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Doctor insights on: Urine Osmolality

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Why does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Why  does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Leakage of protein,,: This is likely due to the fact that there is failure of the basement membrane to contain large molecules like proteins, etc.. Also in some cases, oliguria can occur, which means anything in the urine can get concentrated even more than it should be. Proteinuria can be almost 3 g/day. ...Read more

Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more


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Is it possible to get a false negative on a zinc toxicity test? I had zinc, copper and lead testing done. My zinc results in blood and urine were at the high end of normal. My lead was negative but my copper results came back as low. I have all of the

Any : Any test has a risk of being a false negative or even false positve for that matter. Heavy metal toxicity/poisoning is a very difficult issue, and has been a challenge for a lot of doctors. I recommend you consult a medical toxicologist. These doctors specialize in poison and metal toxicity. If you have already done so, i suggest a second opinion by another doctor in the field. Good luck. ...Read more

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Dealing with Blood in Urine (Checklist)

Rule out infection as a cause with a urinalysis or culture
Once
Ask your doctor to review your medications, to identify cause
Once
Rule out kidney stones with your doctor
Once
If male, schedule a prostate exam
Once
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Why is urine osmolality low in post renal failure?

Why is urine osmolality low in post renal failure?

Need time to heal: Acute kidney failure involves damage to the cells lining the kidney tubules (nephrons) which take days to regrow and repair. These cells then reestablish the high osmotic gradient in the kidney pyramids that enable concentration of urine. Until the cells regrow and the osmotic gradient is reformed, urine osmolality will be low. ...Read more

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Why is urine osmolality low in post renal failure?

Need time to heal: Acute kidney failure involves damage to the cells lining the kidney tubules (nephrons) which take days to regrow and repair. These cells then reestablish the high osmotic gradient in the kidney pyramids that enable concentration of urine. Until the cells regrow and the osmotic gradient is reformed, urine osmolality will be low. ...Read more

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Why does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Leakage of protein,,: This is likely due to the fact that there is failure of the basement membrane to contain large molecules like proteins, etc.. Also in some cases, oliguria can occur, which means anything in the urine can get concentrated even more than it should be. Proteinuria can be almost 3 g/day. ...Read more

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I am 20 years old with medical issues, I was ordered for blood tests and urine test. My ketones were 15, Squam Epithel, UA was 5-10, OSMOLALITY was at 272L. They were all flagged abnormal should I be worried?

I am 20 years old with medical issues, I was ordered for blood tests and urine test. My ketones were 15, Squam Epithel, UA was 5-10, OSMOLALITY was at 272L. They were all flagged abnormal should I be worried?

Need follow up: Any abnormal results need a follow up with the physician who ordered them. Interpretation of the abnormals must be done within the context of clinical symptoms and results of other tests ...Read more

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These are some blood test results and maybe urine, RBC 3.93 M/mcL ,Hgb POC 11.9 g/DL, Sodium Lvl 132 mol/L,Osmolality 256 mOsm/kg. They r low. Ideas?

These are some blood test results and maybe urine, RBC 3.93 M/mcL ,Hgb POC 11.9 g/DL, Sodium Lvl 132 mol/L,Osmolality 256 mOsm/kg. They r low. Ideas?

Out of Context: One cannot interpret labs without the whole panel there. A doctor providing your an interpretation needs medical history, the reason the tests were ordered and the whole test. You are asking the impossible with these lab values out of context. ...Read more

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Is it possible for aldosterone to make urine hypoosmiotic and concentrated?

Is it possible for aldosterone to make urine hypoosmiotic and concentrated?

Physiology: Hi. Aldosterone is primarily there to regulate renal handling of sodium, potassium, and acid. Urine concentration/osmolality is more a function of anti-diuretic hormone (ADH) regulating tubular luminal water channels and the ambient solute gradient in the loop of Henle. Water follows sodium in general, but the kidneys place quite a degree of regulation on this, so aldo has trivial effect on conc. ...Read more

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In hospital w/supposed di. Currently on water depravation test. 4hrs in volume has lessened greatly and urine is concentrating. Dr suggests polydipsia?

In hospital w/supposed di. Currently on water depravation test. 4hrs in volume has lessened greatly and urine is concentrating. Dr suggests polydipsia?

H2O Depriv Test & DI: Yes. The ability to concentrate to that extent would be unheard of w/ central or nephrogenic di. Are they/or have they done any other tests, besides the obligatory urine osmolality before the test? Did they ever do an ADH serum level? They might not need to, depending on the outcome of your current tests. Let me know how it goes. Remember, if you haven't already, use my "secret code". ...Read more

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