Doctor insights on:
Treatments For Aortic Sclerosis
Need chronically: Some advice, there are pills available, but where you live, might be tough to get. Nonetheless, do not miss your injections, and add Vitamin D-3 about 5000-10000 units per day. We do not have a clear idea when to stop the MS meds, and in those older patients who I have stopped, a few have had relapses. Stay tuned, drugs to be used differently are on the horizon. (even Lemtrada) ...Read more
D-penicillamine might work, and there a number of studies suggesting this, but no long term double blind studies exist.
A recent report suugest that a drug CellCept (mycophenolate mofetil) might be of value, and there are those that use mtx or tetracyclines. The major advances are ability to control BP and treat pulmonary hypertension. We can deal with esophgeal spasm and reflux. Nothing great at present for underlying dx. ...Read more
Not curable: The disease is managed by surgery for the tumors as applicable, and medications. No two cases are alike. Ask about sirolimus if this question applies to a family member. Patients who wish to become parents will do well to learn how to prevent transmission of the illness to their children. Best wishes. ...Read moreSee 1 more doctor answer
Managed, not cured: Ts is a lifelong process whose treatment begins with recognition, education and monitoring through life. It can be quite mild with no long term effects, or be devastating. Related seizures & emergence of soft tissue "tubers" in the brain & major organs can create problems. Periodic ct scans & ultrasounds to monitor the organs are common. Coordinated efforts of local & specialty drs is a must. ...Read moreSee 1 more doctor answer
Support/encourage: Aortic sclerosis is quite common as people get older, 25-30% in those>65 yrs of age. It is the calcification and thickening of the aortic valves without flow obstruction, but it a marker for athersclerosis/heart disease. Encourage him to take good control blood pressure, cholesterol, diabetes etc--take meds! . And don't smoke. Regular exercise, keep ideal body wt. Consult doc regularly. Good luck. ...Read more
For someone who is 40 years old, what are the long term detrimental impacts of interferon treatment for multiple sclerosis?
Interferon: The real question you should be asking is "what are the detrimental effects of not taking interferon for treatment of ms". Ms can be a deadly disease and medications are chosen and recommended by physicians after a careful consideration of risks versus benefits. Ask the prescribing physicians for information that will help you look at both sides of this issue. ...Read moreSee 2 more doctor answers
Getting exciting: Original meds included self-injectables, such as betaseron, avonex, compaxone, and rebith. Later, tysabri (natalizumab) infusions, and 2 oral meds, Gilenya and aubagio. We now know that vitamin d supplements provide added benefit. No one med fits all, but most effective drugs currently are Gilenya and tysabri (natalizumab), and these work best of the current crop. ...Read more
No unique answer: MS has many forms, many phases, individuals respond in all sorts of different and at times unpredictable ways so there is no BEST drug to tell you about. Latest research suggests the use of interferons and immunomodulating drugs is what best manages this disease. Unfortunately, there are plenty of problems with that approach but your doctor will discuss all the options with you. ...Read more
First line therapies include:
-interferon beta-1a (avonex) im once a week.
-interferon beta-1a (rebif) sc three times a week.
-interferon beta-1b (betaseron, extavia) sc every other day.
-glatiramer acetate sc (copaxone) sc daily.
Second line therapies include:
-mitoxantrone (novantrone) IV q3months.
-natalizumab (tysabri) IV q4weeks.
-fingolimod (gilenya) PO daily. ...Read more
Not really: It might be a fond hope to find such, but, if one has ms, treatment with disease modifying items is very important, and, in most cases, the most potent drugs are best. You can improve outcomes with supplements of vitamin d-3, perhaps b complex, low fat diet, exercise, and stress management, but these approaches do not replace the medicines. ...Read more
All are permanent: All treatments for MS are not curative, in order to stop or slow down the progression of the disease, you have to take them indefnitely. I hope this answers your question, not sure what you mean by permanent. If you mean that the treatments "permanently" stop progression, only possibly if you keep using them. I like tysabri (natalizumab) despite the side effects. I see MS lesions literally disappear. ...Read moreSee 1 more doctor answer
Many: We have 12 drugs approved to treat MS, and more on the way. The newest are Tecfidera, Plegridy, and the most potent drug of all, Lemtrada. Coming are newer mono-clonal antibodies, a drug to restore myelin damage, and even some treatment for the progressive forms. ...Read more
Complex: We do not know the exact cause of this autoimmune disease that attacks brain and spinal cord, but do find that both heredity and environment play roles in susceptibility. We are gaining new medicines which are far more potent (altho maybe risky), which can control the disease far better. The most potent available include tysabri (natalizumab) and gilenya. No cure yet, but stay tuned, it is close. ...Read more
My opinion: For what it's worth, each ms patient is unique and not all meds fit each person. Yet, you want a potent effective medicine, and nowadays we have lots of choices. Must consider risks and side effects. Most effective meds in descending order would be tysabri, (natalizumab) gilenya, tecfidera, rebif, betaseron, aubagio, copaxone, and lastly avonex. No perfect med exists commercially.. ...Read more
Autoimmune: Ms is a disease where the immune system attacks the coverings of nerves in the brain and spinal cord. Susceptibility due to heredity and environment seem to affect who gets afflicted. The prognosis is improving dramatically these days due to new medicines. Therapies include tysabri, (natalizumab) gilenya, copaxone, betaseron, rebith, extavia, etc. ...Read more