Doctor insights on:
Treatment Of Prothrombin Factor 2 Gene Mutation During Pregnancy
My partner has ulcerative colitis and prothrombin gene mutation, is it possible these conditions are linked?
No: They are likely unrelated.Get a more detailed answer ›
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Throbophilia: A gain of function mutation of the prothrombin gene results in higher levels of prothrombin, a clotting factor, and predisposes the person to forming clots in blood vessels. You may consult this site for more info: https://www.healthcare.uiowa.edu/labs/lentz/Information_For_Patients/PDF/Prothrombin%20Gene%20Mutation%20Brochure.pdf For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more
What is a prothrombin gene mutation? It is something worth worrying about whether you have it or not?
PGM: Prothrombin gene mutation is an inherited coagulopathy. This means that if you have this gene mutation, you can be at increased risk of forming clots in certain veins in your body. These clots can be dangerous and even lead to death. We do not routinely check for this mutation but do order this test if a young patient develops a deep blood clot. ...Read more
I have prothrombin gene mutation g20210a, i'm pretty sure i follow under a vitamin defect. Is their anything i can do?
Prothrombin G20210A: Prothrombin is the precursor of thrombin in the coagulation pathway; it is synthesized in the liver, much as other vitamin k – dependent proteins are.The prothrombin gene is found at 11p11-q12) on chromosome 11. mutation at position 20210 of the gene results in thrombophilia.This coagulopathy is more likely to cause venous thrombosis rather than arterial disease. Is not related to a vitamin deficit. Coumadin (warfarin) is the treatment of choice. You seem to be in the hands of a good hematologist. I am truly sorry to hear about your stroke.I can understand your concerns as i also suffer from three clotting factor disorders and am on coumadin (warfarin). Best wishes for a happy and healthy new year. ...Read more
Is cancer my next battle? After stroke, dvt, p.E. I have prothrombin gene mutation g20210a. I'm currently cancer free but what are my odds?
Why do you ask?: You have given me no reason to believe that you have cancer. The cancer that's most famous for causing thrombi -- common pancreatic cancer -- would be very rare at you age of 29. I suspect you have some additional unknown cause of hypercoagulable blood and need to stay under the care of a good hematologist. If you do develop a mass or new symptoms, get seen, but don't let fear ruin your life now. ...Read more
I have prothrombin gene mutation g20210a, i've had a p.E & DVT & stroke in the past 2 years. Cancer runs in the family, but i'm currently cancer free?
What's your question: We'd all like to help, but you haven't made clear what you're asking. I'm glad you're being treated after your thrombotic events. If you can let us know exactly what we can do for you, please resend your question. ...Read more
Pregnancy mutations: Conception is a function of two sets of chromosomes, 22 + X from an egg and 22 + X or Y from a sperm. The resultant combination goes through a "re-mixing"_ process that requires pairing the chromosomes with subsequent "detachment" If the detachment process is not a complete "pair", then gene mutations occur especially in women older than age 37. ...Read more
I asked about thanataphoric dysplasia & I understand it is a new gene mutation, but what is its risk of recurrence in following pregnancy?
Testing: If neither parent is affected by achondroplasia then this is most likely a de novo mutation in the FGFR3 gene. This means clinically that the risk of recurrence is not higher than the baseline risk for everyone (1/20,000). Mosaicism (carrying gene but not expressing) by testing the parents DNA through targeted molecular genetic testing. ...Read more
Does heterozygous for MTHFR gene mutation affect pregnancy?, and what about taking synthetic folic acid supplement?
Controversial...: Some studies have shown an association between the MTHFR gene mutation and recurrent miscarriages but this is controversial. Aside from this possibility, it doesn't cause problems with pregnancy. If you have this mutation, its a good idea to take folic acid, vitamin B-12 and Vitamen B-6. Aspirin is also sometimes recommended for women for who have had recurrent miscarriages. Best wishes! ...Read more
When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more
In genetics, a mutation is a change in the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to dna or to RNA genomes (typically caused by radiation or chemical mutagens), from errors in the process of replication, or from the insertion or deletion of segments of dna ...Read more