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Doctor insights on: Vasoactive Intestinal Polypeptide

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What's vasoactive intestinal polypeptide vip?

What's vasoactive intestinal polypeptide vip?

VIP definition: Vasoactive intestinal peptide or vip is a peptide hormone containing 28 Amino Acid residues. Vip is produced in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain. Vip stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea & stomach. ...Read more

Intestine (Definition)

The gastrointestinal tract starts at the mouth, travel down the tunnel (esophagus), which connects to the stomach, which then empties into the duodenum, jejunum, and ileum---the three parts of the small intestine (@25 feet). This empties into the colon or large intestine (about 5 feet), which then becomes the sigmoid colon, rectum and out the anus. So, every morsel eaten ...Read more


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What's vasoactive intestinal polypeptide vip?

VIP definition: Vasoactive intestinal peptide or vip is a peptide hormone containing 28 Amino Acid residues. Vip is produced in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain. Vip stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea & stomach. ...Read more

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What does vasoactive intestinal peptide do?

What does  vasoactive intestinal peptide do?

Messenger proteins: These proteins are released by nerve endings in the intestines. They can cause the muscle walls of organs and blood vessels to relax . For example, they help the muscle band in the lower esophagus to open up and pass food into the stomach, and can increase blood flow in the intestines. They also stimulate secretions. Tumors that produce large amounts of vip cause severe diarrhea. ...Read more

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Does vip (vasoactive intestinal peptides) have to be out on ice imediately. If done incorrect would you get false high or low?

Does vip (vasoactive intestinal peptides) have to be out on ice imediately. If done incorrect would you get false high or low?

If it's going to be: Stored it needs to be kept on ice then frozen. However, once the blood is drawn, it is always better for it to be put on ice. What actually disturbs the results, could be the technique used in the washing, essentially the "lab" section. Most of the time the lab techs have done this for years and are capable of producing good results. If you are not satisfied, have it repeated. ...Read more

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How high must vasoactive intestinal levels be to indicate a disease process?

How high must vasoactive intestinal levels be to indicate a disease process?

>75: The diagnosis of a vipoma is established by the presence of an otherwise unexplained high volume secretory diarrhea and a serum vip concentration in excess of 75 pg/ml. A single elevated vip level should be confirmed by additional testing. ...Read more

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Elevated vasoactive intestinal peptides chromogranin & 5-hiaa. Could these tests be linked? Or is one incorrect. Hypokalemia and dehydration.

Elevated vasoactive intestinal peptides chromogranin & 5-hiaa. Could these tests be linked? Or is one incorrect. Hypokalemia and dehydration.

Can be linked: Neuroendocrine tumor in the intestine can produce all these abnormalities. Such tumors may be small and non-malignant but can still cause considerable morbidity. It may require you to consult both a GI specialist and an endocrinologist to sort things out. ...Read more

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Can GI issues cause hypokalemia and false positive Chromogranin and vasoactive intestinal peptides ? One high reading one regular reading for both.

Can GI issues cause hypokalemia and false positive Chromogranin and vasoactive intestinal peptides ?  One high reading one regular reading for both.

Depends: GI issues can cause hypokalemia like diarrhea or vomiting. False positives for chromogranin A can be related to PPI use like omeprazole, as can pernicious anemia, kidney and/or liver issues. False positive VIP levels can be from fasting, small bowel surgeries, and kidney disease but also elevated in inflammatory bowel disease. ...Read more

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Is insulin a polypeptide or a protein?

Is insulin a polypeptide or a protein?

Definition: Hi. A definition was decided arbitrarily long ago, in the infancy of biochemistry, that proteins are 50 or more amino acids, and polypeptides are 49 or fewer. Insulin is a 51 amino acid polypeptide, and therefore, a protein. But it's completely arbitrary, and the chemistry of insulin doesn't care if you call it a protein or a polypeptide. But insulin rocks, eh?! ...Read more

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How accurate is pancreatic polypeptide In detecting pancreas tumor?

How accurate is pancreatic polypeptide
In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

Not much evidence: There aren't a lot of studies out that have tested the health effects of all these collegen supplements.One study found that it does not really help with bone health,and another showed some preservation of lean body mass in older women but no skin improvement.It seems that elastin skin products have not shown clinically to improve elasticity of the skin but do help the skin hold moisture. ...Read more

Vasoactive (Definition)

Any medication, naturally-occurring substance or anything else that makes little arteries (or perhaps other vessels) widen or narrow, controlling where the blood goes ...Read more


Bowel (Definition)

The bowel is the intestinal tract in the body. The small intestine ...Read more