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Doctor insights on: Tylenol Pm Extra Strength Medication

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Dr. Heidi Fowler
1,444 doctors shared insights

Tylenol (Definition)

Acetaminophen (tylenol) is a non-steroidal anti-inflammatory which is a ...Read more


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I've been taking ten Tylenol PM a night for at least two weeks, am I in danger?

I've been taking ten Tylenol PM a night for at least two weeks, am I in danger?

Acetaminophen: https://www.tylenol.com/safety-dosing/usage/dosage-for-adults
Even the manufacturers of Tylenol do not recommend taking more than six tabs in a 24-hour period due to the risk of liver injury. This was recently *lowered* from the maximum of eight tabs. ...Read more

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I think I took 4 Tylenol pm pills instead of 2 when I was getting ready for bed. Is this ok?

I think I took 4 Tylenol pm pills instead of 2 when I was getting ready for bed.  Is this ok?

Tylenol overdose: It depends on when you had your last dosage, the current state of your liver, and the number of milligrams you took. 4 Grams within 24 hours is concerning. If you feel weak, nauseous, and have abdominal pain you should definitely get yourself evaluated as soon as possible. You should follow up with your physician regardless. Following directions as prescribed is crucial to preventing an overdose. ...Read more

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Can I take ambien and Tylenol pm?

Can I take ambien and Tylenol pm?

Sedation: The Tylenol PM contains antihistamine which can interact with the Ambien: not a good idea. ...Read more

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Can I take Tylenol PM the night before a colonoscopy?

Can I take Tylenol PM the night before a colonoscopy?

Fine: should be fine as long as you have no condition that is adversely affected by TYLENOL such as either allergy or liver disease. H Robert Silverstein M.D. FACC ...Read more

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I just took 1 500mg Tylenol PM and about an hour later I took 30mL of NyQuil. Am I at any serious health risk. It's the only time I've done so.

I just took 1 500mg Tylenol PM and about an hour later I took 30mL of NyQuil.  Am I at any serious health risk.  It's the only time I've done so.

Nothing serious: Tylenol is quite safe up to 2 grams per day. So you should not have any serious after effects. Be careful and have your m, ind focus on the medicines when you take any pills! ...Read more

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I drank a beer and a bit of fireball at about 10/10:30, and took 2 Tylenol pm at 12:30, am I going to have to go to the doctor?

I drank a beer and a bit of fireball at about 10/10:30, and took 2 Tylenol pm at 12:30, am I going to have to go to the doctor?

Fireball whiskey: Drinks? Don't have any idea of how much liquor you drank? Are you feeling ill in any manner? If you drank one 12 ounce beer & 1 shot of whiskey- then took 2 tylenol than you will likely be fine. Did you drink massive amounts of alcohol? Perhaps you could resubmit with more info- there isn't enough here to be able to say. ...Read more

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
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Can I take mucinex fast max nighttime cold and flu with Tylenol pm?

Dr. Al Hegab Dr. Hegab
2 doctors agreed:
Can I take mucinex fast max nighttime cold and flu with Tylenol pm?

Better not: Both combinations contain almost similar ingredients, stick to only one, and read the labels carefully. The mucinex combo has a decongestant as well, so be careful if you have high blood pressure, wish you well ...Read more

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Can you take Allegra D and Tylenol PM together?

Can you take Allegra D and Tylenol PM together?

Yes you can, however: If you are taking the tylenol pm to help you sleep, it might not work in case you are taking the allegra-d 24 hours, but if taking the allegra-d 12 hours in the morning then the tylenol pm would work at night.

Good that you asked, always exercise caution with multiple medications ...Read more

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I took Tylenol pm 8 hrs ago and didn't sleep. Can I take .0.5 mg of a xanax now to help me sleep?

I took Tylenol pm 8 hrs ago and didn't sleep. Can I take .0.5 mg of a xanax now to help me sleep?

Xanax: If you haven't taken any other benzodiazepines (like valium, ativan, klonopin) and the xanax is prescribed by your physician, then it should be fine to take 8 hours after the Tylenol PM ...Read more

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I had 2 Tylenol extra strength @ 6:30 pm yesterday 7/28 I took 2 more @ 1:10 a.m 7:29 Is it safe to take 2 Tylenol Extra Strength Rapid release now?

Likely ok: If this is for a day or two, the dose is probably ok. Do note that any dose higher than that may cause liver problem for some people. Long-term intake of tylenol is not a good idea however due to the liver issue. ...Read more

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How long should you wait to drink alcohol after taking the recommended dose of extra strength tylenol (acetaminophen) pm?

How long should you wait to drink alcohol after taking the recommended dose of extra strength tylenol (acetaminophen) pm?

Tylenol (acetaminophen) and Alcohol: I may be going against the grain here, but please if you are drinking do not use any product with acetominophen or tylenol (acetaminophen).

I have seen too much liver damage from this over the counter medication, especially those with other diseases or who drink regularly.

Tylenol is toxic to the liver. And this toxicity can increase with ongoing use of both of these products: alcohol and tylenol (acetaminophen). ...Read more

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I had 4 xtra strength tylenol (acetaminophen) pm?

I had 4 xtra strength tylenol (acetaminophen) pm?

Unsure of question: But it is not recommended to take this much. While you most likely will be safe, you will be sedated and can even cause liver damage if you are susceptible. Make sure you do not do anything that you may be unsafe if sedated and follow recommended dosing from now on. Hope that helps! ...Read more

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I took one Tylenol (acetaminophen) regular strength around 10am, the I took two advils at 5 pm, in the evening I had 2 glesses of wine, can I take more advil?

I took one Tylenol (acetaminophen) regular strength around 10am, the I took two advils at 5 pm, in the evening I had 2 glesses of wine, can I take more advil?

Ibuprofen: I'm not sure how many hours ago you took your last ibuprofen. You can repeat the dose every 4 to 6 hours. Why are you taking the Tylenol (acetaminophen) and Advil? Ask another question with more details on why and we can help more. ...Read more

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Took one regular strength Tylenol (acetaminophen) at 2:30 pm. I drank one glass of wine at 11:00pm. Is that going to damage my liver?

Took one regular strength Tylenol (acetaminophen) at 2:30 pm. I drank one glass of wine at 11:00pm. Is that going to damage my liver?

Unlikely: As you are astutely aware, mixing alcohol and Tylenol (acetaminophen) is never a good idea (Tylenol (acetaminophen) (acetaminophen) is the worst choice for hangovers). Liver toxicity of each is exponentially worse when mixed. If you are healthy (no baseline liver dysfunction), then I would not worry about these levels of ingestion. Stay vigilant! ...Read more

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Can I take extra strength Tylenol rapid release with melatonin?

Read label...: If the formulation you are referring to has diphenhydramine in it, be careful about excess sedation when taking it with melatonin. If it only has acetaminophen in it, then do not exceed 3 grams in a 24-hour interval. Read the instructions to determine how much to take in a single dose. Good luck! ...Read more

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Can I take Tylenol extra strength with fioricet if I don't exceed 3000/24 hours?

Be cautious: I would try to avoid taking up to 3000mg of tylenol on a regular basis regardless of what source. While 3000mg/24 is an accepted dosing amount. The potential for cumulative toxicity is still significant especially if you take it regularly. Also, be very cautious if you have liver problems, consume alcohol or take other medications metabolized in the liver.
Hope that helps. ...Read more

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Can you take reactine and extra strength Tylenol together?

Yes: Drugs. Com drug interaction checker showed no interactions between Reactine (Cetrizine) and Tylenol. See: https://www.drugs.com/interactions-check.php?drug_list=569-0,11-12 ...Read more

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I took 4 extra strength tylenol (acetaminophen) In 4 hours is that ok?

Probably OK: Extra strength Tylenol (acetaminophen) are 500 mg, so 4 of them is 2000 mg. The usual safe recommended maximum daily dose is 3000 mg in 24 hours. If there is underlying liver or kidney disease or other medications that interact, even 2000-3000 mg can be too much. The other issue to consider is the need for Tylenol (acetaminophen). If there is a new pain that needs to be evaluated, see your doctor. ...Read more

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Is it ok to take a tylenol (acetaminophen) 3 and an extra strength together?

Should be fine : That would be 300 mg Acetaminophen from the tylenol (acetaminophen) #3 and 500 mg (650 mg old) from the es tyl, for a total of 800 to 950 mg of tyl. As long as the tyl #3 was prescribed by your doctor and as long as you don't excess 3, 000 to 4, 000 mg of tylenol (acetaminophen) per day, this should not cause any problems. Must have normal kidney/liver function and avoid alcohol and other liver toxins. ...Read more

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Can I take 3 tylenol (acetaminophen) extra strength in one dose?

Not good idea: You should follow instructions on the bottle and do not take more than 4,000 grams in a 24-hour period. It is harmful to the liver. ...Read more

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How long does it take Tylenol (acetaminophen) extra strength to work?

Acetaminophen: Onset of action of oral acetaminophen is less than one hour. Duration of action is about 4-6 hours. Please be careful with this drug. Never take more than 3000 mg per day. Take even less if you have any liver problems. Never combine this or any prescription medication with alcohol. The most common form of attempted suicide in the U.S. is intentional acetaminophen overdose. Be careful, please. ...Read more

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Can I take 3 tylenol (acetaminophen) extra strength at the same time?

Only 2: For tylenol extra strength (acetaminophen 500 mg/tablet), you can take 1-2 tabs/caps every 4-6 hours as needed. Maximum of 6 tabs or caps/24h. Do not exceed 1 g/4h and 4 g/day from all sources. ...Read more

Dr. Alvin Stein
2,106 doctors shared insights

Acetaminophen (Definition)

Acetaminophen (tylenol) is a non-steroidal anti-inflammatory which is a ...Read more