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Doctor insights on: Uremia Frost

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What is gastrointestinal uremic poisoning?

What is gastrointestinal uremic poisoning?

Perhaps: you are referring to the deterioration in renal function that happens when there is a massive gastrointestinal bleeding where there is low volume and absorption of a high protein material ...Read more

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What does uremic poisoning mean?

What does uremic poisoning mean?

Uremia: Uremia refers to buildup of products of metabolism with regard to the Urea Cycle, a process that allows us to excrete nitrogenous waste from our kidneys. Perturbations in renal function leads to buildup of these products associated with acid base and electrolyte issues that are also related to kidney function. Uremia is treated with dialysis to remove the toxins, can cause seizures, cardiac arrest ...Read more

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Why does carbon monoxide poisoning produce rosy cheeks?

Why does carbon monoxide poisoning produce rosy cheeks?

"Fake" oygen: Hemoglobin, the oxygen-carrying molecule in red blood cells, turns bright red when it is attached to oxygen molecules. Carbon monoxide causes its toxic affects by binding to hemoglobin at the same sites and not letting go, preventing oxygen transport. While bound, carbon monoxide also causes the same color change, causing a characteristic "cherry red" appearance despite oxygen starvation. ...Read more

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What is metabolic acidosis in chronic renal failure from?

Dr. Jay Park Dr. Park
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What is metabolic acidosis in chronic renal failure from?

Unable to remove: Metabolic acidosis is a constituent of renal failure, arising mainly from the inability of kidney to remove excess acids in blood. ...Read more

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How common is lactic acidosis with sepsis?

How common is lactic acidosis with sepsis?

With septic shock: It is a marker for end organ damage due to inadequate oxygen reception or utilization. When sepsis progresses to shock we will follow lactate (its pka is 4, so its never really acid in the blood) as a marker of our success in getting blood and oxygen to the peripheral tissues. So... In sepsis itself (without shock) it is rare, but in septic shock lactate is almost always elevated. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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How does uremia cause fibrinous pericarditis?

How does uremia cause fibrinous pericarditis?

Unknown : No one knows what specific toxin(s) accumulate that can lead to uremic pericarditis - not everyone who has severe uremia will develop it. ...Read more

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Isolated gross hematuria dysmorphic rbc. Elevated ck. Mild hypertension. Early androgentc alopecia. Had severe flu 1yr ago. In winter raynauds r hand.

Isolated gross hematuria dysmorphic rbc. Elevated ck. Mild hypertension. Early androgentc alopecia. Had severe flu 1yr ago. In winter raynauds r hand.

The interest: Is in the right handed raynaud's. The body is normally controlled asymmetrically. If oxidative function in brain becomes inefficient, the asymmetry increases. So you might find that the left arm blood pressure is different from the right when taken at the same time by 2 operators. Raynaud is complicated but the asymmetry is unusual. A nutritionist doc might help. ...Read more

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Does dying from septic shock & kidney failure hurt?

Does dying from septic shock & kidney failure hurt?

Who knows?: Clinical experience shows all dying persons will, as expected, struggle to cope with reality, certainty, & uncertainty for survival & continuation at the early stage of dying, gradually become less energy & ability to fight on, then lapse into coma, and finally step into eternity. What is the pace of dying? It heavily depends upon the availability of supportive care & widely vary from days to... ...Read more

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How do chicken pox cause acute glomerolu nephritis?

Dr. Jay Park Dr. Park
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How do chicken pox cause acute glomerolu nephritis?

Not clear: There are a number of viral infections identified as uncommon causes for glomerulonephritis. Hepatitis b and HIV are also well known culprits. ...Read more

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What's the pathophysiology of lactic acidosis in von gierki's disease?

What's the pathophysiology of lactic acidosis in von gierki's disease?

See below: La arises from impairment of gluconeogenesis. Lactic acid is generated both in the liver and muscle and is oxidized to pyruvic acid and then converted via the gluconeogenenic pathway to g6p. Accumulation of g6p inhibits conversion of lactate to pyruvate. The Lactic Acid level rises during fasting as glucose falls. In people with gsd i, it may not fall entirely to normal even when gluc levels r nml. ...Read more

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How typical or rare is carbon monoxide poisoning?

How typical or rare is carbon monoxide poisoning?

Carbon monoxide: Overall it is rare, however each year: 400 Americans (out of 310 million) die from unintentional carbon monoxide poisoning, more than 20,000 visit the emergency room and more than 4,000 are hospitalized due to this issue. Fatality is highest among Americans 65 and older. ...Read more

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What causes death with carbon monoxide poisoning?

What causes death with carbon monoxide poisoning?

Poor oxygen supply: Carbon dioxide causes its toxic effects by reducing the ability of the blood to carry oxygen. This lack of oxygen, if severe and prolonged, can lead to stroke, heart attack, and eventual death. ...Read more

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Are uremia and uremic syndrome the same thing?

Are uremia and uremic syndrome the same thing?

Uremia: uremia is high blood urea. Uremic syndrome is the constellation of symptoms that come from having too much urea in the blood. The higher the urea the more manifestations of the syndrome you will have. Uremic frost is found only when it is very high. ...Read more

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Is serum Osmolality typically elevated in metabolic acidosis/alkalosis and ethylene glycol poisoning?

Is serum Osmolality typically elevated in metabolic acidosis/alkalosis and ethylene glycol poisoning?

Yes: Particularly with ethylene glycol poisoning. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more