Doctor insights on:
Triple Negative Breast Cancer Treatment
Need more info...: All else being equal, women with triple negative breast cancer have a worse prognosis than those who are receptor-positive; however, prognosis is highly correlated with the size of the cancer and the presence of cancer within the axillary lymph nodes. Furthermore, some women are more responsive to chemo than others, which will affect prognosis. ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Depends: Survival rates depend on multiple factors; age, response to treatment, stage of disease, your overall health. This is a conversation best had with your medical oncologist. ...Read more
O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.
32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy. What is survival rate?
Need Clarification!: Are you sure your breast cancer was triple positive(or was it triple Negative)??? TCH is commonly used chemotherapy for triple negative, so please double check and let us know. Then we can give you survival figures. In general, small tumors(Stage 1 and stage 2) have very good survival rate and high cure rates. ...Read more
Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done
Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read moreSee 1 more doctor answer
My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?
No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more
Herceptin (trastuzumab): The local treatment option (breast conservation versus mastectomy) are the same. The diff comes with systemic therapy. Her2+ cancers are more aggressive but this is counteracted by the biological (antibody) herceptin (trastuzumab). This is generally given with chemo. Since this is the case, it may often given before surgery (neoadj) to gain additional prognostic info and shrink the primary. ...Read moreSee 1 more doctor answer
It depends.: Tamoxifen is used to treat hormone-sensitive breast cancer. This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective. ...Read moreSee 2 more doctor answers
Chemotherapy: Triple negative implies the absence of estrogen and Progesterone receptors, as well as the absence of overexpression of the her-2 gene. Because of this, endocrine manipulation (tamoxifen, arimidex, etc. Doesn't work, nor does herceptin (trastuzumab). In addition to surgery (and sometimes radiotherapy), most triple negative patients receive combination chemotherapy. ...Read moreSee 5 more doctor answers
What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?
Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read moreSee 1 more doctor answer
Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?
Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read moreSee 1 more doctor answer
What are statistical odds for cancer returning in a 63 yr old woman 20 yrs after treatment for stage 1 breast cancer (lumpectomy, chemo, & radiation)?
Low, but not zero.: First of all, congratulations on being a 20-yr survivor! it is impossible to give you a number or even a range without knowing more specifics about your cancer, however, the fact that it hasn't returned in 20 years certainly puts you in favorable statistical category. I suggest that you meet with your medical oncologist to discuss this, as well as any measures you can take to prevent a recurrence. ...Read moreSee 1 more doctor answer
Radiation&breastCA: Every pt has the choice of mastectomy or breast conserving treatment. Some time after mastectomy radiation is added if we are worried the ca might have a high risk of coming back. Breast conserving tx is a minimal surgery followed by radiation. This allows the pt to keep their breast and hasa the same recurrence rate as a mastectomy. ...Read moreSee 1 more doctor answer
DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?
It depends: There are several chemotherapy options for stage 2a breast cancer. Characteristics of the patient and the cancer are required to make a decision on the type of chemotherapy (and whether chemotherapy is even necessary). Chemotherapy would be anywhere from about 8 weeks to a year (herceptin-or trastuzumab treatment, if recommended, requires a year of treatment). ...Read moreSee 1 more doctor answer
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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