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Treatments For Ocular Myasthenia Gravis
Muscle weakness: Other reasons for decreased use of muscles. This could be muscle diseases and neurological diseases. The usual clue is the occular involvement. This is where testing is done. Testing is to replace the loss of acetylcholine function like the tensilon test and other drugs that block the beakdown of acetylcholine by cholinesterase andtemporarily increases the level of acetylcholine and reverses it. ...Read more
How often does ocular myasthenia gravis progress to general? I was recently diagnosed with ocular myasthenia gravis. My doctor says it will most likely spread to the rest of my body, but that it's possible it won't. What are the odds i'll be lucky enough
Ocular : Ocular myasthenia gravis affects the muscles of the eyes. It often begins with drooping eyelids or double vision, usually less in the morning than at night. According to the neurological literature, over 50% of people with ocular involvement develop generalized myasthenia in 2 years. Some studies have been done looking at treatment with Prednisone to reduce that incidence. Removal of the thymus gland is sometimes done. There are treatments available that modify the immune reaction such as plasmapheresis, intravenous immune globulins and some anti-immune drugs. The first drug used is called an anti-cholinesterase. Acetylcholine is the chemical released by nerve endings that activates muscle cells. In myasthenia gravis the problem is loss of receptor sites or "docking stations" the ach has to attach to to activate. Anticholinesterases inactivate the cholinesterase that would break down the ach before it finds a place to sit. It's a little like an odd game of musical chairs. These docking stations and acetyl choline are present on all muscle cells both in the eyes and in the limbs. Careful follow-up will keep the process under control. ...Read more
52 year old female having ocular myasthenia gravis for past 2 years& hashimotos thyroiditis sgpt 323 sgot 523 ALP 330 totl bilrubn 2.6 &dirct 1.2?
Elevated liver tests: Along with myastenia and Hashimotos it looks like there is some type liver process invovled. It could be a primary liver probem or related to medications. You need to try to tie these all together. A rheumatologist and a gastroenterologist can help you with these. ...Read more
Different uses: Acetylcholinesterase inhibitors are the first line of treatment due to their safety and ease of use. Pyridostigmine (Mestinon) is the usual choice. Neostigmine is available but not commonly used. Edrophonium is an acetylcholinesterase inhibitor but does not come in an oral form. It is mainly used as a diagnostic agent for MG. ...Read more
Are there any new treatments for myasthenia gravis rather than the traditional cortisone and mestinon (pyridostigmine) or thymectomy?
Not really: Those are the tested ones.Get a more detailed answer ›
Multiple: About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties. Chronic and/or longterm medications may aid but can have significant adverse impact on life and/or health. In appropriate candidates, thoracic surgery to remove thymus (thymectomy) can possibly cure: http://goo.Gl/3xxmd. ...Read moreSee 1 more doctor answer
Not sure: This doesn't sound like "conventional" therapy, but if it doesn't hurt/cost much/is harmful, then why not try? More conventional wisdom on mg can be found here: http://www.Ninds.Nih.Gov/disorders/myasthenia_gravis/detail_myasthenia_gravis.Htm. ...Read more
No dose change, but WHY some days when take my Vicodin I'm FINE then other times feel weak,tired,SOB? I do have myasthenia gravis. Any ideas?
INTERPRETATION: Vicodin is an opioid analgesic and has NO beneficial effect on the neuromuscular junctional issue in myasthenia. I am unaware if you are taking Mestinon (pyridostigmine) or steroids or other immunological agents, but if you are fluctuating, you do need specific meds for your weakness, in spite of prior thymectomy. Suggest a visit to a neurologist who focuses in neuromuscular areas. ...Read more
Should i get my thymus removed to treat my myasthenia gravis? I don’t have a tumor in it, but my doctor says it’s a little enlarged and he wants to take it out. I’ve read that if you take out your thymus you get another disease because you lose the hormon
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