Doctor insights on:
It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more
Not any more, mostly: Puva stands for "psoralen plus ultraviolet-a" - you take a drug called psoralen, which sensitizes your skin to long-wave uv light, then you go in a uv light box. It was used to treat psoriasis and other skin diseases, but in recent years it has largely been replaced by narrow-band uvb light treatment, which works better and avoids the risks of psoralen, such as sunburn and cataracts. ...Read more
22yr female. Experience the following symptoms: angioedema, chronic urticaria, anaphylaxis, bone/muscle pain etc, is this systemic mastocytosis?
Serum tryptase level: You're certainly describing an entity that sounds histamine mediated but of course can be due to other causes and mediators. Does she have urticaria pigmentosa? Have you done a serum tryptase level? To my knowledge the one definitive diagnostic is a bone marrow bx. The other lab i look at to asses a histamine mediated process is anti high affinityfc epsilon receptor antibodies. Any meds? ...Read moreSee 1 more doctor answer
Lip swelling: It is very important to find out what has caused the lip swelling. If it is an allergic reaction, stop taking whatever caused the reaction, and see your physician or an allergy specialist for an evaluation. Do not try and treat this yourself. Also see your dentist to see if there is a dental infection. ...Read moreSee 1 more doctor answer
Allegra (fexofenadine) allergy: I am not quite sure of the question. Allegra (fexofenadine) is a non drowsy antihistamine to treat symptoms of allergic or non allergic rhinitis. The symptoms include runny stuffy nose, sneezing, itchy and watery eyes. It can also help itching of the skin. If your question is not answered, please clarify the question. ...Read more