Doctor insights on:
Uterine Cancer And Low Progesterone
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Estrogen/Uterine CA: Absolutely not. "high" estrogen levels are only one factor in the risk profile for uterine cancer, which also includes obesity, family history, and oral contraceptive history. Even if you possess one or more risk factors, that does not mean that a tumor is certain. Close monitoring and counselling by your gyn is the best course of action. ...Read moreSee 1 more doctor answer
Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?
Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more
No, a risk factor: Unopposed estrogen is a risk factor for uterine cancer but it does not always cause it. Unopposed estrogen means it is given without any Progesterone another female hormone. Somewhere between 4-8 out of every 1000 women receiving unopposed estrogen per year will get uterine cancer. Being obese probably makes the risk closer to 8/1000, whereas in thin women the risk is about 4/1000. ...Read more
Does having breast, endometrial, and ovarian cancer in family history increase one's risk of endometriosis?
Endo: Having family history of ovarian, colon and uterine cancer specially if these are first degree relatives will put you at risk for cancer not for endometriosis. I would recommend that you talk to your doctor and ask about a brca genetic testing to see if you are a carrier of the gene associated with these types of cancer. ...Read moreSee 2 more doctor answers
Guessing : "free androgen index" and "sex-hormone binding globulin"? That is news to me. There's a few old correlations with obesity but nothing i could find more recently. I'd reiterate my colleague's request to keep the abbreviations / acronyms to a minimum -- there's way too both in real life and in medicine. I'm wondering why you ask, but i hope this was helpful. ...Read moreSee 1 more doctor answer
Are uterine cancer, endometrial / ovarian cancer, and uterine fibroids/other abnormalities detected through pap smear other than cervical cancer?
No.: Pap smears sample cervical cells only.Get a more detailed answer ›
Yes: For woman with premature ovarian failure (pof), we recommend hormone replacement therapy, which includes both estrogen and progesterone. The addition of Progesterone is to regulate menstrual period and prevent uterine cancer. For woman desires for pregnancy, we may be able to reduce her fsh level and induce ovulation in some patients. ...Read moreSee 1 more doctor answer
Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?
PCOS: PCOS can increase androgens in patients regardless of their weight. The effects on Estrogen are less clear as these levels fluctuate and typically would not be tested in PCOS. The LH and FSH levels are checked but not Estrogen. The effects of Phytoestrogens such as soy on the risk of breast cancer are debatable. There is not specific recommendation for PCOS patients to avoid them ...Read more
I have PCOS no periods. High risk of womb cancer, how high? How to be tested? Also high levels of oestrogen and testosterone hormones.
Should I lower BMI from 20 to 19 to lower estrogen? Had uterine cancer and hysterectomy. Kept ovaries. Afraid of breast/ovarian cancer.
No: Your BMI is normal. What stage/grade was your uterine cancer? Is there a family history of breast/ovarian cancer? Your surgeon may be able to provide you with information regarding these risks, may be able to order cancer genetics screening tests if indicated, or may be able to refer you to a cancer genetics counselor should you choose to do so. Best Wishes ...Read more
40yr old, uterine polyp endo lining thick, estrogen high. No menopause yet. Will amberen work for me to balance hormones?
No: I've checked the ingredient list for amberen and do not see anything listed that would be either helpful or harmful in this situation. With a thick lining, high estrogen and a polyp, a cancer or precancer must be ruled-out and treatment with natural Progesterone the best option in many situations. ...Read more
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