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Doctor insights on: Trazodone Lethal Dose

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What to do if I had 50 mg of trazodone two days ago and am still feeling the effects. How long does it take to wear off?

What to do if I had 50 mg of trazodone two days ago and am still feeling the effects. How long does it take to wear off?

That is my short ans: 50 mgm trazadone, 48 hours later you still have the effects.
You probably went to see an md with some complaints, which included sleep disturbance. He gave you trazadone and you sort of sleeping since then.
Time for total truth.
What else are you taking. .. ...Read more

Dr. Katharine Cox
319 Doctors shared insights

Desyrel (Definition)

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I take 100mg of trazodone but doesn't work as well now. Can I safely up the dose to 150 or 200?

I take 100mg of trazodone but doesn't work as well now. Can I safely up the dose to 150 or 200?

Bipolar D/O: Your additional patient information does say you are bipolar, but there are no mood stabilizers on your medication list. I would be cautious about raising your trazodone dose. Sleep disturbance can signify a hypomanic or manic episode developing, and you would not want to precipitate that. I encourage you to work with a psychiatrist on this, and find better treatments than trazodone alone. ...Read more

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For insomnia, is trazodone at a 25 mg dose adequate? At 50 mg I got a 'high'.

For insomnia, is trazodone at a 25 mg dose adequate? At 50 mg I got a 'high'.

Variable: Doses of Trazodone needed for insomnia are variable, and depend on the person plus other medications being taken. Please discuss this "high" with your prescribing physician. The 25mg dose may be helpful -- if you've tried it and it works, you have your answer. ...Read more

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How many trazodone 150mg hydrochloride tables would be too big a dose for an adult male?

How many trazodone 150mg hydrochloride tables would be too big a dose for an adult male?

More than Rx'd: No flippancy is intended. Trazodone is a remarkable medication that has helped many people find relief from anxiety and depression, but its effects are unpredictable. As a pathologist, my concern is with heart side-effects in an overdose setting, though I've read that these are rare even at the 600mg/day level. The greatest danger of a high dose is to the mind -- don't use without good guidance. ...Read more

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I started taking Trazodone for chronic insomnia. It worked great for 7 days. Then last night I took it, and even upped the dose, and got nothing. Does this mean it's never going to work again? Normal?

May continue to work: Trazodone may continue to work for you. I would keep trying it as it is one of the safest sleep medications. Sometimes your body just does not respond for one reason or another but this does not mean that it will not work in the future. Try these tips too 1)avoid caffeine for 12 hours before sleep 2) do not use any electronics 2 hours before sleep 3) do not exercise just before sleep ...Read more

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Can I use Trazodone extended-release low dose for sleep longer, because trazodone ir make me sleep 4 to 5 hours?

Can I use Trazodone extended-release low dose for sleep longer, because trazodone ir make me sleep 4 to 5 hours?

Trazadone: In a larger dose may help with sleep. One needs to watch for serotonergic syndrome however if taken along with Zoloft (sertraline) (listed as current med) ...Read more

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I took a small dose of Trazodone to help me sleep. I didn't know it interacts with Wellbutrin until I looked it up today. Am I going to be ok? I still

I took a small dose of Trazodone to help me sleep. I didn't know it interacts with Wellbutrin until I looked it up today. Am I going to be ok? I still

Psychiatric Medicati: Blood level of trazodone will ^ on this med combo. Chance of seizures may also occur. BUT, this combination is used together often. There is a potential for a drug interaction but that does not mean that one will occur. You will likely be fine. Try not to worry. Make sure that you only take psychotropic medications that were prescribed for you. ...Read more

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I take trazodone1x50mg at night and low-dose Ambien (zolpidem) taken as needed. Trazodone doesn't seem to get me to sleep; may I add half an ambien (zolpidem)?

See below: Questions about changing medications or doses of current meds are best addressed to the doc who proscribed them. A more natural option might be the addition of melatonin before bedtime. Discuss with doc. Also important to ascertain cause (s) of insomniastress, caffeine, nicotine, alcohol, eating too much too late, noisy environment, bright lights. Establish sleep regimen. ...Read more

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Just put on 50mg trazodone, take 36mg concerta, & 1/2 of a 50mg tramadol 4 x day (100 total am weening off). Doc said its ok since low doses. Is ok?

Just put on 50mg trazodone, take 36mg concerta, & 1/2 of a 50mg tramadol 4 x day (100 total am weening off). Doc said its ok since low doses. Is ok?

Depends: Only your dr knows the answer. Med. Doses are calculated carefully and depend on the nature of your symptoms and how you have responded to meds so far.
Ps tramadol is an opioid medication that can cause dependence / addiction. ...Read more

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How long should I wait to begin Prozac (fluoxetine) after taking a single non-repetitive dose of Trazodone to avoid elevated risk of serotonin syndrome?

How long should I wait to begin Prozac (fluoxetine) after taking a single non-repetitive dose of Trazodone to avoid elevated risk of serotonin syndrome?

Ask your doctor: According to your profile, you're pregnant so please check with your OB to make sure both meds are ok to take. Not sure what "non-repetitive" Trazodone dose means. Do you mean "as needed for"? what you don't say. Good you're cautious about taking these meds especially if pregnant. Don't know doses so best to check also with your prescribing doctor if that person isn't your OB. Hope this helps. ...Read more

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Taking trazodone with prazosin my doctor recently diagnosed me with combat related ptsd which have been causing nightmares. While waiting to see a psychologist she prescribed low dose prazosin and low dose trazodone for the time being. I was researching b

Taking trazodone with prazosin my doctor recently diagnosed me with combat related ptsd which have been causing nightmares. While waiting to see a psychologist she prescribed low dose prazosin and low dose trazodone for the time being. I was researching b

Several: Several studies and case reports suggest that prazosin can benefit individuals with ptsd in reducing sleep disturbances and nightmares. Daytime prazosin has been reported to reduce distress related to trauma cues. However, as you correctly pointed out, taking trazodone and prozosin together could cause undesirable side effects. Why? Both drugs act on so-called alpha-1 adrenergic receptors causing their blockade. This often results in hypotension or drop in blood pressure, especially when the person rapidly changes his or her body posture. This could result in dizziness and sudden increase in the heart rate. Both drugs could also cause excessive sedation. If you already taking medications for high blood pressure, prazosin and trazodone may potentiate their action, causing undesirably low blood pressure. However, the final decision in recommending both prazosin and trazodone rests with your physician who examined you and knows your medical history. Hope this information helps but please do not hesitate to contact my office if you have further questions. ...Read more

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What is desyrel (trazodone)?

Desyrel (trazodone): It is the brand name for trazodone, an antidepressant which is mainly used to help people sleep. Only doses above 400mg has antidepressant effects but that would usually cause so much sleepiness that it is not used at all for depression. Most people sleep well at 100mg or below. A minority needs up to 450mg to sleep well, but they have other severe mental problems also. ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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How should you use trazodone?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Trazodone: Usually at bedtime, & as prescribed by your doctor, due to sedative effect. ...Read more

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Can you overdose on trazodone?

Can you overdose on trazodone?

OD: People can overdose on any medicine. Getting the depression treated gives people a second chance to excel at what they are good at. ...Read more

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Is trazodone a safe medication.

For most, yes: If prescribed and followed by a doctor, trazodone can be very safe. It's often used to help with sleep these days, rather than using it for its antidepressant features alone. It can cause dry mouth, dizziness, and nausea -- also in men, it can cause priapism at higher doses. ...Read more

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What kind of drug is trazodone?

What kind of drug is trazodone?

Trazodone: Is an antidepressant with known anticholinergic & sedative properties, leading to sleep & drying effects. ...Read more

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What is trazodone used to treat?

Trazodone: Trazodone is indicated for major depressive disorder and insomnia. ...Read more

Trazodone (Definition)

Is an antidepressant with known anticholinergic & sedative properties, leading to ...Read more