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Doctor insights on: Treatment Of Hurthle Cell Metaplasia Thyroid

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Metaplasia (Definition)

"metaplasia" refers to one tissue type undergoing a change to another, such as bronchial lining (which is usually a single layer of cells, "respiratory epithelium" becoming multi-layered and heavily keratinized, so-called squamous metaplasia. This is common in smokers. Other such changes can produce tissue such as ...Read more


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I recently had a FNA of my thyroid nodule. The results showed "benign, hyperplastic nodule with extensive Hurthle cell metaplasia". Should I worry?

I recently had a FNA of my thyroid nodule. The results showed "benign, hyperplastic nodule with extensive Hurthle cell metaplasia".  Should I worry?

Needs surgery: see your doctor. You need a referral to a surgeon. Hurtle cell can be benign or malignant. It is impossible to tell whether it is benign or cancerous on a fine needle aspiration. You need surgery to remove that side of your thyroid in order to know100% if it is one or the other. ...Read more

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Is there a kind of hyper thyroidism that resolves without treatment ?

Is there a kind of hyper thyroidism that resolves without treatment ?

Yes: Dequervain's thyroiditis can make you hyperthyroid for a few days or weeks then self-cure. Another cause is eating beef into which the animal's thyroid was accidentaly placed by the butcher. ...Read more

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My fna of thyroid revealed groups of epithelial cells in macrofollicular patterns. Are these bad/pre-cancer cells? What should follow up treatment be?

Ask your doctor.: Epithelial cells in macrofollicular patterns are usually benign thyroid cells and are usually not associated with a premalignant or malignant process. This is good news. Ask the doctor who ordered the fna to help you interpret the report and to answer your questions. That person will be able to give you information in the context of your personal clinical setting. ...Read more

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What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

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Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Surgical biopsy: Hi. Going just on what you've told us, you probably need a surgical biopsy. A Hurthle cell neoplasm can be either benign or cancer, and the cytopathology often cannot make the distinction. Therefore, to exclude or confirm cancer will require a surgical biopsy. But I don't have the data. Your doc will tell you what's needed. Good luck! ...Read more

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What is the optimal TSH for a 61 year old female who 16 years ago operated thyroid gland due to hurthle cell ca. ? My TSH during all these 16 years (after the operation) was 0, 6 - 0, 4 . But two months ago I changed the original swiss medicine eltr

As : As you know, TSH (thyroid stimulating hormone) is secreted by your pituitary gland to stimulate the synthesis and release of thyroid hormones from your thyroid gland (which has been removed, in your case). Since TSH can also stimulate the growth of thyroid cancer cells, one goal of therapy for thyroid cancer patients is to suppress their TSH to the lowest possible level while keeping their triiodothyronine level (t3) within a normal range. (many physicians strive for a TSH less than 0.1 as long as the patient's T3 (liothyronine) doesn't climb higher than normal). This usually requires a levothyroxine dose between 2.2 and 2.8 mcg per kg of body weight (about 170 to 220 mcg for a 172 lb individual). I hope that helps! ...Read more

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32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

Thyroid nodules: Usually we worry about a solitary nodule in a male and it appears that you are in good hands and the biopsies are reassuring. For further reassurance we depend on a combination of an endocrinologist or thyroidologist and a surgeon skilled in thyroid surgery reviewing your findings and I would be quite comfortable with their advice and follow-up. ...Read more

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1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

Now benign: From your information it isa benign adenoma , hurthle cell are little larger pinkish cell , but have higher incidence of malignant transformation than follicular , to hurthle cell carcinoma , unlike follicular , it will spread to lung , bone etc, follow your doctor's advice. ...Read more

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Dr. Ronald Krauser
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Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more