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Doctor insights on: Trisomy X Syndrome

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Trisomy (Definition)

Ordinary chromosomal traits require a pair of chromosomes to determine the traits. Occasionally, as a mistake in cellular division, there is a tripling of one of the chromosomes. When these occur, they usually cause unpleasant, and sometimes deadly conditions in the inheritor of these traits (e.g. Down's). Many we do not know about as they are ...Read more


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Can you tell me how can the chromosomal conditions , trisomy x, xyy syndrome and turner syndrome differ?

Can you tell me how can the chromosomal conditions , trisomy x, xyy syndrome and turner syndrome differ?

Good online sites: Xxx and xyy have relatively little impact on those who have them and are usually incidental findings -- this is actually true despite the hoopla over xyy. I have three physician colleagues who have turner's xo and do fine. http://ghr.nlm.nih.gov/ is really good (thanks uncle sam). ...Read more

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Whats triple x syndrome?

Whats triple x syndrome?

Extra x: Triple x is a syndrome that affects females. It is an abnormal chromosome population with an extra x. It is detected by blood testing for chromosomes. It has mild effects or no effects at all. ...Read more

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What are the signs of triple-x syndrome?

What are the signs of triple-x syndrome?

Triple X: Tall stature, small head, vertical skin folds that may cover the inner corners of the eyes, delayed development of certain motor skills/speech/language, learning disabilities such as dyslexias, weak muscle tone. ...Read more

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How to deal with fragil x syndrome?

How to deal with fragil x syndrome?

Find experts in your: area by using the nfxf contact form at www.fragilex.org/foundation/contact/. A local Developmental/Behavioral Pediatrician & your state's Early Interventon Program if the child is < 3 years old or your public school district if he's 3 or older can evaluate him/her for ASD, ADHD + cognitive, adaptive, motor & behavioral issues & team with you to develop an individualized treatment plan. ...Read more

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What is the life expectancy with triple x syndrome?

What is the life expectancy with triple x syndrome?

Normal: Life expectancy should be normal. There are no effects that affect heart, or other major systems that would reduce life expectancy. ...Read more

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What family lifestyle changes would need to be made for triple X syndrome?

What family lifestyle changes would need to be made for triple X syndrome?

Depends on symptoms: Trisomy X syndrome can range from mild to severe, the life style changes would depend upon its severity. Pl see attached link forother details about the condition from the Mayo clinic. Good luck! ...Read more

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What is fragile x syndrome?

What is fragile x syndrome?

Defective chromosome: Each person has 23 pair of chromosomes. Males have xy and females xx. Some persons have a defective x with a portion that is missing. In females the other x compensates and they have no clinical problems. In males the defective x can result in retardation and/or autism. Some with defect can be normal but transfer problems to their sons. ...Read more

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What causes fragile x syndrome?

Chromosome defect: Patients with fragile x have a defective x chromosome. There are several variants, and not all cells may be affected. It is full disease only in males, but females can be carriers. It is a genetic disorder, but it often just occurs without warning. Affected boys can vary from normal to severe retardation and autism. There is no cure. ...Read more

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What causes of fragile x syndrome?

What causes of fragile x syndrome?

Gene mutation: Fragile x syndrome is due to a mutation within the fmr1 gene on x chromosome. Part of the gene gets repeated too many times. It is the most common genetic cause of intellectual disability. Please see: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0002633/ and http://www.Fragilex.Org/ for more information. ...Read more

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How prevalent is fragile x syndrome?

How prevalent is fragile x syndrome?

See below: Fragile x syndrome is the most frequent form of inherited intellectual disability. The prevalence in men runs from 1 in 4, 000 to 1 in 6.000. The prevalence in women is estimated at 1 in 10.000. ...Read more

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Fragile x syndrome, is it preventable, how?

Not preventable: while there is no way to prevent fragile X disorder, treatment with folic acid, a vitamin can be helpful with the behaviours if necessary. Behavioral therapy, applied behavioral analysis, A variety of medications are available for symptoms. You should consult a specialist working with children with Fragile X. ...Read more

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What is a fragile x syndrome?

Genetic problem: Fragile x syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females. http://ghr.nlm.nih.gov/condition/fragile-x-syndrome. ...Read more

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Whats the cause of fragile x syndrome?

Whats the cause of fragile x syndrome?

Genetic: Fragile x is caused by just one defective gene. This gene also known as fmr1, shuts it self down and fails to produce a protein. The incidence is 1 in 4000 males and 1 in 6-8000 females have it is the most common cause of inherited mental disability-. ...Read more

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Fragile x syndrome my baby, what to do?

Fragile x syndrome my baby, what to do?

Developmental help: Fragile X syndrome can predispose your baby to developmental and learning issues. It is important to have your baby evaluated by Early Intervention, a program to support infants with delays. Call your doctor to get this information. ...Read more

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How common is fragile x syndrome in us?

How common is fragile x syndrome in us?

Depends on your dfn: Significant impairment (iq<70) in FAS is felt to represent 1/3600 of the population, mostly male. A lesser form of involvement with lesser alterations in this gene (add, behavior issues) may affect 1/130-250 female & 1/250-800 males. See: www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc2888470/?Tool=pmcentrez. ...Read more

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Can you tell me about fragile X syndrome?

Can you tell me about fragile X syndrome?

Male dominated: The fragile x is named for a non staining region on the long arm of an x containing useless genetic material that results in mental impairment & physical changes(if you only have 1 x:males).The females usually show few if any features due to protection by a normal x, but not always & have a 50% chance of passing the fragile x to any offspring. This is a male dominated form of mental impairment. ...Read more

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What age does fragile x syndrome show up?

Birth: You can be suspicious at birth. Here is some information: http://www.fragilex.org/fragile-x-associated-disorders/fragile-x-syndrome/ ...Read more