Doctor insights on:
Triple Negative Breast Cancer Survival
Depends: Survival rates depend on multiple factors; age, response to treatment, stage of disease, your overall health. This is a conversation best had with your medical oncologist. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy. What is survival rate?
Need Clarification!: Are you sure your breast cancer was triple positive(or was it triple Negative)??? TCH is commonly used chemotherapy for triple negative, so please double check and let us know. Then we can give you survival figures. In general, small tumors(Stage 1 and stage 2) have very good survival rate and high cure rates. ...Read more
My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?
No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more
Need more info...: All else being equal, women with triple negative breast cancer have a worse prognosis than those who are receptor-positive; however, prognosis is highly correlated with the size of the cancer and the presence of cancer within the axillary lymph nodes. Furthermore, some women are more responsive to chemo than others, which will affect prognosis. ...Read moreSee 2 more doctor answers
Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done
Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read moreSee 1 more doctor answer
Very high!: The five year survival rate for all breast cancer is over 90%. Her2+ cancers used to have the worst prognosis, but Herceptin (trastuzumab) changed that. Now they have a very good prognosis if they are caught at an early stage (stage 1 or 2). The stage really determines the prognosis, so without that information i can't give you a number. But I am happy for my patients with a her2+ cancer-- many treatments! ...Read more
D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read moreSee 2 more doctor answers
O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.
It depends on many f: Most women with localized breast cancer do very well and there is high cure rate. Overall 75%-80% of breast cancers are curable. But you need to know what stage of cancer it is? You should also know what subtype(there are 3 different types) of breast cancer it is. Further there is the matter of what type of adjuvant therapy(post surgery treatment) was used. I'am sure your oncologist can answeryr. ...Read moreSee 1 more doctor answer
Yes: Breast cancers can be highly variable from one person to the next. Cell types and dna evaluations can be performed now that can help direct the best treatments for each person. Her-2 breast cancers may be best treated with specialized chemotherapy agent heceptin. ...Read moreSee 1 more doctor answer
My mom has 3rd breast cancer recurrence but is brca1/2 negative. Am I high risk for breast cancer?
Yes you are: Breast cancer does have some hereditary tendency. So sisters and daughters of a breat cancer patients have a small increase in their risk for developing breast cancer. yet >90% of the time there is no relationship to such an occurrence. So you need to be vigilant but not worry much about it. Just learn about breast self examination and do annual mammograms beginning at age 40 yr. ...Read moreSee 1 more doctor answer
Depending how used: CEA first identified in 1965 by Phil Gold and Samuel O. Freedman in human colon cancer extracts. Thought to be valuable for dx colorectal Ca but the glycoprotein is also expressed in inflamed tissue so that smoking and enema can cause rise. Best used for monitoring so that if present in primary and rises it represents treatment failure and if diminishes during treatment it represents a response. ...Read moreSee 5 more doctor answers
What are statistical odds for cancer returning in a 63 yr old woman 20 yrs after treatment for stage 1 breast cancer (lumpectomy, chemo, & radiation)?
Low, but not zero.: First of all, congratulations on being a 20-yr survivor! it is impossible to give you a number or even a range without knowing more specifics about your cancer, however, the fact that it hasn't returned in 20 years certainly puts you in favorable statistical category. I suggest that you meet with your medical oncologist to discuss this, as well as any measures you can take to prevent a recurrence. ...Read moreSee 1 more doctor answer
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?
It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read moreSee 3 more doctor answers
Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read moreSee 1 more doctor answer
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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