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Doctor insights on: Tuberculosis Bone Disease

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Dr. Scott Lindquist
633 doctors shared insights

Mycobacterium Tuberculosis Infection (Definition)

Mycobacterium tuberculosis is an infectious organism that spreads by droplets coughed out by an infected person. Infection is established initially in lungs, but can spread within lungs & to other body parts, or can become latent, with reactivation occurring years to decades later. With effective treatment, it can be completely eliminated although drug resistant ...Read more


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What is infectious granuloma auch as tuberculosis verus cavitary lung cancer?

What is infectious granuloma auch as tuberculosis verus cavitary lung cancer?

Unclear question: Examination of the tissue by a pathologist is the gold standard for diagnosis. However, an apical cavitary lesion in the lung should be treated as tuberculosis, unless proven otherwise. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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Is brittle bone disease genetic?

Is brittle bone disease genetic?

Usually: Osteogenesis imperfecta is a disorder of brittle bones. There is an abnormality in collagen 1 function, and so you are not able to make bones or other connective tissue structures correctly. This is why people often have "blue sclera" because the collagen is abnormal. Most cases are genetic, but a new mutation (not inherited) can be seen (about 35%). ...Read more

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Crohn's disease & metabolic bone disease. Is there a relation?

Crohn's disease & metabolic bone disease. Is there a relation?

Yes: Yes, potentially by three mechanisms: first, a percentage of patients with Crohn's disease will have an inflammatory arthritic component to it that can affect the bones; second, patients with Crohn's can have malabsorption of some of the key nutrients that make bone string; and third, some of the medications used to treat Crohn's can impact bone health. Discuss with your doctor. ...Read more

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Which disease is deadlier: chronic bronchitis or kidney disease (stage 4)?

Which disease is deadlier: chronic bronchitis or kidney disease (stage 4)?

Kidney ds/more info: It is difficult to determine from the information provided. Stage 4 kidney disease is severe but most forms of chronic bronchitis can be managed. ...Read more

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Multilobulated pulmonary mass w/calcifications in left upper lobe. Neoplastic disease vs inflammatory/infectious process. rule out metastatic disease ?

Multilobulated pulmonary mass w/calcifications in left upper lobe. Neoplastic disease vs inflammatory/infectious process. rule out metastatic disease ?

In general...: IN GENERAL, a multilobulated mass is more likely malignant, one with calcifications is less likely. As in much else, size matters, with bigger being more worrisome. If you're smoker, more likely malignant, if from place of endemic TB or histoplasmosis, risk of chronic infection rises. You'll need to be evaluated by a pulmonologist, who will very likely recommend biopsy. ...Read more

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CT result-Thorax extensive mediastinal lympopathy with central caseating ,TB lymphopathy to consider skin,blood culture negative it is TB disease?

Caseating granulomas: This sounds like tuberculosis, but may conceivably be systemic fungal infection like Histoplasmosis, rarely lymphoma or sarcoidosis. In India this is probably TB and either should be treated empirically or wait for the results of the biopsied lymph nodes. Sounds as if your doctor is very astute and would heed their advice. Best wishes. ...Read more

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Can brittle bone disease be fatal?

Yes it could be: Some new born die during delivery because they have so many fractures during delivery. (osteogenesis imperfecta). ...Read more

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How can you differentiate primary malignant bone tumor from metastatic bone disease in x-ray?

Several ways: A primary bone tumor might have certain radiographic characterisitics that are different than metastatic bone disease. Multiple bone tumors strongly suggests metastases. The presence of a prior cancer also strongly suggests that a bone tumor is metastastic. ...Read more

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Brittle bone disease ..Advice any treatment?

Brittle bone disease ..Advice any treatment?

Symptom relief: There is no cure since it is a genetic disease, but regular weight-bearing exercise to prevent bone loss, a diet rich in calcium and vitamin d, and sometimes even vitamin supplements will help. Bisphosphonates are a group of drungs that can increase bone density, but they have side effects. ...Read more

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Sickle cell disease - is it curable with a bone marrow transplant?

Sickle cell disease - is it curable with a bone marrow transplant?

I do not know.: Most patients with sickle cell diseaes have a very benign manifestation of the diseas (trait) and they can live close to a normal life. E few percentage of this people has severe disease. I do not have experience with bone marrow transplant for sickle cell disease. ...Read more

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What is brittle bone disease called?

OI: Osteogenesis imperfecta. There are several types of the disease. Type 1 is mild disease. Type iii is the one in which people are most affected. Hope this helps. ...Read more

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Is aml cancer cured by getting bone marrow transplant?

Is aml cancer cured by getting bone marrow transplant?

Yes: It can be . In poor risk aml that is the only curative option albeit with risk of complications. Chance of cure is bw40-50 percent ...Read more

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Why avascular necrosis in sickle cell disease involve long bone only?

Why avascular necrosis in sickle cell disease involve long bone only?

The ends of : The long bones have the most tenuous blood supply, and thus are at the greatest risk. ...Read more

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Is Osteonecrosis an infectious disease?

Is Osteonecrosis an infectious disease?

No: Osteonecrosis is when part of the bone starts to die due to lack of blood flow and oxygen. It is not typically associated with an infectious disease, however in some bacterial joint infections osteonecrosis can occur. ...Read more

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Is arthritis a communicable disease?

Is arthritis a communicable disease?

Life: Nope. Not in general. There is a very rare form of arthritis, however, caused by disseminated gonorrhea. ...Read more

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Al Hegab
43 doctors shared insights

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more