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Doctor insights on: Undifferentiated Connective Tissue Disease

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What is undifferentiated connective tissue disease?

What is undifferentiated connective tissue disease?

Type not clear: Undifferentiated connective-tissue disease (uctd) is a diagnosis applied to signs and symptoms that are consistent with a connective-tissue disease (ctd) but that do not fulfill the classification or diagnostic criteria for any one of the defined ctds such as (rheumatoid arthritis, lupus, etc..). ...Read more

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Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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What is undifferentiated connective tissue disease in lay man's terms?

What is undifferentiated connective tissue disease in lay man's terms?

Mixture of many: It is a mixture of findings from a variety connective tissue diseases including systemic lupus erythematosus, rheumatoid arthritis, polymyositis and scleroderma. One does not have allof the symptoms at one time but can overlap from one to another with arthritis, rashes, internal involvement of lungs, heart, kidney less often. ...Read more

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I am being treated for undifferentiated connective tissue disease which can be debilitating during flares. Is it likely I will stay in this limbo diagnosis forever?

I am being treated for undifferentiated connective tissue disease which can be debilitating during flares. Is it likely I will stay in this limbo diagnosis forever?

Possible: As you probably now by now, this condition waxes and wanes with no rhyme or reason. Sometimes, however, patients enjoy long periods of remission which is quite possible to be the case here although no body can foretell. ...Read more

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What's the difference between fibromyalgia and an undifferentiated connective tissue disease?

What's the difference between fibromyalgia and an undifferentiated connective tissue disease?

A LOT!: Any connective tissue disease (ctd) is essentially autoimmune, in nature, meaning the body is attacking itself. 'undifferentiated' may mean it's not classified or not classifiable, but still bears the hallmarks of inflammation & autoimmunity. No one can really agree what fibromyalgia is or what it's cause(s) are, but it does not appear to be autoimmune. Treatments for the 2 are very different. ...Read more

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How long does it take for plaquinil to start working for undifferentiated connective tissue disease?

How long does it take for plaquinil to start working for undifferentiated connective tissue disease?

Several months: Plaquenil can take from 6 weeks to 3 months or more and should be used in conjunction with h=the other modalities like PT and the other meds, like Cymbalta, (duloxetine) that you are already doing ...Read more

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Does having undifferentiated connective tissue disease mean I could have severe health problems if I contracted HSV2?

Why do you ask?: Please make every effort not to contract this virus. Even if you are healthy, this can give you recurrent meningitis, seriously damage your babies, and so forth. A catastrophic fatal infection isn't going to result, but you'll want to avoid this virus as best you can. Best wishes. ...Read more

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I have had interstital cystitis for yrs & undifferentiated connective tissue disease--(not tied down to diagnosis yet). Do you think they are related?

It is a possibility: Although there isn't much is known about the cause of interstitial cystitis, it is a result of inflammation (unkown cause) of the bladder and/or urethral area. Mixed (undifferentiated) connective tissue disease is also an inflammatory condition of various tissues, including bladder etc..So, it is possible that the 2 r related, but relationship is not well-defined, yet. Consult your doc. Good luck. ...Read more

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Anaplastic (Definition)

This largely relates to cancer cells and is a description of how variant the structure and division pattern is from normal cells. An anaplastic cells has weird internal componens, sometimes extra nuclei, and a bizarre pattern of division. They are usually more rapidly dividing and are a serious type of abnormality ...Read more


Connective Tissue (Definition)

There are many types of connective tissue, but in general it is a mass of fibers and thick "goopy" fluids secreted by specialized cells. The body often uses connective tissue to help ...Read more