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Doctor insights on: Triple Marker Screening Test

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When should I repeat my triple marker test?

Need more info: The triple marker test is used to screen for chromosomal problems. Usually if it is abnormal further testing is done but the actual triple marker test is not repeated. ...Read more

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Dr. Chad Levitt
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Screening (Definition)

Examples are: colonoscopy for colon polyp or cancer; mammograms for breast lesions or cancer; psa a blood test that could indicate enlargement of cancerous prostate tissue; blood sugar or hemoglobin a!c for diabetes. Many think that scanning the whole body will pick up a cancer--in all likelihood, it will not. There also is no good blood test, yet, ...Read more


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Triple marker test on 15.6 week of preg. shows AFP 29.04ng/ml 0.67MoM, uE3 .98ng/ml 1.17MoM, hCG 48.10iu/ml 1.26MoM, Down;s risk 1:374, shud i worry?

Sounds normal : If your risk was 1:374 that sounds like a normal result. You can contact the ordering physician and seek clarification if you are in doubt but it sounds like your testing was normal ...Read more

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Does low hemoglobin and anemia cause low estriol and low AFP in triple marker test ?

Does low hemoglobin and anemia cause low estriol and   low AFP in triple marker test

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Low estriol /anemia: It should not. Need to see maternal fetal medicine specialist and have targeted ultrasound. ...Read more

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My wife has elevated ca 19-19 marker reading during routine health screening blood test. What do we do next to confirm if there is cancer or otherwise?

Is it CA19.9?: We usually do not recommend any tumor markers in routine blood test because they are neither sensitive nor specific. CA19-9 is frequently elevated in pancreatic cancer, cholangiocarcinoma, bile duct cancers, and etc. It can also be elevated in some benign conditions such as cholangitis or gallstones. Depending on its level, a CT scan and see GI doctor will be helpful. Did she have any symptoms? ...Read more

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Already had harmony test, afp, first trimester screening and they were all very low what might a dr suggest if soft markers are found on anatomy scan?

Already had harmony test, afp, first trimester screening and they were all very low what might a dr suggest if soft markers are found on anatomy scan?

Reassurance!: If all that's found is a soft marker, and your screening and cell free dna results are normal, the most likely answer is that the soft marker is a normal variant. However if there is a finding consistent with a birth defect, that might merit further investigation, such as diagnostic testing within amniocentesis. ...Read more

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At what level triple marker is considered dangerous?

More info needed: Could you repost your question with more information? I am not sure to what you're referring. ...Read more

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Cauc, 30 & 1st preg. Negative triple and NT test on 1st screen. 1/6123 risk for DS. 20 week screen showed fetal nasal bone at 4.6mm. High risk for DS?

Cauc, 30 & 1st preg. Negative triple and NT test on 1st screen. 1/6123 risk for DS. 20 week screen showed fetal nasal bone at 4.6mm. High risk for DS?

Fairly unlikely: Fetal nasal bone length is not a commonly assessed marker at 20wks gestation, instead we care more at 11-13wks. As fetuses grow, epigenetics and the environment have more of an effect on growth so a small nasal bone at this gestational age is not necessarily predictive in the setting of other reassuring testing. A noninvasive blood test may help to provide more reassurance. ...Read more

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Marker (Definition)

A "marker" is a protein or enzyme that can represent a disease process. Some markers are specific for a particular disease, while ...Read more