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Doctor insights on: Uncommon Causes Of Elevated Thyrotropin Receptor Antibodies

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I just got my thyroid test and noticed my thyroglobulin Ab <20 and Peroxidase =201.. TSH receptor antibody 1.6 .. what does that signify ??

I just got my thyroid test and noticed my thyroglobulin Ab <20 and Peroxidase =201.. TSH receptor antibody 1.6 .. what does that signify ??

See your physician: You don't tell us what your thyroid function tests showed. You have autoantibodies - antibodies that our immune system produces against our own thyroid gland. You probably have thyroid disease and see your current physician first. You may have to see an endocrinologist, a physician who specializes in the diseases of the endocrine system. ...Read more

Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more


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I have graves disease for 5 yrs. Why would my dr.Order thyrotropin recepttor antibodies just when I am startingto feel better?

I have graves disease for 5 yrs. Why would my dr.Order  thyrotropin recepttor antibodies just when I am startingto feel better?

Anti-thyrotropin: Autoimmune diseases are often caused by antibodies that bind to a self component. Binding to a receptor for a hormone could result in inappropriately stimulating that receptor into thinking that it had bound a hormone molecule and this could result in the same effect as if excess hormone was present. Following the antibody level may be helpful in monitoring the activity of the disease. ...Read more

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What can cause high thyroid antibodies with normal tsh?

What can cause high thyroid antibodies with normal tsh?

Thyroid antibodies: Hashimotos disease - its an autoimmune disorder causing thyroid inflammation. An ultrasound should be performed to detect thyroid nodules. It can cause thyroid dysfunction ie TSH abnormalities over time. ...Read more

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Dx'd hypothyroid (TSH 28,negative antibodies) at 10y/o and on Levothyroxine since. Tested again and still neg antibodies. What could be cause of hypo?

Dx'd hypothyroid (TSH 28,negative antibodies) at 10y/o and on Levothyroxine since. Tested again and still neg antibodies. What could be cause of hypo?

Many possibilities: Hypothyroidism is very common but in most cases the cause isn't known. There are many possible causes.There are genetic tendencies and it's also related to iodine deficiencies and exposure to many environmental toxins including fluoride, BPA, pesticides, a diet high in goitrogenic foods etc. It is difficult to determine in an individual case. See http://tinyurl.com/p4p3fvj & my comment: ...Read more

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What causes Hashimotos? I only found out I have it cause I had post partum thyroiditis. One of the antibodies was slightly positive. TSH normal.

Autoimmune: This is considered an autoimmune disorder and eventually most will end up with low thyroid function. However the antibody titers , when the disease is active, should be more than slightly positive. ...Read more

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Tsh now 9.25, (was 31.9 in feb2013 when discovered). Thyroid peroxidase antibody lev 16. Does this mean hasimoto's is the cause of my hypothyroidism?

Tsh now 9.25, (was 31.9 in feb2013 when discovered). Thyroid peroxidase antibody lev 16. Does this mean hasimoto's is the cause of my hypothyroidism?

Improving: The lower TSH means that your thyroid function is under better control. It also appears likely that the problem is related to hashimoto's ...Read more

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Freezing hands, stiff fingers TSH 4.44 Free T4 1.38, negative all antibodies- is thyroid cause?

Freezing hands, stiff fingers TSH 4.44 Free T4 1.38, negative all antibodies- is thyroid cause?

Not thyroid: Hi. Your freezing hands and stiff fingers are not due to a disorder of thyroid function. Your thyroid function is normal. ...Read more

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TSH very low, thyroid nodules stable, endo doesn't know why, T3-4 normal neg antibody, what could be cause? Cea is 5.9

TSH very low, thyroid nodules stable, endo doesn't know why, T3-4 normal neg antibody, what could be cause? Cea is 5.9

Toxic nodular goiter: The fact that your TSH level is low is consistent with overactive thyroid even if the T3 (liothyronine) & T4 are Normal. If your TSH is below 0.10 mIU/ML I suggest you start on Antithyroid medications. ...Read more

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24 yr male with 60 kg, 5.5" tall, high anti-TPO antibodies..And a slightly elevated tsh.. Normal t3and t4..Not gaining weight.. Shd i start thyroxine?

24 yr male with 60 kg, 5.5" tall, high anti-TPO antibodies..And a slightly elevated tsh.. Normal t3and t4..Not gaining weight.. Shd i start thyroxine?

Hard call: Different endocrinologists will offer you different opinions. Staying trim like you are now is of course good. The question is whether your hashimoto's (which i suspect you have -- does your physician?) is slipping into hypothyroidism; only a minority do -- and if so, whether you want to take a bit of thyroxine perhaps as an experiment. Talk with yourdoctor & perhaps a 2nd opinion. Good luck. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more