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Obligate parasite.: Treponema pallidum is the pathogen that causes syphilis. It is very difficult to grow in culture because unlike most bacteria, it cannot survive outside of mammalian cells (i.e. On a petri dish), thus it is considered an obligate parasite. It has limited metabolic capacity, and cannot synthesize many biomolecules, which it requires from a living host. This has posed a hurdle for researchers. ...Read more
Depends: T.Pallidum, the germ cause of syphilis can pass from mother to child in any stage of pregnancy. The effect on the embryo or fetus ranges from death to major multiple-organ disease to a mild neonatal form that may be overlooked, but can cause long term defects. Ob's typically screen early & late in pregnancy to find & treat this condition as soon as possible. Newborns may have meningitis. ...Read more
What could cause chronic joint pain (most joints) in otherwise healthy 25 yo male? Rf, ana, treponema pallidum, sedimentation rate all normal.
Inflammation: Inflammation has many possible causes. There is the possibility of seronegative RA (ra test is negative); given that all of your tests are negative focus on nutritional causes. Stop all acid intake especially sodas; increase antioxidant intake and herbal antiinflammatories and a new product on the market that has been shown to reduce oxidative stress to near nothing. Www. Medacpc. Com for more. ...Read moreSee 1 more doctor answer
How could syphilis test be negative and anticardiolipin autoantibody be positive? Do some syphilis tests only look for antibodies to t. Pallidum?
Does the "t. Pallium screening cascade" only test for autoantibodies against t. Pallidum...Or does it also test for anticardiolipin autoantibodies?
T pallidum only: It does not test for anticardiolipin antibodies. ...Read more
Few things: Calcifications in globus pallidus portion of basal ganglia are usually detected by ct of brain. In older individuals (1% population) calcifications are part of aging process. Younger than 40y are abnormal and should have workup by physician. Calcifications can be idiopathic (farr diseae) heavy metals, cong. Infections, metabolic (renal failure, 2ndary hyperparathyroidism, etc.). ...Read more
47 yo fem. W/fatigue, ha & memory loss. Mri 9/9 & 11/12/13 abnormal t2 hyperintensity involving the globus pallidus bilaterally. Neuro says normal?
Let's evaluate: Your fatigue, memory loss, and headaches are not "normal", and can be caused by thyroid, b-vitamin deficiencies, psychological issues, migraine, infection, etc. The bilateral t-2 lesions may be nonspecific, but should not be glibly dismissed, at this point. A cause for your complaints should be sought. Consider a second opinion. ...Read more