Doctor insights on:
Tumor Necrosis Factor Banana
Stimulate reaction: Tumor necrosis-alpha , ( tnf) also known as cachexin or cachectin is a cytokine mainly secreated by macrophages stimulates the acute phase of inflamation. Tnf regulates the immune cells, performs varieties functions as pyrogen ( causing fever ), regulates cell proliferation, differentiation, apoptosis ( cell death or suicide ) , in lipid metabolism, in coagulation of blood etc. ...Read more
"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more
Yes: Vascular endothelial growth factor (vegf) is a substance that cells produce which helps them recruit the growth of new blood vessels. Blood vessels are essential in bring normal cells and cancer cells the oxygen and nutrients they need to keep growing. The growth of some types of cancer can be slowed or controlled by blocking vegf. ...Read moreSee 1 more doctor answer
Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis?
Perhaps: Certain chemo and radiation can cause avn. Certain cancers and disease can as well. It is best to discuss this with your oncologist or internist. ...Read more
Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? .
Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read moreSee 1 more doctor answer
Bevasizumab or: Avastin (bevacizumab) vies with vascular endothelial growth factor. It's action interferes with development or growth of blood vessels needed by tumors. Causes incresed blood pressure and bleeding as leading toxicity. No obvious reason that it should influence tumor markers. ...Read more
Intravesicle meds: The treeatment of bladder cancer is based entirely on the extent of the mucosal invasion of muscle of the bladder. When the latter occurs surgery is required along with possible RT. When superficial it is managed by intra bladder chemo or BCG. ...Read moreSee 1 more doctor answer
Tumor necrosis: Factor (tnf) promotes the inflammatory response, which in turn causes many of the clinical problems associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis. These disorders are sometimes treated by using a tnf inhibitor. The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections, congestive heart ad others. ...Read more
Not at all: Fat necrosis is a result of trauma to the breast, sometimes so minor that you may not even remember the event. Lump develops but usually there is a history of black and blue bruising for a short period of time. Generally, the lump decreases in size over a period of time and disappears entirely, though this may take several weeks or months. There is no risk of cancer. ...Read moreSee 1 more doctor answer
For certain cancers: Circulating tumor cell count is done and quite useful to see the response of treatment given for certan type of metastatic cancers only -i, e, metastatic breast cancers, prostate, and colon cancer. Not indicated / used for other type of cancers and not used for earlier stage of cancer. ...Read moreSee 1 more doctor answer
Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read moreSee 1 more doctor answer
Yes: Vascular endothelial growth factor (vegf) is a substance that cells produce which helps them recruit the growth of new blood vessels. Blood vessels are essential in bring normal cells and cancer cells the oxygen and nutrients they need to keep growing. The growth of some types of cancer can be slowed or controlled by blocking vegf. ...Read more
Possible: Possible but highly unlikely.Get a more detailed answer ›
Is a neurofibroma tumor 2.5 CM in size positive for s100, pgp9.5, NSE, factor XIIIa, CD 34, desmin, and SMA cancer? Negative for CD68.
With inoperable non-small cell lung cancer, if there's a targetable genetic mutation (EGFR etc) can it be treated at stage 3A? Alongside chemo/radio?
Yes: EGFR mutations (exon 19 or 21) in lung cancer are more common in non-smokers, Asians, and women. Upfront use of an oral tyrosine kinase inhibitor (TKI) results in better progression-free survival than chemotherapy when these mutations are present, although overall survival is not different. Discuss options with your oncologist. ...Read moreSee 1 more doctor answer
Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.
Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more
Does the term: Inflammatory cytokine help? It is not specific to any disease but may be a pathway to appetite loss, it's also called cachexin, and a pathway involved in cellular and organ injury...Including radiation, and possibly a cause of lung injury from xrt. It is not of itself painful. ...Read more
Increased risk.: Smoking introduces many very carcinogenic compounds into the bloodstream, which is filtered by the kidney. These carcinogens, along with the decreased tissue oxygenation caused by smoking, is theorized to increase the risk of renal cell carcinoma. A meta-analysis of 24 studies (hunt, int j cancer 114:101-108, 2005) showed this significantly increased risk, & it is considered causal by the ussg. ...Read moreSee 1 more doctor answer