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Doctor insights on: Triple Marker Blood Test

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With so many false positives and negatives, does the quad marker blood test any real value, beyond random chance ?

With so many false positives and negatives, does the quad marker blood test any real value, beyond random chance ?

Efficiency: It guides the search for down's and grave neural tube defects in women who might want to end such pregnancies; it will miss some, but the alternative is much more problematic testing for all pregnant women. You are playing the odds but unlike in las vegas, "the house" is trying to give the most favorable odds to the patient. But getting a false-positive is most upsetting & we can all relate. ...Read more

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Marker (Definition)

A "marker" is a protein or enzyme that can represent a disease process. Some markers are specific for a particular disease, while ...Read more


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My husband has had two blood test taken, both indicated his kidney markers are significantly elevated. What does this mean?

My husband has had two blood test taken, both indicated his kidney markers
are significantly elevated.
What does this mean?

More work-up needed: Any medical test needs interpretation together with a patient's history, examination and imaging. Abnormal blood tests for kidney function suggest a need for further explanation of why. Reasons may include problems before blood flow gets to the kidneys (like narrowed arteries), problems with the kidneys (kidney disease) or after the kidneys (like prostate enlargement). Don't panic, get evaluated. ...Read more

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Please explain what does p s a mean in a tumor marker blood test?

Please explain what does p s a mean in a tumor marker blood test?

Test for prostate ca: PSA is a blood tumor marker for prostate cancer but can be elevated in prostatitis, a benign inflammation of the prostate. It is especially helpful in screening men for early prostate cancer and In following the effectiveness of therapy. There is controversy in recent years in whether elderly males should be screened or not as prostate cancer can be slowly progressive without treatment . ...Read more

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I was wondering what does "p s a" mean in a tumor marker blood test?

I was wondering what does "p s a" mean in a tumor marker blood test?

PSA: Psa is an acronym for prostate specific antigen. A very high level of this marker in the blood could be indicative of prostate cancer, however there has been much debate recently as to how good a screening test it is. Higher than normal psa levels can be caused by benign growths. ...Read more

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What is the blood test that could be a marker to detect early cirrhosis?

What is the blood test that could be a marker to detect early cirrhosis?

More than one/many.: Cirrhosis is a broad condition that covers so many causes that there are many blood tests that indicate it and the cause. In general cirrhosis, low red cell count, low albumin, and high prothrombin time, indicate the liver's inability to do its job due to cirrhosis. These can happen before cirrhosis and can mean worse prognosis. Hepatitis abs, anti-mitochondrial ab, etc. Point to the causes. ...Read more

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Rheumatoid - my blood test show a very high marker. How serious this can be and any prevention?

Rheumatoid - my blood test show a very high marker. How serious this can be and any prevention?

Depends: Depends on whether you have any arthritis or infection. Rheumatologist evaluation necessary to determine if it means anything. Prevention is not an issue. ...Read more

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Can a blood test for 'lymphocyte surface markers' rule out lymphoma? Or is biopsy truly the only way?

Biopsy is best: If lymphoma cells are circulating in the bloodstream, they might be able to be identified by flow cytometry (which is a test for lymphocyte surface markers). However, the most reliable method would be to perform a biopsy of any enlarged lymph node. Plus, if there is lymphoma, there are important aspects of a biopsy diagnosis that cannot be derived using a blood test. ...Read more

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My wife has elevated ca 19-19 marker reading during routine health screening blood test. What do we do next to confirm if there is cancer or otherwise?

Is it CA19.9?: We usually do not recommend any tumor markers in routine blood test because they are neither sensitive nor specific. CA19-9 is frequently elevated in pancreatic cancer, cholangiocarcinoma, bile duct cancers, and etc. It can also be elevated in some benign conditions such as cholangitis or gallstones. Depending on its level, a CT scan and see GI doctor will be helpful. Did she have any symptoms? ...Read more

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