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Doctor insights on: Treatment Of Hurthle Cell Metaplasia Thyroid

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Metaplasia (Definition)

"metaplasia" refers to one tissue type undergoing a change to another, such as bronchial lining (which is usually a single layer of cells, "respiratory epithelium" becoming multi-layered and heavily keratinized, so-called squamous metaplasia. This is common in smokers. Other such changes can produce tissue such as ...Read more


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Thyroid fnac report-atypia of undetermined significance or follicular neoplasm. What it means? Treatment?

Thyroid fnac report-atypia of undetermined significance or follicular neoplasm. What it means? Treatment?

Thyroid FNA: Hi. A follicular neoplasm of undetermined significance means the cytology doesn't meet criteria for cancer or benign, thus the "undetermined significance". Historically, most of these turn out to be benign, but a significant subset are cancer. It appears they did not do gene testing. Next step would usually be surgical excision of the nodule, frozen section analysis, then total thyroidectomy if CA ...Read more

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Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?

Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder.  Is this lymphoma?

Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more

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What is "rare epithelioid giant cells" in fna of thyroid nodules?

What is "rare epithelioid giant cells" in fna of thyroid nodules?

Review with your MD: Usually, when one aspirates a thyroid cyst one may see "rare epithelioid giant cells". Most simple cysts of the thyroid are benign. However, fine needle aspirate of cystic papillary thyroid carcinoma may also show this feature and may lack diagnostic cells. So, additional information is needed to interpret the cytology report. ...Read more

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What is papillary thyroid carcinoma with tall cell variant?

More aggressive: This is a form of thyroid cancer that has a worse prognosis than the typical papillary cancer. It is not the worst form of thyroid cancer. This is also associated with a mutation in the cancer cells call b-raf. There are some new drugs that attack this kind of tumor in later stage. ...Read more

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Biospy of thyroid report "Macrofollicular thyroid parenchyma, suggestive of nodular hyperplasia" What does this means?

Biospy of thyroid report "Macrofollicular thyroid parenchyma, suggestive of nodular hyperplasia" What does this means?

Not cancer: It would be helpful to talk to the pathologist who rendered the diagnosis, however, from the information you provided, you do not have thyroid cancer. ...Read more

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Is squamos cell carcinoma of tonsils cureable?

Is squamos cell carcinoma of tonsils cureable?

Yes: It may be curable but you will need and extensive work up and close follow up with your otolaryngology surgeon (ent). Depending on the extent of cancer treatment may consist of any combination of surgery, radiation, and chemotherapy. Maintaining your nutrition and mental health during this time would be very important as well. ...Read more

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Fnac report of thyroid nodule-colloid, individual follicular cell n folliculr cell in cluster in haemorrhagic bckground. What it indicate?

Nothing: Reports states the nodule was benign which means not cancerous, hemorrhagic, there was some blood which was probably from the size of needle used so don't worry. ...Read more

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Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?

Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma.  What does this means.?

Needs treatment: Means you have cancer of oral cavity ( buccal mucosa ) from your description appear to be localised you will have good prognosis needs further work up for staging &care , by surgical excision for localized small area, or chemo radiation , discuss with your physicians and please do not delay . Good luck. ...Read more

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Whats the treatment for follicular adenoma thyroid nodules?

Whats the treatment for follicular adenoma thyroid nodules?

Watch them: Unless they are large, the treatment for adenomas of the thyroid is observation. They are removed when they are bug enough to cause symptoms. ...Read more

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Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Pap: you need to have your pap test repeated in 3 months to see if has reverted to normal, by in itself cells with dysplasia only means that you may have had a past infection or may have HPV ...Read more

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What is rare histiocytes and follicular cells in thyroid nodule?

What is rare histiocytes and follicular cells in thyroid nodule?

Incomplete informat: The presence of histiocytes (a type of inflammatory cell) & expected follicular cells in thyroid is not necessarily worrisome. But it depends on your symptoms, & what prompted the biopsy / FNA to begin with. Also, did you have a radioactive iodine exam? (Called "thyroid uptake & scan")? That tells you if the follicle is "functional" or not (making hormone). A hyperfunctional nodule is more worriso ...Read more

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What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

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What do these biopsy results of thyroid nodule mean ATYPIA OF UNDETERMINED SIGNIFICANCE OR FOLLICULAR LESION OF UNDETERMINED SIGNIFICANCE?

Re-FNA in 3-6 Months: Hi Jami, AUS/FLUS is a term that cytopathologists use for thyroid nodules that they basically are "unsure" about. Classic management for this diagnosis is to have a second repeat FNA in 3-6months. Nowadays though high tech molecular pathology tests can sometimes divide AUS/FLUS definitively into benign and malignant categories. Please setup a virtual consult with me for more information. ...Read more

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Solitary, solid nodule with intranodular flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Solitary, solid nodule with intranodular  flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Ask your doctor: The doctor who ordered your biopsy has responsibility to explain to you the meaning of the results. If the biopsy shows neoplastic cells, that usually means Cancer cells. But you should get this clarification from your doctor. ...Read more

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Causes & treatment of reactive follicular hyperplasia of lymph node?

Causes & treatment of reactive follicular hyperplasia of lymph node?

Often unexplained: Most young adults have at least one palpable lymph node in the neck, and if it's sampled, it usually shows follicular hyperplasia. We usually don't find the cause and assume it was just a though node fighting germs. If a cause is found, it's often hiv, rheumatoid arthritis, syphilis, toxoplasmosis, or common variable immunodeficiency. ...Read more

Dr. Daniel Saurborn
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Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more