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Doctor insights on: Use Of Anticoagulants And Infliximab

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Dr. Boris Aronzon
532 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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Whats are the side effects of using slazopyrine with anabolic steroids for RA patients?

Whats are the side effects of using slazopyrine with anabolic steroids for RA patients?

Sulfasalzine ok, but: I use sulfasalzine 5500mg-dr as one of my first line drugs. Anabolic steroids if administered orally are quite dangerous. If low testosterone exists in either sex, it should be repleated. Of note is the fact that in this female dominant disease, many men are hypogonadal. There are no specific protocols for using anabolics (which one) with ra. However, there are protocals for treating low-t. ...Read more

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What are the potential side effects of using the prohormone halodrol while taking remicade (infliximab) for Crohn's (been in remission for over a year)?

What are the potential side effects of using the prohormone halodrol while taking remicade (infliximab) for Crohn's (been in remission for over a year)?

Unknown: As is true for most of the supplements sold over the counter, they are not regulated by the fda. They may or may not contain what is written on the label. There are no studies that demonstrate that they do what they claim to do, and there certainly are no studies to see if they can interact with medications taken for other problems. There are better ways to waste your money. ...Read more

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What are the risks of long-term use of trimethoprim-sulfamethaoxazole antibiotic for treatment of inflammatory rosacea? How to mitigate risks?

What are the risks of long-term use of trimethoprim-sulfamethaoxazole antibiotic for treatment of inflammatory rosacea? How to mitigate risks?

Drug allergy: The sulfonamides ("sulfa drugs") are among the most common causes of allergic skin rash. Most people never develop rash, but it's possible this could happen in the future. There is nothing that can prevent allergic reactions. No other important side effects are likely; this is a veyr safe drug. Discuss w/ your doctor if you remain concerned. ...Read more

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What are the effects of using too much Coumadin (warfarin) and aspirin ?

What are the effects of using too much Coumadin (warfarin) and aspirin ?

Risk of bleeding: Aspirin can cause bleeding in the stomach because of stomach irritation. It can also cause bleeding because of its effect on platelet function. {platelets are necessary to make bleeding stop.) Coumadin (warfarin) can cause bleeding because of its effect on the body's ability to stop bleeding by a different means from what platelets do. So too much of both can increase you risk of bleeding a lot. ...Read more

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What do you think of the combination of celebrex (celecoxib) and sulfasalazine to treat RA beside taking other medications such as methotrexate and Enbrel ? Instead of Norco or motrin or tramadol

What do you think of the combination of celebrex (celecoxib) and sulfasalazine to treat RA beside taking other medications such as methotrexate and Enbrel ? Instead of Norco or motrin or tramadol

Depends on severity: It depends on the severity and activity of your RA. Enbrel and Methotrexate are great drugs if you have active. If it is not active Celebrex (celecoxib) and sulfasalazine are alternatives. We discourage people to use narcotic painkillers for non cancer pain for the long term since it is very addictive and people become tolerant for the doses and expect increasing doses ...Read more

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What are the effects of extended use of IV merapenem?

What are the effects of  extended use of IV merapenem?

Merrem: Merrem is an antibacterial antibiotic belonging to the family of carbopenems. It is generally used for skin, intraabdominal and meningitis in children. Usual side effects to look for hypersensitivity reactions, interaction with valproic acid, seizure potential. Clostridium difficile enteritis, caution in hemodialysis patients. ...Read more

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For uedvt, is warfarin the only option? I've heard of some new ones...Pradaxa? Also, is heparin and lmwh as effective as these pill forms?

For uedvt, is warfarin the only option? I've heard of some new ones...Pradaxa? Also, is heparin and lmwh as effective as these pill forms?

UEDVT: There are new drugs, pradaxa, rivaroxaban and apixaban which are approved for ledvt, they could be tried for ue. I haven't seen any ue studies with them. Heparin forms are effective. ...Read more

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If I take Rivaroxaban with alcohol will the anticoagulant effect of both of them be dangerous?thanks

If I take Rivaroxaban with alcohol will the anticoagulant effect of both of them be dangerous?thanks

Probably not: Alcohol does not have any significant effect ob blood coagulation. But at your age it is best to avoid/minimize use of alcohol as it has so many other bad effects like Falls, and poor quality of sleep ...Read more

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What kind of rub to use for arthritis while taking warfarin?

What kind of rub to use for arthritis while taking warfarin?

IcyHot, Zostrix (capsaicin): Glad you asked. Warfarin (brand coumadin) has many interactions with other drugs that make it less effective or dangerously high leading to bleeding. Most topical rubs such as bengay, icyhot or capsasin should be ok. I would avoid topical aspirin. ...Read more

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Why we use antimalarial drugs in treatment of systemic manifestations of sle?

Why we use antimalarial drugs in treatment of systemic manifestations of sle?

See details: Hydroxyxhloroquine (plaquenil) is used because it is not only proven to be effective in treating the common manifestations of lupus but it helps to prevent more serious problems from occurring in the future. ...Read more

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Why are anticoagulants and antiplatelet drugs commonly used in atherosclerosis treatment?

Why are anticoagulants and antiplatelet drugs commonly used in atherosclerosis treatment?

Plaque and clot: atherosclerosis has been renamed atherothrombosis: plaque and clot formation. Statins lower cholesterol to slow plaque formation. Antiplatelet agents are used to block platelets to prevent clot formation and antithrombotics are used during an acute heart attack. It boils down to inflammation from poor diet, smoking causing vessel injury and plaque builds as a healing reaction. ...Read more

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What are the alternatives to Aspirin in dual antiplatelet therapy?

There are several: clopidogrel, dipyridamole, tirofiban, ticagetor, cilostazol, prasugrel, eptifibatide, ticlopidine all are classified as anti-platlet drugs and are an alternative to aspirin ...Read more

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In treating Rheumatoid Arthritis, what are the pros/cons of managing it long-term with Prednisone vs. DMARDs? Do all DMARDs increase cancer rates?

See details: Prednisone has major side effects far worse than DMARDs and it does not prevent joint damage. There is a very small increase risk of lymphoma with some DMARDs. As a rheumatologist I try to never use prednisone long term. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Dr. Jeremy Adler
128 doctors shared insights

Infliximab (Definition)

Infliximab is an ...Read more