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Doctor insights on: Uterine Cancer And Low Progesterone

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Does low progesterone cause endometrial cancer?

Does low progesterone cause endometrial cancer?

Estrogen-progesteron: It's the relationship between estrogen levels and Progesterone levels that are important. Too much estrogen not balanced properly by Progesterone can increase risk of endometrial cancer. This can be either too much estrogen or not enough progesterone. ...Read more

Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Will estrogen dominance always cause uterine cancer?

Will estrogen dominance always cause uterine cancer?

Estrogen/Uterine CA: Absolutely not. "high" estrogen levels are only one factor in the risk profile for uterine cancer, which also includes obesity, family history, and oral contraceptive history. Even if you possess one or more risk factors, that does not mean that a tumor is certain. Close monitoring and counselling by your gyn is the best course of action. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

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Do high estrogen levels cause breast cancer in men?

Do high estrogen levels cause breast cancer in men?

IT'S A RISK FACTOR: Prolonged exposure to estrogen is a risk factor for breast cancer in men. Obesity, liver cirrhosis and high alcohol intake can lead to a high estrogen state. ...Read more

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Can estrogen dominance always cause uterine cancer?

Can estrogen dominance always cause uterine cancer?

No, a risk factor: Unopposed estrogen is a risk factor for uterine cancer but it does not always cause it. Unopposed estrogen means it is given without any Progesterone another female hormone. Somewhere between 4-8 out of every 1000 women receiving unopposed estrogen per year will get uterine cancer. Being obese probably makes the risk closer to 8/1000, whereas in thin women the risk is about 4/1000. ...Read more

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Does having breast, endometrial, and ovarian cancer in family history increase one's risk of endometriosis?

Does having breast, endometrial, and ovarian cancer in family history increase one's risk of endometriosis?

Endo: Having family history of ovarian, colon and uterine cancer specially if these are first degree relatives will put you at risk for cancer not for endometriosis. I would recommend that you talk to your doctor and ask about a brca genetic testing to see if you are a carrier of the gene associated with these types of cancer. ...Read more

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Does long term use of estrogen and progesterone lower risk for uterine cancer?

Does long term use of estrogen and progesterone lower risk for uterine cancer?

When combined: It will lower risk if combined in an hormone replacement therapy(HRT) for applicable patients. Estrogen used alone for (HRT) in women who still have a uterus present can increase their risk of uterine cancer.(endometrial) when progesterone is not used. ...Read more

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Can breast cancer cause high fai and low shbg?

Can breast cancer cause high fai and low shbg?

Guessing : "free androgen index" and "sex-hormone binding globulin"? That is news to me. There's a few old correlations with obesity but nothing i could find more recently. I'd reiterate my colleague's request to keep the abbreviations / acronyms to a minimum -- there's way too both in real life and in medicine. I'm wondering why you ask, but i hope this was helpful. ...Read more

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Progesterone and estrogen used for premature ovarian failure?

Progesterone and estrogen used for premature ovarian failure?

Yes: For woman with premature ovarian failure (pof), we recommend hormone replacement therapy, which includes both estrogen and progesterone. The addition of Progesterone is to regulate menstrual period and prevent uterine cancer. For woman desires for pregnancy, we may be able to reduce her fsh level and induce ovulation in some patients. ...Read more

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Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

PCOS: PCOS can increase androgens in patients regardless of their weight. The effects on Estrogen are less clear as these levels fluctuate and typically would not be tested in PCOS. The LH and FSH levels are checked but not Estrogen. The effects of Phytoestrogens such as soy on the risk of breast cancer are debatable. There is not specific recommendation for PCOS patients to avoid them ...Read more

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Is estrogel and progesterone dangerous if your mother died of uterine cancer ?

Probably not: Probably not but best to have a detailed conversation about your family history and other risk factors with your gynecologist. ...Read more

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I have PCOS no periods. High risk of womb cancer, how high? How to be tested? Also high levels of oestrogen and testosterone hormones.

I have PCOS no periods. High risk of womb cancer, how high? How to be tested? Also high levels of oestrogen and testosterone hormones.

Your gynecologist is: The answer can be best obtained from your gynecologist. If you do not have one, you should find one who can help you manage your PCOS. Cancer is not a significant risk for you. I do not think Cancer of the womb is associated with PCOS. ...Read more

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Do post-menopausal women have low levels of estrogen?

Yes: Hi. Yes, loss of estrogen is one of the hallmarks of menopause, and why estrogen/progestin replacement (if uterus in place) or estrogen replacement (if hysterectomized) is beneficial for postmenopausal symptoms. ...Read more

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Low hCG and high progesterone levels.What does this mean in pregnancy?

Low hCG and high progesterone levels.What does this mean in pregnancy?

Usually means you ar: Are early, your obgyn should have explained this to you, in a normal pregnancy the bhcg should double in 3 days, so the bhcg can be repeated. ...Read more

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Should I lower BMI from 20 to 19 to lower estrogen? Had uterine cancer and hysterectomy. Kept ovaries. Afraid of breast/ovarian cancer.

Should I lower BMI from 20 to 19 to lower estrogen?  Had uterine cancer and hysterectomy.  Kept ovaries.  Afraid of breast/ovarian cancer.

No: Your BMI is normal. What stage/grade was your uterine cancer? Is there a family history of breast/ovarian cancer? Your surgeon may be able to provide you with information regarding these risks, may be able to order cancer genetics screening tests if indicated, or may be able to refer you to a cancer genetics counselor should you choose to do so. Best Wishes ...Read more

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40yr old, uterine polyp endo lining thick, estrogen high. No menopause yet. Will amberen work for me to balance hormones?

40yr old, uterine polyp endo lining thick, estrogen high. No menopause yet. Will amberen work for me to balance hormones?

No: I've checked the ingredient list for amberen and do not see anything listed that would be either helpful or harmful in this situation. With a thick lining, high estrogen and a polyp, a cancer or precancer must be ruled-out and treatment with natural Progesterone the best option in many situations. ...Read more

Dr. John Geisler
228 doctors shared insights

Uterine Cancer (Definition)

Also known as cancer of the uterus, this is when cancer grows in the female organ in which the implantation of an embryo and carrying of a fetus take place. Cancer usually develops in the cells that form the uterine--a portion of which are shed ...Read more


Dr. Seth Derman
1,176 doctors shared insights

Progesterone (Definition)

Progesterone has been found to be helpful in preventing preterm birth in a patient who has a history of delivering babies too early. It can be given as vaginal suppositories. It is most often given as weekly ...Read more