neutrophils are 9 and basphils are. 11, rest all ok?

Leukocytosis is...: ...an increase in the total number of WBCs due to any cause. From a practical standpoint, it is often sub-classified according to the component of white cells that contribute to an increase in the total number of WBCs. Context is important here--e.g. why did they test you? Read more at: http://emedicine. Medscape. Com/article/956278-overview ...Read more

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What might cause elevated absolute neutrophils but normal neutrophil percentage?

What might cause elevated absolute neutrophils but normal neutrophil percentage?

TheTruthOnAbsolute: Percentages are relative numbers. You could have one billion neutrophils (elevated) but only 10% of total White Cells (low, %, based on normal ranges), but 10% of one billion is sky high. We are always looking at relative numbers and absolute numbers. Relative numbers like % can be manipulated in various ways, good and bad, but absolute numbers are the nitty-gritty. ...Read more

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If your neutrophils get low during a long bout of giardia, can they rebound later?

If your neutrophils get low during a long bout of giardia, can they rebound later?

It is very: Likely. If the dip us related to the infection or it's treatment it is going to improve as things resolve. ...Read more

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What is the definition or description of: wright smear of lesion shows neutrophils?

What is the definition or description of: wright smear of lesion shows neutrophils?

Histologic stain: Wright's stain is a histologic stain that facilitates the differentiation of blood cell types. It is used primarily to stain peripheral blood smears and bone marrow aspirates which are examined under a light microscope. In cytogenetics it is used to stain chromosomes to facilitate diagnosis of syndromes and diseases.
It is named for james homer wright, who devised the stain. ...Read more