Doctor insights on:
Treatment For Stage 3b Colon Cancer
Not good, but: Each person is unique. Discss this question w/ the doctors involved in treatment. It's not good, but there are certainly cases that will do better than others. All life ends. Stage 4 cancer is quite advanced and life expectancy is shortened significantly. Overall health can matter a lot for how long and how good. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
If have stage 3b colon cancer and refuse to do port treatment and will only do pills how does it affect your chances?
A central IV port is no big deal. Regardless of the stats, why toss out this option (a mainstay of Rx) even before giving it a try? Please remember this can be a really nasty disease and I'd like to see you fight it with all you've got. I would hate to have you regret tying one hand behind your back years from now.
I personally have been fighting cancer for 20 years and I like the challenge. ...Read more
What other treatment that folfox for 6 months do you reccomend for someone with a stage 3b colon cancer T4, n1c without lymph nodes involvement? Any o
Tough one: Well if it is n1, than lymph nodes are positive. If n0 that means lymph nodes are clear or negative. I think folfox 6 months is usually given for stage 3 (lymph node +) disease. Ilook at age, family history, grade of tumor, lvi, oncotype recurrence score if MMR +, perforation or not and if pt really high risk, than 2 years of Xeloda (capecitabine) as risk of relapse is high in first 2 yrs. It is not standard. ...Read more
Surgery+/-ChemoRx: The cornerstone of therapy is surgical resection of the part of the colon. The stage of the cancer is dependent upon the surgical findings (depth of cancer, lymph node evaluation), which will guide the decision regarding chemotherapy. Very rarely, radiation therapy will be recommended for more advanced colon cancers. ...Read more
Many: Colon cancer is so common that many medical trials have been performed which help doctors know better how to treat this disease. Depending upon the patient and stage of cancer, surgery, radiation, and various chemotherapies may be of benefit. You oncology team who know your specific situation can give more specific recommendations. ...Read more
Many options: Colon cancer is best treated in a multidisciplinary fashion according to location and stage at diagnosis. Most treatments are iv, but several oral agents are used as part of treatment regimens including Capecitabine (xeloda), and some targeted agents in trials. Treatment in early stages or selected patients with stage IV disease also involves surgery and may involve radiation. ...Read more
Depends: This depends on so many things, where it is, how invasive, what type of cancer, metastasis, patient health, etc. I do not mean to make light of it any way and I hope you are not dealing with it. While some may have successful treatments, it is very hard to say on any prognostic factors without a lot of detail in this specific circumstance. I know this does not clarify much, but hope it helps. ...Read more
Why do people become upset when I say if I get colon cancer im most likely going to refuse treatment?
Surgery and? Chemo: The first step is to remove the tumor and lymph nodes to see if tumor has spread to these. Since you know it is stage iii this must have already be done. We know in patients with the disease spread to nodes around the tumor, it is more likely to recurr. The addition of chemotx reduces this risk. Talk to an oncologist about the risks and benefits of the chemo. Most patients should recieve it. ...Read more
Surgery, chemo: Depending on the stage, an operation is usually necessary to remove the diseased portion of the colon along with its nearby lymph nodes. Then, depending on if the cancer has spread to those lymph nodes impacts whether you will also need chemotherapy. If the cancer has already spread beyond the colon, sometimes you start with chemo. ...Read more
Yes: While chemo like FOLFOX is transiently effective, more immunotherapeutic agents are showing good responses. Avastin (bevacizumab) a vascular endothelial growth factor inhibitor and Erbitux effecting epidermal growth factor 1 are working well as is the newer Neo-102 against the immunogenic protein. Chemo in conjuction with the biologics (immunochemo) is the best combo. ...Read more
Chemo: Stage 4 colon Ca best handled by assuring that the primary is removed so other sites of spread don't appear. Systemic chemo then used for primary control but if lesions are in one area such as liver or lung, those sites approached if lesions small and resectable. If liver lesions get numerous then chemo embolization or Yt microspheres used. Thorascopic resection employed with some lung lesions. ...Read more
Across the board, Stage IV colon cancer is not a good thing to have. Statistically, the main survival with chemotherapy is about 2-3 years unfortunately. I have patients that are alive and relatively well on palliative chemotherapy after many more years. Every case is different and many options exists depending upon where the metastasis is located at. Usually Chemotherapy is the main treatme ...Read more
See your doctor: Have regular follow up with your family doctor and oncologist. Blood tests and yearly colonoscopy may be recommended. Sometimes ct scan is used if indicated. Please follow your doctor's recommendations, who will help direct you to the best tests for your specific condition. ...Read more
Depends: The answer to this question is highly dependent on the stage of the colon cancer when you had the surgery. Earlier stages have a low chance of recurrence, and those that may have spread deeper or to lymph nodes have a higher chance of recurrence. Chemotherapy is combined with surgery in some cases of colon cancer. ...Read more
Third infussion of oxyplatin stopped half way (half administered), can the treatment still Work? Metastic colon cancer
It can, but usually they want maximal effect because there is no guarantee the chemo will work
discuss the issue with your oncologist. ...Read more
Colon cancer pt. Surgery done. Aortocaval node contains a met. Is this dangerous? Can it cause issues? What best treatment for it?
If + is stage 4: With nodal disease a PET scan essential to RO other lesions. If solitary and hasn't responded to chemo then surgical reesection is important because of growth and invasion of aorta. We have resected portions of aora for such lesions. Newer therapy after chemo include mAbs like Neo 102 on FDA study. For chemo failure colon CA ...Read more
If someone got colon cancer and never got treatment of any sort, how long before they would show signs of being sick and how long would they live for?
A long time,,: This disease takes a while to develop like 20-30 years, unless it's associated with one of the polyp syndromes that cause it to appear much earlier. Usually it presents in the sixth decade of life (50-60) as fatigue and or change in bowel habits and abdominal discomfort. By this time it's usually advanced and 5 year survival is compromised. That's why colonoscopy is done for polyps at 50. ...Read more
When FOLFOX therapy (chemotherapy) has failed Immune reactive agents i.e. Avastin for blood vessel growth and Erbitux for epidermal growth factor have been applied as well as agents affecting tyrosine kinase.
The Immunogenic protein that acts as a vaccine isolated, a is a byproduct of oncofetal protein MUC5ac in its post translational form. In stage IV used to produce mAbs for strong ADCC. ...Read more
Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more
Kras braf tests are: Molecular testing of colon mets tissue for gene mutations of those two loci predict patients who will or will not respond to precision anti tumor (epidermal growth factor receptor protein) antibodies. These were FDA okd and clinically proven in hundreds of tested and treated patients to be beneficial in survival. Oncologists versed with and pathologists who process these tumor tissues shld help U. ...Read more
A CEA rise upon starting irinotecan in person with colon cancer suggest treatment not working? Cea was Oct 8, dec 9, jan 10.
Very good question!: The answer's somewhat debated. 1st, CEA levels even in the presence of cancer r somewhat variable, so my 1st question is *how much* did the values rise? An increase of 1 mcg/L may not b significant, though an increase of 100 mcg/L is definitely so. Also, levels increase if u r around cigarette smoke. Lastly, CEA could be released from cancer cells as they die. TTYD (Oncologist) to interpret numbrs ...Read more
Can colon cancer is it bad if a aortocaval node contains a met? The primary colon tumor is removed already. What is best treatment here?
Mets are bad: Metastasis of any kind are a bad sign, because it indicates that the disease has spread. Metastatic disease may be treated with radiation or chemotherapy, but this will depend on specific patient factors. Solitary metastasis to the lungs or liver are sometimes removed surgically, but aortocaval nodes are probably too risky. ...Read more
He had done colon cancer operation, after chemotherapy treatment but has cancer percentage not reduce completely. Can he outcome from illlness?
Your question, uncle: Your question is not all that clear. Please write clearly when the cancer operation (? date) was done and what was the stage of his Cancer? Did he have chemotherapy before or after the operation and how is he doing now. His oncologist can address your questions also. But we need more details before we can help you. ...Read more
Still good prognosis: Stage ii still confined to wall of colon, most of the centers close 90% 5 yr survival rates along with chemo. Will have healthy normal life. ...Read more
The majority of stage 2 colon cancer patients are cured with the surgery alone.
A smaller group of stage 2 colon cancers have already spread, but are not evident in the specimen or during the imaging.
So the answer to your question is yes, they can, but close follow up is a must. ...Read more