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Treatment Osteomyelitis Patient Disease Caused Salmonella
Which treatment for osteomyelitis of a patient with sickle cell disease and the osteomyelitis is caused by salmonella?
Osteomyelitis is an infection of the bone. Osteo is derived from the greek osteon..Inflammation or infection. A broad range of organisms can cause infection from bacteria, to viruses (less common), to fungi (mycotic). Acute and chronic infections exist. Long term IV treatment with antibiotics (or antifungals or other agents) are needed. In my experience no less than 8 weeks ...Read more
Salmonella osteo: This depends upon whether this is acute vs. Chronic osteomyelitis. In the chronic form you may need input from an orthopedical surgeon for debridement of devitalized bone combined with a long-term antibiotic preferrably given iv, although if sensitive to a fluorinated quinolone like Cipro (ciprofloxacin) this may be effective orally over at least a 4 wk course. ...Read moreSee 1 more doctor answer
Why is there an increased risk of developing osteomyelitis in sickle cell anaemia patients having salmonella infection only? (pathogenesis)
Sickle cell disease: Although salmonella frequently cause osteomyelitis in sickle cell dz patients, it isn't the most common cause - the most common cause remains staphylococcus. Sickle cell dz predisposes to infections including osteomyelitis due to: hyposplenism & infarcted bone (due to microvascular occlusion). Salmonella is thought to spread from intestine secondary to microinfarction of bowel caused by sickling. ...Read moreSee 2 more doctor answers
4yr w/ staph/salmonella osteomylitis tx: 2wk IV ab & 4wk oral amox- postlab work- mpv 8.1, eoso .43 2mth p pinprick petechiae on hands ++uri's- worry?
Question unclear: If you have a 4 year old with these conditions you should have them seen by a pediatric infectious diseases expert. If this is in an adult it is very unusual to see both staph and salmonella producing osteomyelitis in the same patient. If you are being treated and are having petechiae you need to see a doctor immediately and consider having an echocardiogram and ruling out allergy. ...Read more
Oral hydration: Salmonella typhi (typhoid fever) is transmitted by drinking or eating contaminated water or food. High fever, headache, abdominal pain and rash are possible symptoms. Oral hydration is the mainstay of treatment, although IV hydration may be needed in serious cases; oral antibiotics may also be recommended. Anti-diarrheal meds are usually not recommended. ...Read moreSee 1 more doctor answer
Supportive care: Gastroenteritis, the most common manifestation of salmonella infection in us, generally requires a supportive care, i.e., maintaining good fluid balance. Exceptions include young infants and individuals with sickle cell disease who may require antibiotics treatment. ...Read moreSee 1 more doctor answer
See below: Most cases of osteomyelitis in adults need surgery and antibiotics. Because it takes 6 weeks for debrided bone to be covered by soft tissue, and experience that shorter courses of antibiotics have a higher relapse rate, 4-6 weeks of IV antibiotics is recommended. In models of osteomyelitis 4 weeks of antibiotics was more effective in sterilizing bone than 2 weeks. ...Read moreSee 1 more doctor answer
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