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Doctor insights on: Types Cholestatic Liver Disease

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Can liver disease cause cholestasis?

Can liver disease cause cholestasis?

Sure, but...: Liver disease comes in many varieties and manifestations: cholestasis (either intrahepatic or extrahepatic) with jaundice; infiltrative (like fatty liver, amyloidosis); fibrotic (trending toward cirrhosis); congestive (blood backs up into the liver); ischemic; shock injury; toxic (either metabolic or drug-related); hepatitis (infectious or otherwise, the liver cells are sick); familial; cancer... ...Read more

Dr. Andrew Berry
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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How are alcoholic liver disease and viral hepatitis different?

How are alcoholic liver disease and viral hepatitis different?

Different causes: One is caused by alcohol and the other is caused by a virus which infects the liver, hepatitis b and c are the most common causes of chronic viral hepatitis. As both of these affect and damage the liver they may have similar symptoms such a jaundice and evenually cirrhosis. The treatment however would be different. Having a viral hepatitis and drinking would speed the progression of the damage. ...Read more

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What differentiates primary biliary cirrhosis from other types of cirrhosis?

What differentiates primary biliary cirrhosis from other types of cirrhosis?

Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring). Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read more

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Symptoms of liver disease?

Symptoms of liver disease?

Multiple symptoms: Liver disease has a multitude of symptoms. In the early phases it can be nonspecific like tiredness, lack of appetite ; energy, distaste for cigarettes, yellowish discolouration of eyes ; urine. With increasing loss of liver function, 1) fluid retention (belly/ankle swelling, 2) mental changes(confusion), 3) bleeding from the mouth or rectum, on in the skin. Hope this helps. ...Read more

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What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

This sounds serious: To translate, you have liver cell damage and scarring (cirrhosis), which caused abnormally elevated portal vein pressures which caused venous distention in esophagus (varices). You also developed fluid in abdominal cavity, because of the high portal vein pressure. This imaging study is showing advanced stage of liver disease. You must get a specialist to treat you. ...Read more

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Can lupus cause non-alcoholic fatty liver?

Can lupus cause non-alcoholic fatty liver?

Autoimmune hepatitis: Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Both entities can occur together when respective risk factors for both exist. ...Read more

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How serious a disease is non alcoholic fatty liver disease?

How serious a disease is non alcoholic fatty liver disease?

Read on: Read this short article: 1.https://www.kaushikmd.com/fatty-liver-on-a-rise-with-diabetes-and-obesity-epidemics/

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Pathophysiology of liver cirrhosis?

Pathophysiology of liver cirrhosis?

See below: Scar tissue in the liver as a result of different kinds of injuries. The significance is related to the chronicity for the injury and especially whether the injury is ongoing. ...Read more

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What's parenchymatous liver disease?

What's parenchymatous liver disease?

Liver Disease: The cells of the liver are called the parenchymal cells and make up the bulk of the liver. Therefore, this means that you have disease of the liver cells. Other cells in the liver include the bile duct cells (cholangiocytes), white blood cells (Kupffer cells), and storage cells (stellate cells). ...Read more

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What percentage of wilson's disease patients need liver transplants? 

What percentage of wilson's disease patients need liver transplants? 

Wilson and transplan: Roughly , about 30 % of patients. These are patient unable to tolerated the quelation therapy and develope neuropsyquiatric symptoms . Hope this help. ...Read more

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Can Celiac disease cause very high liver enzymes?

Depends!: Elevated liver enzymes can be due to a number of different conditions. They can even be elevated temporarily for no reason, & fall to normal the next time it is checked. Are you on any meds? Do you feel bad? There isn't enough info to give you a decent answer. Give a little more history, and add any meds or other medical problems that you have in your health history and it will help us answer ...Read more

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What is fatty liver disease?

What is fatty liver disease?

See below: Fatty liver is essentially the abnormal deposition of fat in the liver. It can lead to inflammation and ultimately cirrhosis. The causes include alcohol, non-alcoholic fatty liver and medications. Non-alcoholic fatty liver is the most common and is related to obesity, high triglycerides, diabetes and genetic predisposition. ...Read more

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Is non alcoholic fatty liver disease reversible?

Is non alcoholic fatty liver disease reversible?

NAFLD: Yes. Usually with weight loss through exercise and diet. Certainly should avoid other insults to the liver with this (ie alcohol). ...Read more

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What are signs of fatty liver disease?

What are signs of fatty liver disease?

Abnormal LFTs: there's NAFLD (nonalcoholic fatty liver disease) which is just fat in the liver, and more of it than usual - and NASH (nonalcoholic steatohepatitis) which is when that fat gets inflamed. the latter if not controlled, can lead to cirrhosis over time. Signs are typically elevated ALT (more so than AST) and increased echogenicity on ultrasounds. often associated with 'metabolic syndrome'. ...Read more

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How are celiac disease and autoimmune hepatitis different?

How are celiac disease and autoimmune hepatitis different?

Totally different: While both are autoimmune diseases, celiac is basically a GI disease characterized by a sensitivity to wheat (gluten) and hepatitis is characterized by inflammation involving the liver. ...Read more

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Dr. Anne Larson
1,604 doctors shared insights

Liver Diseases (Definition)

Liver disease = hepatic disorder = condition associated with decreased ...Read more