verapamil gel for peyronie disease

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2 Answers
Dr. Alvin B. Lin answered:

dear doctor, i suffering peyronie's disease last 1& 1/2 year. is verapamil gel effective & is this gel available in india. thanks.?

Depends . . .

Verapamil_hydrochloride
Published peer-reviewed randomized controlled trials re treatment of Peyronie's suggest intralesional injection of verapamil might work. Check out http://www.nature.com/ijir/journal/v15/n5s/pdf/3901084a.pdf - they didn't recommend topical verapamil in 2003. Check out http://www.nature.com/ijir/journal/v24/n1/pdf/ijir201145a.pdf in which no conclusive benefit to any single therapy in early 2012.
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Does verapamil gel work to reduce size of plantar fibromatosis?

Yes

But it may take several months
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Dr. Tonga Nfor answered:

Can u pls adv if its ok to use verapamil gel? I have a high ggt liver count?

Caution

Liver
Liver disease could cause a high GGT level. Caution is advised when taking verapamil in the presence of liver disease. Your doctor should guide you.
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Dr. Howard R. Fox answered:

I am needing the best treatment for plantar fibromatosis. i work 12 hr. shifts in a hospital as a cna/tech/pca, i have seen 2 podiatrists and am trying to figure out the best treatment plan. At first i was told transdermal verapamil 15% gel but then found

Plantar

Plantar fibromatosis is a difficult problem to treat. Fortunately, most people with this don't have symptoms. We're not really sure why some people get this, but it seems to be associated with trauma to the area, and, in some cases, patients on phenytoin (Dilantin) can develop lesions. Those with systemic conditions such as epilepsy, alcoholism, liver cirrhosis, hypothyroidism and diabetes mellitus may have an increased incidence of plantar fibromas. Conservative treatment involves anti-inflammatory medication, steroid injections, dispersion padding to the area or the use of some kind of innersole to keep pressure off the area, and physical therapy. I have never heard of using radio frequency ablation (RFA) for this problem, and "plasma injections" are a scam in my opinion, and there is no documented proof it does anything beyond making the doctor's wallet fatter. Do not even remotely consider surgery unless you've exhausted all (legitimate) conservative options and you're miserable. Finally, it's important, with any soft tissue mass, to be absolutely certain you're dealing with a plantar fibroma, and not something more serious. I assume, given that you've already seen two podiatrists for this, you've been worked up to make sure we're certain it's plantar fibromatosis.
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Dr. David Geffner answered:

Is there any cure for peyronie disease?

No

Urologist
See a urologist who may be able to improve it.
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Are there treatments for peyronie disease?

No way

Urologist
When minor can be helped or corrected in some with oral Potaba, in others with surgery, but never with a penile pump or any home remedies. Best to consult with a urologist
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Is there a home remedy for peyronie disease?

No way

Urologist
When minor can be helped or corrected in some with oral Potaba, in others with surgery, but never with a penile pump or any home remedies. Best to consult with a urologist
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Can peyronie disease be corrected with pump?

No way

Urologist
When minor can be helped or corrected in some with oral Potaba, in others with surgery, but never with a penile pump or any home remedies. Best to consult with a urologist
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Are there any treatments for peyronie disease?

Yes.

Open-uri20120915-24710-17hnwep
Peyronie's disease is scarring of the tunica albicans of the penile shaft. It is inflammatory and is analagous to Dupuytren's contracture of the palmar fascia if the hand. Steroid injections may help, and there is surgery in the background. The FDA has approved a "collagenolytic enzyme" for the hand and it has been used successfully for Peyronie's without a formal indication.
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Are there any home remedy for peyronie disease?

No

Local treatment with oitment,injection,surgery may be helpful.Talk to yor PCP/Urologist
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