Top 20 Doctor insights on: Vicodin and amitriptyline
I have MS and trigem neuralgia and have terrible pain. Tried gaba, baclofen, norco, (hydrocodone and acetaminophen) elavil, tegretol, otc, etc...What is the best pain med for this?
Trigeminal neuralgia: Sadly trigeminal neuralgia is a poorly understood disease that has an even worse track record for treatment. Most patients suffer from this disease without much relief. There is a growing body of evidence looking into Lamotrigine as a treatment. Ask your prescribing doctor if this is an alternative. ...Read moreSee 3 more doctor answers
I've asked a lot: Of MD's this question. Some start you off on the new med right after stopping the old one. Some wait as much as two weeks. You are mixing an herb with a Tricyclic, so I'd play it safe and wait awhile. As a psychiatrist who knows about herbs. Most don't. ...Read more
Worth a try: Complex regional pain syndrome is a challenging problem to treat, and your doctors will be trying a number of options to help you. Amitriptylene at low dose may have some positive effects in pain syndromes. If you're not already working with a pain medicine specialist on this problem, you might consider a consultation. ...Read more
Many: In that it affects multiple neurotransmitters, it can cause many side effects. Receptors and side effect: histamine - sedation, weight gain; cholinergic - dryness, urinary retention, memory decline, ed; adrenergic - low blood pressure, tremor, rapid heart rate; serotonin - tiredness, weight gain, ed. ...Read more
Proceed With Caution: Using Elavil (generic amitriptyline) with nulev (generic hyoscyamine) may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heart beats, confusion, and memory problems. The elderly are especially vulnerable to these side effects. Work closely with md. ...Read more
We used to think that amitriptyline acted on the brain at the level of the thalamus or other pain interpretive centers but recent evidence points to a peripheral action site blocking C-type pain fibers- specifically, nicotinic acetylcholine receptors carrying neuropathic pain.
More cool (and PRACTICAL) stuff if you want to talk about it:
www. Healthtap. Com/drsaghafi ...Read more
Elavil (amitriptyline) effects: Amitriptyline is the generic form of elavil (amitriptyline). It is a tricyclic antidepressant medication that has anticholinergic activity. I am not sure what effect you are having but urinary retention can occur. Discuss in detail with your prescribing health professional any difficulties you are experiencing. ...Read more