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Doctor insights on: Uterine Dysplasia

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Biopsy showed "complex dysplasia with atypia" and a spot of cancer. Scared. Can you give any reassurance on this type of uterine cancer?

Biopsy showed "complex dysplasia with atypia" and a spot of cancer.  Scared.  Can you give any reassurance on this type of uterine cancer?

Full treatment now: It sounds like it was caught when it just crossed the line and would be able to hurt you. If you receive standard treatment how, it's most likely you'll get a cure. When i was a kid, we cured 2 out of 6 cancers; a med student 3 out of 6, now 4 out of six. Good luck.

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Uterus (Definition)

The uterus is a muscular organ in a woman's pelvis where the the fertilized egg attaches ...Read more


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Cervix, uterus, biopsy - Mild to moderate dysplasia ( HGSIL, CIN - I / II ) What does that mean?

Cervix, uterus, biopsy - Mild to moderate dysplasia ( HGSIL, CIN - I / II ) What does that mean?

Exposure to HPV: This means that you contracted the human papilloma virus via sexual intercourse likely within the last 2 years; it will likely heal on its own, but you want to get repeat pap smears in shorter time intervals until then. Being a cigarette smoker increases chances of this progressing to CIN III. Women with this condition need to be closely followed by a gynecologist.

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Had severe dysplasia (had leep) , now breakthough bleeding. Any connection with precancerous cells of the uterus and cervical dysplasia?

Had severe dysplasia (had leep) , now breakthough bleeding. Any connection with precancerous cells of the uterus and cervical dysplasia?

It is unlikely that: Your irregular bleeding is related to the leep or utrine cancer unless the leep was recently done and u r bleeding from there. Cervical cancer and uterine cancer are seperate phenomenon, though cervical cancer can extend into the uterus. Depending on age, uterine cancer is low on the list as a cause of the bleeding but see your doc if older than 35, may need endometrial biopsy just 2 b sure?

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I had cervical dysplasia, laser surgery more than 25 years ago. Intact overies, uterus. 69 y.O. Do I need pap tests, pelvic exams now? How often?

I had cervical dysplasia,  laser surgery more than 25 years ago. Intact overies, uterus. 69 y.O. Do I need pap tests, pelvic exams now? How often?

You can stop: Current acog and asccp guidelines recommend repeating pap smears yearly for the first 20 years for people that have been treated for moderate to severe cervical dysplasia. After that one should go to every 3 years if they have been normal and usually by age 70 pap smears are no longer needed. You should continue to have yearly exams and a pap smear if something looks abnormal thereafter.

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28 year-old woman was found during laparoscopy for endometriosis to have segmental areas of colon missing its musculature, and wonders about pro.....?

28 year-old woman was found during laparoscopy for endometriosis to have segmental areas of colon missing its musculature, and wonders about pro.....?

Segmental lack muscl: Segmental absence of colonic musculature is congenital and is usually diagnosed in childhood. It can be associated with constipation and also spontaneous perforation which is when it is diagnosed. Would follow up with colon surgeon , regarding the risk for perforation and whether prophylactic removal is warranted .

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What is skeletal dysplasia?

What is skeletal dysplasia?

Abnormal bones: Skeletal dysplasias represent abnormal structure and development of bones. Some are genetic in their development. Dysplasia is classified according to part of bone affected, epiphysis, metaphysis, or diaphysis Bone deformities can develop and often dwarfism is result of bone dysplasia.

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Whats ectodermal dysplasia?

Whats ectodermal dysplasia?

Many types...: Ectodermal dysplasia is a group of conditions in which there is abnormal development of the skin, hair, nails, teeth, or sweat glands. See: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0002440/.

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What is cleidocranial dysplasia?

Bone disease..: Cleidocranial dysplasia is a condition that primarily affects the development of the bones and teeth. It can be inherited from one affected parent, or be a new mutation in an affected individual. It is important for a patient with this disease to see a geneticist. They can help coordinate care with other specialists (bone doctors, dentists) for this disease.

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No evidence of malignancy or dysplasia?

No evidence of malignancy or dysplasia?

Sounds good: But that report has to be taken in context with the circumstances (kind of cancer, type of biopsy, any abnormalities in scans, etc.). Whosoever ordered the test should go over it with you. Hope is real.

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What is cervical dysplasia?

Abnormal cells: This is complicated so stay with me. Hpv is a virus that can infect cells on the cervix. When hpv gets into the cell it can cause the cell to make abnormal proteins. This makes the cell look different under the microscope. If the infection progresses, the cells can become cancerous. This is rare but dysplasia should be addressed. It can go away on its own in some cases. Others need treatment.

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Is level 3 dysplasia cancer?

Is level 3 dysplasia cancer?

No but need followup: Type iii dysplasia ( pap smear ) itself is not cancer means had severe abnormal cells need careful further evaluation , for cancer cells with out invasion ( in situ cancer ) . Must be followed with close observation for any change.

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Can dysplasia lead to cancer?

Can dysplasia lead to cancer?

Yes: Progression from normal cell to cancer is like going from white to black over a grey spectrum that keeps getting darker. Normal cell can become dysplastic-- become severe dysplastic -- become low grade cancer-- become high grade.

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Whats cervical dysplasia mean?

Whats cervical dysplasia mean?

Precancerous cells: Dysplasia of the cervix are cells which are showing cellular changes consistent with pre-cancerous lesions. They are graded as low-grade (atypia or cin-1) or high-grade (cin 2, 3, or carcinoma in situ). Low grade cells can be followed while high grade lesions need to be identified (colposcopy) & removed (leep or cone biopsy).

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What causes Cervical dysplasia?

What causes Cervical dysplasia?

Usually HPV virus: Dysplasia is one of the early steps in mucosal transformation. The phenotypic structure of the mucosal cells begins to transform toward malignant phenotype and can be picked up on Pap. With newer monoclonals defining the immunogenic protein characterizing cervical Ca changes, normal mucosal cells can be shown to expression tumor protein even though the cells look normal, the ImmunoPap.

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What causes dysplasia of cervix?

What causes dysplasia of cervix?

Human Papillomavirus: The most common cause of dysplasia of the uterine cervix is human papillomavirus (hpv). There are several hundred types, but 6, 11, 16, 18, 32, and 33 are the most common. It is a pre-cursor to the development of cancer. However, with cervical cytology (pap smears), people with low grade dysplasia (lgsil) rarely progress, while patients with hgsil will have excision (cone biopsy).

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What is this cervical dysplasia?

Precancerous cells: These are abnormal cells in the cervix that have a potential to turn into cancer but are not yet a cancer.

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Symptoms of epiphyseal dysplasia?

Mild pain: Multiple epiphyseal dysplasia is an inherited disorder, that affects the joints of the long bones in the arms and legs. There are 2 types based on inheritance (either recessive or dominant) symptoms are usually mild, and include joint pain, early arthritis, a waddling gait. Some a have other deformities like scoliosis, malformations of the hands and or feet.

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What's bronchopulmonary dysplasia?

What's bronchopulmonary dysplasia?

Lung scarring: Bronchopulmonary dysplasia is a condition of airway & lung scarring that occurs in premi's & micro premi's during their prolonged need for ventilation or oxygen in those critical weeks. Xrays are seen to gradually change to show the characteristic patterns that correlate with pathology seen under the microscope when a kid doesn't survive.

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Can you survive cortical dysplasia?

Yes: Cortical dysplasia refers to a congenital (present at birth) abnormality in the brain’s development. As the brain naturally develops in utero, neurons migrate outward to the cerebral cortex. Should these neurons fail to spread out and position correctly, the signals will misfire – triggering a seizure. Anti-seizure meds can be used to help patients. How this affects a patient is quite variable.

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What is spondyloepiphyseal dysplasia?

SED is a term…: …describing a group of disorders involving abnormal growth (dysplasia) of the spine (spondylo) & of the growing ends of bones (epiphyseal). It results in disproportionately short trunk & many other abnormalities. The following website covers the topic very thoroughly: http://emedicine.Medscape.Com/article/1260836-overview.

Dr. William Singer
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Dysplasia (Definition)

Abnormal cells which may be pre-malignant, but can also result ...Read more