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Doctor insights on: Undiagnosed Lupus Leukopenia

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

Dr. Andrew Berry
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Leukopenia (Definition)

This term is generic for any low total ...Read more


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If lupus went into remission & i no longer needed methotrexate, would it likely cause leukopenia or not?

If lupus went into remission & i no longer needed methotrexate, would it likely cause leukopenia or not?

Lupus can cause leukopenia: Lupus can cause leukopenia. Methotrexate can cause leukopenia. So the reason you might have it depends on the rest of the manifestations of your lupus. Other reasons besides Methotrexate lupus can also cause leukopenia. Thus your evaluation would try to clarify all of this. ...Read more

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Is it fairly common or possible 2have mostly negative lab workup with lupus. I have lupus & only abnormal labs is high +ANA and occassional leukopenia?

Is it fairly common or possible 2have mostly negative lab workup with lupus. I have lupus & only abnormal labs is high +ANA and occassional leukopenia?

Diagnostic criteria: Diagnosis of lupus requires meeting multiple criteria. Please consult this site for information on these. http://lupusresearchinstitute.org/lupus-facts/lupus-diagnosis ...Read more

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If lupus went into remission & person no longer needed methotrexate, would methotrexate likely cause leukopenia (in someone with normal higher wbc)?

If lupus went into remission & person no longer needed methotrexate, would methotrexate likely cause leukopenia (in someone with normal higher wbc)?

see details: The question does not make sense. Leukopenia is a side effect of Methotrexate but is commonly seen in lupus patients who never receive this medication. It can persist even when the disease is otherwise quiet. ...Read more

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Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd lupus.Possible w/normal labs?

Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd  lupus.Possible w/normal labs?

Lupus: Seems consistent with SLE . Need Rheumatologist follow up and specific anti double stranded DNA and other labs. SLE affects your kidney and can cause pericarditis. Immediate follow and management is helpful. ...Read more

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Could undiagnosed lupus lead to complications with needing multiple abd. Surgies..Body attacking itself?

Could undiagnosed lupus lead to complications with needing multiple abd. Surgies..Body attacking itself?

Maybe : Lupus, which is an autoimmune disorder, usually affects joints and skin but can have affect internal organs as well as blood vessels. Vasculitis, which involves blood vessel inflammation, is one way in which it can affect many orgran systems at once and lead to serious complications. If there is concern of lupus a thorough history, exam and diagnostic workup should be done to confirm. ...Read more

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Why was I diagnosed and then undiagnosed with lupus? Is my doctor incompetent?

Why was I diagnosed and then undiagnosed with lupus? Is my doctor incompetent?

See details: How can anyone possibly answered that question without knowing your entire history and having access to all of your lab results.See a rheumatologist if you have not done so already. If you are concerned, get a second opinion. ...Read more

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Doctors thinking lupus, still undiagnosed. Took Medrol (methylprednisolone) pack, symptoms got better. Finished pills, numbness spreading and new pains. Why? Normal?

See below: Corticosteriods will make all pain go away, but these are not be used for just any pain. They are reserved for certain conditions such as autoimmune diseases because of the extensive side effects that these medications have. ...Read more

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I have undiagnosed lupus. We still take tests but i show many signs. I have recently noticed some new bumps on my forearm that are clustered together. I also have one on my neck and one on my breast.

I have undiagnosed lupus. We still take tests but i show many signs. I have recently noticed some new bumps on my forearm that are clustered together. I also have one on my neck and one on my breast.

Lupus?: Why do you think it is lupus? Have you consulted with a rheumatologist? If so and "many tests were done" and it is still "undiagnosed" then it most likely not lupus and there is something else going on. If you have not seen a rheumatologist, then it is time to do so and to trust the advice they give you. ...Read more

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