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Doctor insights on: Uterine Biopsy Results

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Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component specimen: uterine evacuation?

Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component

specimen: uterine evacuation?

Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more

Dr. Jeffrey Wint
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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Endometrial biopsy 3/3/15 results - tubal metaplasia and scant sample, so d&c hysteropscopy 04/14/15 results show no tubal metaplasia can it reverse?

Endometrial biopsy 3/3/15 results - tubal metaplasia and scant sample, so d&c hysteropscopy 04/14/15 results show no tubal metaplasia can it reverse?

Insignificant find: Tubal metaplasia is an insignificant finding in endometrial tissue. Often it is not even mentioned because it is common. It has no association with hyperplasia or cancer at all. It is an incidental finding that is usually present only focally. Your MD undoubtedly repeated the biopsy because the initial biopsy was scant and s/he wanted a better sample, NOT to see if there is more metaplasia. ...Read more

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How accurate is an office hysteroscopy endometrial biopsy &polypectomy in showing cancer or hyperplasia?

How accurate is an office hysteroscopy endometrial biopsy &polypectomy  in showing cancer or hyperplasia?

Not entirely - : To make these diagnoses - of cancer and hyperplasia - a pathologist really must examine slides of biopsies or smears. These diagnoses cannot be made with any certainty without microscopic examination. ...Read more

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Normal pap but ultrasound shoes uterine thickening with polyp?

Normal pap but ultrasound shoes uterine thickening with polyp?

Pap smears: Pap smears allow pathologists to evaluate cells from the cervix (the outside or ectocervix and inside or endocervix). Most of the time we do not find cells from the endometrial cavity in the test slide because the pap smear collection brush should not go into the endometrium. Additional biopsies are required to evaluate endometrial pathology. ...Read more

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Could a trans-vaginal ultrasound detect endometrial hyperplasia?

Could a trans-vaginal ultrasound detect endometrial hyperplasia?

Hard to be certain: Ultrasound is never 100%, but several findings are suspicious for endometrial hyperplasia or even cancer. For instance, if your lining is excessively thick for your age or if there is a suspicious mass seen within the uterine cavity on the sonogram, hyperplasia or cancer may be present. However, other findings can cause similar images on sonogram. Also, diagnosis can only be made with a biopsy. ...Read more

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Atypical glandular cells - favor neoplastic was my pap smear test result. Negative colposcopy- & endocervical curretings result. Please explain.

Maybe benign and overcall: It is possible that the cells are reactive and they were over called as worrisome for cancer but in fact are completely normal this would explain the findings. You should have me look at the pap smear i will give you the right answer. ...Read more

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If pap smear test suggestive of lsil does it reqd biopsy before fibroid removal?

If pap smear test suggestive of lsil does it reqd biopsy before fibroid removal?

Colposcopy: If you had an abnormal pap smear then the next step is an examination under a microscope called a colposcopy. This will evaluate the extent of the problem and will guide the next steps in management. Abnormal pap smears may indicate HPV changes or precancerous cells of the cervix. This is not related to uterine fibroids. ...Read more

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Leep shows hsil cin3 w/ endocervical gland involvement. Exocervical margins positive. Endocervical margins clear. Pap in 3 months or cone biopsy now?

Leep shows hsil cin3 w/ endocervical gland involvement. Exocervical margins positive.  Endocervical margins clear.  Pap in 3 months or cone biopsy now?

At least PAP, may: Require bone biopsy later. From the information you provided, you have residual abnormal cells in the cervix and at a minimum you need to monitor the process by pap. Three months is not likely to cause irreversible changes for the worse and you can wait to see the pap results to decide, in consultation with your doctor, if cone biopsy is needed. ...Read more

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Can a pap smear diagnose uterine cancer? Can uterine cancer show up on a pap smear test? .

Can a pap smear diagnose uterine cancer? Can uterine cancer show up on a pap smear test?

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Yes: Pap smear may pick up endometrial cancer, but it will miss more than it will pick up. Pap is far more useful for detecting cancer of the uterine cervix. ...Read more

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What does it mean? Inactive endometrium with focal tubal metaplasia? Benign endometrial polyp.

What does it mean?
Inactive endometrium with focal tubal metaplasia?
Benign endometrial polyp.

It is not serious: Your doctor should be able to explain it better. But this report indicates that you have some benign changes in the lining of your uterus...No cancer found. ...Read more

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Are abnormal cells removed with a colposcopy biopsy?

Are abnormal cells removed with a colposcopy biopsy?

Preventing Cancer: It's VERY important to get a colposcopy if your pap is abnormal. A colposcopy is a speculum exam where special stains and magnifying lenses are used to look for pre-cancers on your cervix. If there are abnormalities, your GYN will take a biopsy, which is uncomfortable, but lasts ...Read more

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Pap smear and it came back with HSIL then biopsy which came back cervix uteri/uterine cervix squamous metaplasia/epidermioid met/epidermailzation?

Pap smear and it came back with HSIL then biopsy which came back cervix uteri/uterine cervix squamous metaplasia/epidermioid met/epidermailzation?

Further evaluation: consider further evaluation, possibly a LEEP procedure. At a minimum, repeat pap in 6 -12 months with HPV testing. ...Read more

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Do endometrial injury by means of endometrium biopsy improves implantation rates?

No!: This is sort of an older idea: interesting concept but very few experts believe this nowadays. Endometrial biopsy to "improve implantation rates" should absolutely not be done routinely. ...Read more

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Endometrial cells on pap means cancer?

Endometrial cells on pap means cancer?

Generally no.: Endometrial cells can be 'normal' in a pap test depending upon the age of the patient and the time of the menstrual cycle in which the test was performed. If a pap is collected in a premenopausal woman within 10 days of the onset of bleeding / menses, then the endometrial cells are most likely part of uterine shedding. In postmenopausal women, a finding of endometrial cells needs explanation. ...Read more

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Biopsy results says Mid Secretory Endometrium. endometirial biopsy, are fragments of tan spongy soft tissue. 1.0x1,0x0.2. What does it mean?

Biopsy results says Mid Secretory Endometrium. endometirial biopsy, are fragments of tan spongy soft tissue. 1.0x1,0x0.2. What does it mean?

Endometrial biopsy: Your result indicate that at the time of your biopsy you were in the secretory or second phase of your cycle just before menstruation. Good things to know: no evidence of hyperplasia (pretumor growth) or malignancy. Sounds like a normal biopsy. ...Read more

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Petrified last 4 yrs had 3 hysteroscopies w/ DNC biopsy ALL BENIGN 1 pap with endometrial cells 4 uterine polyps how likely missing cancer diagnosis?

Petrified last 4 yrs had 3 hysteroscopies w/ DNC  biopsy ALL BENIGN 1 pap with endometrial cells  4 uterine polyps how likely missing cancer diagnosis?

All biopsies negativ: That's great news to be celebrated! Do you have a family history of breast or uterine cancer? Are you BRCA positive? Have you had mammograms or colonoscopies done? Why are you petrified? Speak to your doc about your fears and address them. You seem to be partly doing that already. ...Read more

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Endometrial sqamous metaplastic cells endo biopsy has been done?

Please clarify: Pap smears and biopsies often show both squamous metaplastic endocervical cels and endometrial cells. Beyond a heads-up that hpv may be present, squamous metaplasia isn't a great concern. If you can rephrase what you are asking, someone here will be glad to help. ...Read more

Uterus (Definition)

The uterus is a muscular organ in a woman's pelvis where the the fertilized egg attaches ...Read more