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Doctor insights on: Treatments For Pleomorphic Adenoma

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Pleomorphic (Definition)

We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more


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Hi..i need help..will you please tell me or explain to me the pathophysiology of pleomorphic adenoma? Thanks

Hi..i need help..will you please tell me or explain to me the pathophysiology of pleomorphic adenoma? Thanks

Little to it: The anatomic pathology of pleomorphic adenoma is amazingly complex, and we are learning a bit about its molecular biology. The lesions are benign but locally destructive, especially endangering the facial nerve if in the parotid. Wide excision is required as the lesion sends out projections. Around 1% is the site of origin for a real cancer. ...Read more

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I ve 1.8cm *1.3cm pleomorphic adenoma on superficial lobe of patotid gland.scared to do surgery.possible complications of surgery?postoperative care?

I ve 1.8cm *1.3cm pleomorphic adenoma on superficial lobe of patotid gland.scared to do surgery.possible complications of surgery?postoperative care?

Surgery mandatory: The benign tumor will just get bigger and bigger and the risks of nerve damage will be higher. Procedure safe with an experienced surgeon. Recommend Jeffrey Spiro, M.D., Professor, Department of Surgery. U Conn Medical Center, Framingham CT 860-679-2804 ...Read more

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If you had a benign pleomorphic adenoma in a minor salivary gland for approx 5 years would you have it surgically removed?

Yes: These lesions can grow and can undergo malignant transformation. I almost always rec excision. Find an ENT doctor who does frequent parotidectomies with facial nerve dissections. ...Read more

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Could my son get cancer if he was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek?

Rarely: Pleiomorphic adenomas are benign tumors of saliva glands. It is unusual for them to be in the neck itself, but they can arise "rests" of salivary tissue in the neck. They tend not to spread to other parts of the body but can grow back in the areas where they arose in about 20% of patients who had surgery. Rarely they can turn cancerous and spread to other organs. Best wishes. ...Read more

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My son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Could this become cancer?

Pleomorphic adenomas: These salivary gland tumors are usually benign. If the tumor is of the mixed type it could become cancerous ...Read more

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What do you suggest if my son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. can this turn into cancer?

What do you suggest if my son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. can this turn into cancer?

Early ENTinvolvement: Close follow-up with the ENT, surgical resection is required. Yes, these have a high rate of malignant transformation. ...Read more

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My mum was diagnosed with pleomorphic parotid adenoma and she has a heart condition. Is an operation really necessary? My mum is 79

My mum was diagnosed with pleomorphic parotid adenoma and she has a heart condition. Is an operation really necessary? My mum is 79

An operation: is generally necessary. Ask your doctor whether or not her medical risks outweigh benefits of surgery, because a lot depends on the severity of her heart condition. ...Read more

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Dr. Murthy Andavolu
1,344 doctors shared insights

Adenoma (Definition)

Adenoma is a term for a harmless tumor of gland tissue, including glands found in the intestines, kidney, ...Read more