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Doctor insights on: Tylenol Pm Vs Benadryl For Sleep

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Dr. Heidi Fowler
4,988 doctors shared insights

Sleep (Definition)

Sleep is a topic that involves concepts such as how long it takes to fall asleep, how many times one wakes up at night, how many hours one sleeps at night, sleep stages, ...Read more


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I took Tylenol pm 8 hrs ago and didn't sleep. Can I take .0.5 mg of a xanax now to help me sleep?

I took Tylenol pm 8 hrs ago and didn't sleep. Can I take .0.5 mg of a xanax now to help me sleep?

Xanax: If you haven't taken any other benzodiazepines (like valium, ativan, klonopin) and the xanax is prescribed by your physician, then it should be fine to take 8 hours after the Tylenol PM ...Read more

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Pain reliever pm with acetaminophen 500mg and sleep-aid diphenhydramine hci 25mg ?

Pain reliever pm with acetaminophen 500mg and sleep-aid diphenhydramine hci 25mg ?

Question?: What is your question? Typically the pm pain relievers contain an antihistamine to promote sleep. But you may be groggy in the morning when you wake up. If you do not need pain relief try to avoid them, too much tylenol (acetaminophen) can have very bad side effects. Also please take only infrequently, never on a continuous basis. If sleeping is a problem, talk to your physician. ...Read more

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Can you take Allegra D and Tylenol PM together?

Can you take Allegra D and Tylenol PM together?

Yes you can, however: if you are taking the tylenol pm to help you sleep, it might not work if you are taking the allegra-d 24 hours, if you are taking the allegra-d 12 hours in the morning so the tylenol pm would work at night. good that you asked, always exercise caution with multiple medications ...Read more

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
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Can I take mucinex fast max night time cold and flu with Tylenol pm?

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
Can I take mucinex fast max night time cold and flu with Tylenol pm?

Better not: Both combinations contain almost similar ingredients, stick to only one, and read the labels carefully. The mucinex combo has a decongestant as well, so be careful if you have high blood pressure, wish you well ...Read more

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Could i take tylenol (acetaminophen) 3 with pain pills pm that has diphenhydramine?

Could i take tylenol (acetaminophen) 3 with pain pills pm that has diphenhydramine?

Med interaction: Tylenol (acetaminophen) 3 has a morphine class of medicine, which can make some people sleepy or depress the body's functions: decreased breathing, slow down the gut and decrease the heart rate. This is especially true in large amounts. If you add diphenhydramine, another sedating medication, could be detrimental if the dose is too high for you. ...Read more

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I took 2 tylenol (acetaminophen) pm 18 hours ago. The box says not to take meds containing diphenhydramine for 24 hours. Is it safe to take clearquil before 24 hrs?

Diphenhydramine: Which qlearquil formulation do you want to use? At any rate , read the labels carefully as you did with tylenol (acetaminophen) pm, the idea is not to exceed a total dose of diphenhydramine of 300 mg/24 hours,so if you took 2 tylenol (acetaminophen) pm18 hrs ago, that has 50 mg of diphenhydramine,you should be fine, the label on the tylenol (acetaminophen) was meant to protect you from overdosing if you took full dose of it besides other meds ...Read more

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I've been taking ten Tylenol PM a night for at least two weeks, am I in danger?

I've been taking ten Tylenol PM a night for at least two weeks, am I in danger?

Acetaminophen: https://www.tylenol.com/safety-dosing/usage/dosage-for-adults
Even the manufacturers of Tylenol do not recommend taking more than six tabs in a 24 hour period due to the risk of liver injury. This was recently *lowered* from the maximum of eight tabs. ...Read more

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I think I took 4 Tylenol pm pills instead of 2 when I was getting ready for bed. Is this ok?

I think I took 4 Tylenol pm pills instead of 2 when I was getting ready for bed.  Is this ok?

Tylenol overdose: It depends on when you had your last dosage, the current state of your liver, and the number of milligrams you took. 4 Grams within 24 hours is concerning. If you feel weak, nauseous, and have abdominal pain you should definitely get yourself evaluated as soon as possible. You should follow up with your physician regardless. Following directions as prescribed is crucial to preventing an overdose. ...Read more

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I just took 1 500mg Tylenol PM and about an hour later I took 30mL of NyQuil. Am I at any serious health risk. It's the only time I've done so.

I just took 1 500mg Tylenol PM and about an hour later I took 30mL of NyQuil.  Am I at any serious health risk.  It's the only time I've done so.

Nothing serious: Tylenol is quite safe up to 2 grams per day. So you should not have any serious after effects. Be careful and have your m,ind focus on the medicines when you take any pills! ...Read more

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Recently found out I likely have high histamine. I had a reaction to Advil&Aleve. Would Tylenol also cause a histamine reaction? My nose and throat became very blocked/congested. Took Benadryl which helped. But throat feels like golf balls In my thrt

Recently found out I likely have high histamine. I had a reaction to Advil&Aleve. Would Tylenol also cause a histamine reaction? My nose and throat became very blocked/congested. Took Benadryl which helped. But throat feels like golf balls In my thrt

Aspirin-intolerance?: I presume that you either have nasal congestion/asthma or an anaphylactic reaction to NSIDS in general. The reactions are not considered primarily a histamine-mediated one. Tylenol or Cox-2 inhibitors should be tolerated. If Benadryl helps your symptoms, you should consult an allergist to find out what can be done to make you feel better. ...Read more

Dr. John Chiu
1,045 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more