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Doctor insights on: Tumefactive Multiple Sclerosis

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Multiple sclerosis = demyelination?

Multiple sclerosis = demyelination?

Characteristic: Demyelination refers to damage to the coverings of the nerves in the brain and spinal cord, and is very characteristic of the inflammatory process that occurs in ms. This can also occur in children with hereditary leukodystrophies, and can be associated with acquired neurological disorders. The disease modifying drugs in MS are designed to control demyelination and many work well. ...Read more

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Dr. Stephen Scholand
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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Who discovered multiple sclerosis?

Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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What disease might mimic multiple sclerosis?

What disease might mimic multiple sclerosis?

Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read more

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Is multiple sclerosis fatal?

Is multiple sclerosis fatal?

Not usually: Ms is a chronic neurological condition, characterized by episodes of neurological disability of variable severity and recovery. A minority of inidividuals can have a very aggressive course, and become so disabled that they are at risk of secondary medical complications which may be fatal. There are subtypes of MS which are so aggressive that a fatal outcome can happen. Fortunately these are rare. ...Read more

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What symptoms of ms multiple sclerosis ?

What symptoms of ms multiple sclerosis ?

Variable: Please consult this site for information on early symptoms of MS http://www.webmd.com/multiple-sclerosis/guide/multiple-sclerosis-symptoms Wish you good health. ...Read more

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Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Say what???: This question is confusing! optic neuritis (abbreviated on) is one of many symptoms of ms and results from inflammation in one or both optic nerves. It is one of the most common symptoms of ms and typically causes eye pain and decreased vision in one eye. It does not typically cause complete blindness. Multiple sclerosis (ms) is an autoimmune disorder of the center nervous system. See below. ...Read more

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Is multiple sclerosis preventable?

Is multiple sclerosis preventable?

No: Population studies have suggest that mononucleosis in adolescence, smoking, and possibly childhood obesity are risks for developing ms. However ms is a complex variable disease requiring genetic predisposition along with some environmental trigger(s), possibly influenced by hormones, immune system priming from certain infectious agents. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

What is MS: Multiple sclerosis is an autoimmune disease that affects the brain, spinal cord, and / or optic nerves. It may cause attacks of symptoms or follow a progressive course. It may affect different areas of the these body parts at different times over many years. It may be either aggressive or benign. ...Read more

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What multiple is sclerosis? What multiple is sclerosis?

What multiple is sclerosis? What multiple is sclerosis?

Multiple : Multiple sclerosis is an autoimmune disease that affects the protective covering around nerves in the spinal cord and brain. I've attached a few good websites below that discuss ms in much more detail. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

Multiple Sclerosis: http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001747/.

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

Multiple sclerosis : Multiple sclerosis is a neurological disorder in which the brain and spinal cord become the target of our own immune system. The myelin, important brain substance that facilitates brain cell communication, gets damaged in multiple areas over time as result of this inflammatory response. Patients symptoms may vary based on the area affected by the inflammation or demyelination. ...Read more

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What is multiple sclerosis?

Autoimmune condition: It is a condition where your own immune system attacks the sheaths (myelin) which covers your nerve fibers. Common symptoms include weakness in muscles due to slow/ damaged nerve conduction. Lowering Inflammation in your body via diet, stress reduction, anti-inflammatory supplements may delay, stabilize and improve the condition. ...Read more

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Common symptoms of multiple sclerosis?

Common symptoms of multiple sclerosis?

Varies, but often: The disease can present with loss of vision in one eye, electrical tingling on bending the neck, unexplained imbalance or falling, leg weakness and/or spasticity, bladder incontinence, fatigue, double vision, and problems with intellectual function. This can be isolated or grouped, and in 85% if pts symptoms come on rapidly and slowly remit, i.e., relapsing-remitting ms. Start rx asap. ...Read more

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Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Neither of them: Neither of these conditions is a condition of the neuroglia. To some extent, glial cells are involved in the repair of damage that occurs in MS. Myasthenia is a condition that occurs at the junction of the nerve and muscle, no glia cells are present there. ...Read more

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What causes tuberous sclerosis?

Genetic mutations: These people have a genetic mutation at one of two loci TSC1 or TSC2 (hamartin and tuberin). A second mutation in a particular cell results in creation of a tumor. No two TS patients are alike and the severity of the illness varies tremendously. It's not curable, but it's often manageable. Best wishes. ...Read more

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MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

Concern for MS, But: Phyllis, talk to the doctor who ordered the MRI, since he/she can interpret the MRI in the context of the symptoms that brought you to the clinic. In some cases, periventricular white matter lesions are the result of migraines, old head trauma, neuron migration issues, or MS. It is hard to know from just a description of the MRI which is the cause. Good Luck and Stay Healthy! ...Read more

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Best multiple sclerosis medications?

Interferons ? : There is no best medication , some would suit the patient better than others but interferons are the most widely used for prevention of attacks. ...Read more

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What are signs of multiple sclerosis?

Many: Ms can present with a host of physical findings including optic neuritis, unilateral weakness and numbness, a band-like sensation around your chest or abdomen, hearing loss, gait ataxia, slurred speech, urinary incontinence, bilateral upper extremity/lower extremity weakness. Typically the initial presentation in the young may be a single symptom (optic neuritis), however hemiparesis is seen. ...Read more

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Any docs familiar with Tumefactive Multiple Sclerosis? Ever seen a persistently enhancing lesion? 4cm lesion 5yrs enhancement. RR symptoms. 5 OCB.

Any docs familiar with Tumefactive Multiple Sclerosis? Ever seen a persistently enhancing lesion? 4cm lesion 5yrs enhancement. RR symptoms. 5 OCB.

Generic response: "Tumefactive" lesions are not uncommon in MS, and may be associated with even very potent medications. From your description, would presume your diagnosis is correct for R/R MS, but the lesion in question may be a co-morbidity, such as a vascular malformation, a brain glioma, or even a nidus of infection, such as abscess. Need to see your neurologist and go through careful and thorough testing. ...Read more

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What are the dangers, if any, of taking cycles or "gear" for bodybuilding if that person had multiple sclerosis? I'm just curious.

Not simple: Bodily temperature elevation, from vigorous exercise, may result in a pseudo exacerbation, with amplification of prior symptoms which can reverse with cooling. But exercise is of value for ms patients, just needs to be paced. Also, depending upon the patients debility, exercise should be designed to prevent harm secondary to weakness, or imbalance/incoordination. ...Read more

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Why are "family doctors" answering multiple sclerosis questions?! I have spotted inaccurate info being given. Only a neuro answer? 's

Part of a team: Your family doctor is usually the doc who makes the referrals and is often the one who helps treat complications, such as urinary tract infections, fatigue, associated injuries, medication reactions, and he/she keeps open the communication lines between different specialties. Coordination of medical care is critcal these days. ...Read more

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I'm scared I have multiple sclerosis?

Need to know more: Will really need to know more about what your symptoms are. Initially, you should discuss your concerns with your primary care physician. Then an appropriate a referral to a neurologist will allow a more definitive diagnosis for you.Multiple sclerosis is treatable at the present time with multiple medications and ensure an excellany quality of life. ...Read more

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What are the odds that I'm going to develop multiple sclerosis? How common is this?

What are the odds that I'm going to develop multiple sclerosis? How common is this?

Variable.: If you have identical twin with MS, about 30%, but if no relative and you live north of latitudes 39-42, could be as high as 1 in 545 in the general population. About 450,000 cases thought to be in USA, in a population over 300,000,000. ...Read more

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I recently diagnosed by multiple sclerosis, and I don't know what to do I'm afraid to take medication.

Multiple sclerosis : First, I wish you will get better and get over this disease, and that can't be achieved without specialists supervision, neurologists and other physicians, and taking medications prescribed according to your stage / severity of the disease, if questioning the diagnosis, get a second opnion. If really anxious / depressed seek psychiatric help, but don't just stay put, good luck ...Read more

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I've had numerous test done. Outcome sign of Multiple Sclerosis not active I'm 50 will it become active?

Yes it is possible: Disease can go into remission and then flare up. You have to look for the cause. We propose to treat causes of such chronic ailment. To learn more about how to treat the cause Please visit us www.ehacstl.com ...Read more

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Treatment of multiple sclerosis is for life or temporary taking s.c injection of betaferon?

Treatment of multiple sclerosis is for life or temporary taking s.c injection of betaferon?

Need chronically: Some advice, there are pills available, but where you live, might be tough to get. Nonetheless, do not miss your injections, and add Vitamin D-3 about 5000-10000 units per day. We do not have a clear idea when to stop the MS meds, and in those older patients who I have stopped, a few have had relapses. Stay tuned, drugs to be used differently are on the horizon. (even Lemtrada) ...Read more

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All test Negative. No multiple Sclerosis! Who or where can I go to find out why I'm having problems bending my leg. NO PAIN!!! ?

All test Negative. No multiple Sclerosis! Who or where can I go to find out why I'm having problems bending my leg. NO PAIN!!!
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Painless leg problem: I'm a bit confused. You state "No multiple Sclerosis!" but in your Clinical Findings: Conditions, you list "Multiple sclerosis". You also didn't describe where you're having painless difficulty bending your leg: hip? knee? ankle? My suggestion is to have your Family Doc refer you to Sports Med specialist, Rheumatologist, Orthopedic surgeon & even Neurologist esp if MS. Have u had EMG/NCV? Biopsy? ...Read more

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I have multiple sclerosis & the symptoms of diabetes are so similar how do I know if i'm a diabetic? My dr. Refers everything to multiple sclerosis.

I have multiple sclerosis & the symptoms of diabetes are so similar how do I know if i'm a diabetic? My dr. Refers everything to multiple sclerosis.

Easy: The test for diabetes is simple - it is just a blood test. It is important not to attribute everything you experience to ms. However, it is possible your doctor has already done some additional testing and has ruled-out diabetes. Many patients are not aware of all the tests that are run when they go to the lab and have blood drawn. Just ask your doctor. ...Read more

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Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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Could you cure multiple sclerosis?

No cure at this time: It is difficult to develop a cure when the cause of a condition is not fully understood. There seem to be several factors that contribute to the development of MS but there is no ONE gene or ONE virus that has been implicated as a direct cause. Rather, the interaction of genetic susceptibility and infectous and/or environmental factors seem to result in dysregulation of the immune system. ...Read more

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How is multiple sclerosis diagnosed?

Detective Work: No one diagnostic study can stand alone to conclusively diagnose ms. A neurologist must be a detective, hunting out clues from symptoms suggesting abnormal function in the brain or spinal cord white matter, of appropriate duration (greater than 24 hours) coupled with abnormalities on examination. Mri, spinal fluid, and certain blood tests. This information can help exclude MS mimickers. ...Read more

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What makes you get multiple sclerosis?

What makes you get multiple sclerosis?

Not fully understood: Multiple sclerosis is a very complex disease. There is a large collection of research identifying certain genes (most governing control of the immune system) as both increasing risk and potentially protective against MS (based on studies of populations). Environmental and hormonal factors may also play a role in individuals with a background genetic risk. ...Read more

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How is multiple sclerosis transmitted?

Genes: Ms has been shown to be associated with mutations in a number of genes, the majority of which appear to regulate the immune system. Among first degree relatives, the risk of ms is increased, but absolute risk is low. Other factors weigh in to the development and expression of this disease other than strictly genetic predisposition. ...Read more

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What is a legent for multiple sclerosis?

What is a legent for multiple sclerosis?

What is a legent?: Not sure what legent means. Some people ask about lesion, or legend, or ligand, are any of those what you mean? Feel free to ask again, asking questions is free. ...Read more

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How to know if I have multiple sclerosis?

How to know if I have multiple sclerosis?

??: Why do you inquire about this? A diagnosis of MS typically requires specialized testing performed by a neurologist. ...Read more

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What are some effects of multiple sclerosis?

What are some effects of multiple sclerosis?

Reputable resources: I suggest that my patients spend time exploring the following websites: NMSS.org MSAA.org You may also get information from the MS societies in the UK and Canada. Please understand that the phenotype of MS is highly variable. Some patients are seemingly unaffected and others are profoundly disabled. Do not assume that the person with MS will experience all of the symptoms you read about. ...Read more

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Dr. Bennett Machanic
1,448 doctors shared insights

Multiple Sclerosis (Definition)

A progressive disease that interferes with the functioning of the central nervous system and brain. Symptoms include numbness, impairment of speech and of muscular coordination, blurred ...Read more