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Doctor insights on: Undiagnosed Lupus Leukopenia

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

Dr. Eric Weisman
1 doctor shared a insight

Leukopenia (Definition)

This term is generic for any low total ...Read more


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Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd lupus.Possible w/normal labs?

Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd  lupus.Possible w/normal labs?

Lupus: Seems consistent with SLE . Need Rheumatologist follow up and specific anti double stranded DNA and other labs. SLE affects your kidney and can cause pericarditis. Immediate follow and management is helpful. ...Read more

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Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.

Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.

Yes: The presence of an autoimmune disorder points to dysregulation of the immune system and thus one is far more likely to have other autoimmune diseases . However, it is not directly linked to viral hepatitis or AML. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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Whats death rate related to systemic lupus erythematosis?

Whats death rate related to systemic lupus erythematosis?

Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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How is autoimmune hemolytic anemia diagnosed?

Bloodwork: An examination may reveal an enlarged spleen. Tests include: direct coombs' test hemoglobin in the urine indirect coombs' test red blood cell count and serum hemoglobin reticulocyte count serum bilirubin levels serum haptoglobin. ...Read more

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Dr. Alfred Kim Dr. Kim
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What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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P-Anca positive, negative MPO??? Wegener's vasculitis suspected due to clinical symptoms. 6 yr old with juvenile arthritis.

P-Anca positive, negative MPO??? Wegener's vasculitis suspected due to clinical symptoms. 6 yr old with juvenile arthritis.

Autoimmune: The positive ANCA test supports the diagnosis of an autoimmune disorder but with a negative MPO test (of one the proteins in the neurophils targeted by the disease) the possible diagnoses are many including Wegener's, RA, and others. Further testing including a biopsy may be required. ...Read more

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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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Can plaquenil (hydroxychloroquine) (for autoimmune disease) cause increased infections?

Can plaquenil (hydroxychloroquine) (for autoimmune disease) cause increased infections?

Not commonly: Unlike many meds used to treat autoimmune diseases (immune modulators that suppress the immune system) Plaquenil (hydroxychloroquine) has an antiinflammatory effect on autoimmune dss. So the risk of infections (seen with immune suppression) is uncommon. Major concern with this drug is effect on vision. Regular eye exams are recommended. ...Read more

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Lupus and chronic hives, related?

occasionally: Occasionally people with lupus get hives, but most people with hives do not have lupus. ...Read more

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Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read more

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Disease processes associated with a high positive ANA other than autoimmune disorders?

Disease processes associated with a high positive ANA other than autoimmune disorders?

Positive ANA: Conditions that can result in an elevated ANA include autoimmune disorders, certain drugs, uncommon infections, chronic lung or liver disease, kidney failure, ultraviolet light therapy, malignancy, pregnancy, and false positive/lab error. Hope this helps. ...Read more

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Can jak 2 positive. Polycythemia vera cause chronic low grade fevers?

Can jak 2 positive. Polycythemia vera cause chronic low grade fevers?

No: Pv by itself does'nt cause low grade fevers. However, pv can increase your risk to have blood clots and blood clots can give you low grade fevers also, pv can transform into other condition i.E myelofibrosis as well as mds/ acute leukemia in about 20%-30%). Low grade fevers occur quite commonly in myelofibrosis and acute leukemia. See your md to rule out other condition i.e. Autoimmune , infection. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

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If lupus went into remission & i no longer needed methotrexate, would it likely cause leukopenia or not?

If lupus went into remission & i no longer needed methotrexate, would it likely cause leukopenia or not?

Lupus can cause leukopenia: Lupus can cause leukopenia. Methotrexate can cause leukopenia. So the reason you might have it depends on the rest of the manifestations of your lupus. Other reasons besides Methotrexate lupus can also cause leukopenia. Thus your evaluation would try to clarify all of this. ...Read more

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Is it fairly common or possible 2have mostly negative lab workup with lupus. I have lupus & only abnormal labs is high +ANA and occassional leukopenia?

Is it fairly common or possible 2have mostly negative lab workup with lupus. I have lupus & only abnormal labs is high +ANA and occassional leukopenia?

Diagnostic criteria: Diagnosis of lupus requires meeting multiple criteria. Please consult this site for information on these. http://lupusresearchinstitute.org/lupus-facts/lupus-diagnosis ...Read more

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If lupus went into remission & person no longer needed methotrexate, would methotrexate likely cause leukopenia (in someone with normal higher wbc)?

If lupus went into remission & person no longer needed methotrexate, would methotrexate likely cause leukopenia (in someone with normal higher wbc)?

see details: The question does not make sense. Leukopenia is a side effect of Methotrexate but is commonly seen in lupus patients who never receive this medication. It can persist even when the disease is otherwise quiet. ...Read more

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Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd lupus.Possible w/normal labs?

Lupus: Seems consistent with SLE . Need Rheumatologist follow up and specific anti double stranded DNA and other labs. SLE affects your kidney and can cause pericarditis. Immediate follow and management is helpful. ...Read more

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Could undiagnosed lupus lead to complications with needing multiple abd. Surgies..Body attacking itself?

Could undiagnosed lupus lead to complications with needing multiple abd. Surgies..Body attacking itself?

Maybe : Lupus, which is an autoimmune disorder, usually affects joints and skin but can have affect internal organs as well as blood vessels. Vasculitis, which involves blood vessel inflammation, is one way in which it can affect many orgran systems at once and lead to serious complications. If there is concern of lupus a thorough history, exam and diagnostic workup should be done to confirm. ...Read more

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Why was I diagnosed and then undiagnosed with lupus? Is my doctor incompetent?

Why was I diagnosed and then undiagnosed with lupus? Is my doctor incompetent?

See details: How can anyone possibly answered that question without knowing your entire history and having access to all of your lab results.See a rheumatologist if you have not done so already. If you are concerned, get a second opinion. ...Read more

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Doctors thinking lupus, still undiagnosed. Took Medrol (methylprednisolone) pack, symptoms got better. Finished pills, numbness spreading and new pains. Why? Normal?

See below: Corticosteriods will make all pain go away, but these are not be used for just any pain. They are reserved for certain conditions such as autoimmune diseases because of the extensive side effects that these medications have. ...Read more

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I have undiagnosed lupus. We still take tests but i show many signs. I have recently noticed some new bumps on my forearm that are clustered together. I also have one on my neck and one on my breast.

I have undiagnosed lupus. We still take tests but i show many signs. I have recently noticed some new bumps on my forearm that are clustered together. I also have one on my neck and one on my breast.

Lupus?: Why do you think it is lupus? Have you consulted with a rheumatologist? If so and "many tests were done" and it is still "undiagnosed" then it most likely not lupus and there is something else going on. If you have not seen a rheumatologist, then it is time to do so and to trust the advice they give you. ...Read more

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My dsdna double strand reference was 3.45 and very symptomatic.. S this a positive for lupus how is it scored?

Possibly: this is one of the many blood tests used to diagnose lupus..you should consult your rheumatologist to have them run a full battery of tests ...Read more

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This last 2 weeks feel so run down between p.O.T.S and lupus... Im 27 i want to feel normal. But i don't think ill ever be "normal" again. :/?

See below: Go the lupus foundation of america's website to find a support group for lupus patients near you. I think you would find this beneficial and you would also learn how other patients cope with the disease. ...Read more

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What;s the best pain medicine for lupus patients?

What;s the best pain medicine for lupus patients?

Acetaminophen NSAIDS: For symptom relief of pain you can use Acetaminophen or NSAIDs like Ibuprofen or o Naprooxen or Cox 2 Celebrex Along wih Antimalarials (Hydroxychlroquin) and low dose steroids ...Read more

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Is it ok for s.l.e lupus patients to take suppliments for gym workouts such as, Karbolyn xr3, stance bcaa, gluamatic

Is it ok for s.l.e lupus patients to take suppliments for gym workouts such as, Karbolyn xr3, stance bcaa, gluamatic

Not sure, I don't : think anyone knows for sure if its okay for sure. No study has been done on those supplement with SLE. I would recommend stay simple supplement with multivitamin, Vit D, B complex. At the most, protein shake for post work out. ...Read more

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How to tell if I have t1 diabetes, lupus and m.S at age 17?

How to tell if I have t1 diabetes, lupus and m.S at age 17?

Not likely: Why worry about 3 disorders, as you likely possess one unifying diagnosis to explain your problems. A good place to start is with an endocrinologist to deal with diabetes and the complications secondary to this. Focus on these issues, and later, if things seem peculiar look into co-morbities. Lastly, if you possess diabetes and lupus, doubt you have ms in addition. ...Read more

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Both my mom and aunt have been diagnosed with lupus, should I get checked for it as well? Since I know it’s hereditary

Both my mom and aunt have been diagnosed with lupus, should I get checked for it as well? Since I know it’s hereditary

Rheumatologic issues: The specific diagnosis of lupus wouldn't run in families as much as the tendency towards rheumatologic conditions in general - that tendency runs in families - lupus, rheumatoid arthritis, Sjögren's syndrome, scleroderma. Can find all of these in family lineages. Have a good history/physical exam/blood testing coordinated by Rheumatologist. ...Read more

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Could leukopenia cause reduction in height?

Could leukopenia cause reduction in height?

No: Leukopenia (white blood cells in the blood are fewer than normal) does not cause reduction a child's final height. However, if the leukopenia was severe, and the child had persistent or recurrent infections throughout childhood, he might not grow as tall due to having chronic illnesses. In an adult, leukopenia does not make him shorter. ...Read more

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Can men have lupus?

Yes: Lupus is an auto-immune disorder that can affect various organs including the skin, joints, kidneys, brain, etc. Males and females can get lupus. Check out lupus.Org for more information. ...Read more

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Can i fast in lupus?

See below: Without knowing your full history of lupus, i advise against it but your rheumatologist knows your more than we do. ...Read more