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Doctor insights on: Trastuzumab Gastric Cancer

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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Dr. Barry Rosen
4,357 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Stomach cancer treatment?

Stomach cancer treatment?

Surgery & Chemo: Early stage cancer may be treatable with surgery. Usually treatment is a combination of surgery and chemotherapy. ...Read more

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Esophegeal cancer markers?

Esophegeal cancer markers?

Not for early CA: Unfortunately , non to detect very early stages ca 125 , ca 19.9 , cea will be elevated at later stages, used to monitor the disease. Ca 72.4 cyfra 21.1 being tested .Scca (also for ca of cervix other squamous ca ). ...Read more

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Chemo drugs for lung cancer ?

Chemo drugs for lung cancer
?

Yes: Depending on the stage, how advanced the disease is and what type of lung cancer it is, chemotherapy can play a major role in treatment of lung cancer. ...Read more

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Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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What stage colon cancer is pt4a pn1c?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
What stage colon cancer is pt4a pn1c?

T4aN1c M?: Any evidence of spreading to other organ? If no spread- t4an1 means- stage 3b cancer. If evidence of sprading to other organ- it is a stage 4. ...Read more

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Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Abdominal carcinamatosis from breast cancer metastasis?

Abdominal carcinamatosis from breast cancer metastasis?

Could Be: You have a known breast ca? Any other mets? Typically, one would expect mets to bone before abdomen. If pathology on both sites is the same then probably mets. If not, possible second primary (like ovary). Good luck. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Tell me the metastatic triple negative breast cancer survival rates?

Tell me the metastatic triple negative breast cancer survival rates?

Depends: Survival rates depend on multiple factors; age, response to treatment, stage of disease, your overall health. This is a conversation best had with your medical oncologist. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?

DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?

It depends: It may depend on your age. Radiotherapy to your involved breast may be required as it is the standard of care. Ask your doctor and let us know what advice you receive. Tamoxifen is another medication recommended after completion of Radiotherapy. ...Read more

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Does breast cancer increase colon cancer risk?

Does breast cancer increase colon cancer risk?

Rarely.: Some hereditary mutations may increase the risk of both breast and colon cancer. Nevertheless, the majority of all breast and colon cancers are not hereditary. ...Read more

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Is pancreatic cancer curable?

Is pancreatic cancer curable?

Sometimes: Typical pancreatic cancer (adenocarcinoma) is sometimes, but only rarely, curable. It is usually diagnosed in an advanced state making cure with surgery less likely. If relatively localized, chemotherapy and radiation therapy can improve survival time. ...Read more

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Is pancreatic cancer curable?

Is pancreatic cancer curable?

Yes/no: It's one of the worst cancers and the cure rates are low. It also depends on the stage and location of the tumor. Some early detected cancers with a tumor location away from the duodenum and biliary pathways carry better prognosis than other types. Also, the longer the tumor doesn't give out metastasis, the higher the chance of cure. ...Read more

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Dr. Craig Lum Dr. Lum
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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Dr. Craig Lum Dr. Lum
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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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What does herceptin (trastuzumab) do for breast cancer patients?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
What does herceptin (trastuzumab) do for breast cancer patients?

Herceptin (trastuzumab) : Herceptin (trastuzumab) is one of targetted therapy that we can use to treat a her2 positive breast cancer. There are other her 2 receptor inhibitors out there- such as lapatinib, Pertuzumab and hopefully tdm1. It is able to stop the cancer from growing and ultimately cause death to cancer cells that have the her2 receptors. ...Read more

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What are risks of the cancer drug herceptin (trastuzumab)?

What are risks of  the cancer drug herceptin (trastuzumab)?

Several: Herceptin (trastuzumab) is remarkably well tolerated. The most common side effect is a decline in the pumping ability of the heart (called the left ventricular ejection fraction), possibly leading to congestive heart failure. Thus, people getting Herceptin (trastuzumab) should have an echocardiogram done before, and about every 3 months while on herceptin (trastuzumab). Most of the time, the heart recovers after the Herceptin (trastuzumab) is stopped. ...Read more

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Is there a possibilty of cancer metastases while herceptin (trastuzumab) session is still on going ?

Is there a possibilty of cancer metastases while  herceptin (trastuzumab) session is still on going ?

Yes: To start with her 2 positive breast cancers are very aggressive tumors, due to over expression of her 2 gene ( makes her 2 protein causing uncontrollable growth ) Herceptin (trastuzumab) , a monoclonal antibody controls that growth , it is possible tumor can spread simultaneously during course of treatment. ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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Could herceptin (trastuzumab) be used for other types of cancer such as brain tumors?

Herceptin (trastuzumab): ... Is used in malignancies that over-express the her2 protein. It was initially approved for breast cancer, now also approved for use in her2 + gastric cancer. I would guess there is research with it in other cancer types but to my knowledge those are the 2 cancers for which it would be covered. Thank you for your service. ...Read more

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How effective is trastuzumab for treating breast cancer?

Variable: Requires that the tumor has the oncogene Her-2-Neu. If that oncogene is present (it will be recorded on the pathology report that has the estrogen/progesterone receptor results) then trastuzumab may be very effective. If the oncogene is absent then trastuzumab will not help. ...Read more

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more

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Is herceptin (trastuzumab) just can heal breast cancer?

Is herceptin (trastuzumab) just can heal breast cancer?

Herceptin (trastuzumab): Herceptin (trastuzumab) is approved for the treatment of early-stage breast cancer that is human epidermal growth factor receptor 2-positive (her2+) and has spread into the lymph nodes, or is her2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (er/pr)-negative or have one high risk feature. ...Read more

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Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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What do I need to know about herceptin (trastuzumab) after breast cancer?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
What do I need to know about  herceptin (trastuzumab) after breast cancer?

Herceptin (trastuzumab): Herceptin (trastuzumab) is a targetted therapy that inhibits her2-neu receptor . Herceptin (trastuzumab) has been given to patient with her2neu receptor positive breast cancer with improvement of response and survival. Herceptin (trastuzumab) has been also one of treatment options for her2 reeptor positive stomach cancer. Read. Mire about Herceptin (trastuzumab) at www.Cancer.Net, www.Cancer.Org, www.Nccn.Com. ...Read more

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Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Herceptin (trastuzumab) breast ca: About 1/4 cases of breast cancer express a protein on the surface of the cancer cells called her2neu which is a member of the epidermal growth factor family of receptors important for growth signaling into the cell nucleus. Herceptin (trastuzumab) is an antibody developed to target her2neu and antagonize this growth signaling and kill the cancer cell. Chemo is synergistic with Herceptin (trastuzumab) when given together. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Does being on herceptin (trastuzumab) for breast cancer cause you to gain weight?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
Does being on herceptin (trastuzumab) for breast cancer cause you to gain weight?

No: Herceptin (trastuzumab) is not associated with weight gain. However sometimes weight gain can happen during or following chemotherapy due to the use of steroids prior to chemotherapy. However not related to Herceptin (trastuzumab) use. ...Read more

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Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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What does herceptin (trastuzumab) do for breast cancer patients?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:

Herceptin (trastuzumab) : Herceptin (trastuzumab) is one of targetted therapy that we can use to treat a her2 positive breast cancer. There are other her 2 receptor inhibitors out there- such as lapatinib, Pertuzumab and hopefully tdm1. It is able to stop the cancer from growing and ultimately cause death to cancer cells that have the her2 receptors. ...Read more

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Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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Why is herceptin (trastuzumab) licensed for use of advanced but not early breast cancer?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
Why is herceptin (trastuzumab) licensed for use of advanced but not early breast cancer?

Used in both setting: For your information, Herceptin (trastuzumab) is used and indicated for both settings- for early breast cancer- at least is given for 1 year - as well as for advanced metastatic breast cancer. ...Read more

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Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read more

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Is there any oral maintenance medicine fot her2 breast cancer after finishing the herceptin (trastuzumab)?

Is there any oral maintenance medicine fot her2  breast cancer after finishing the herceptin (trastuzumab)?

Hormonal treatment: If the cancer is er positive then tamoxifen or an aromatase inhibitor would be beneficial to reduce the risk of recurrence. ...Read more

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How long does 18 infusions of herceptin (trastuzumab) cover you for breast cancer grade 3 her+3 stage 1?

How long does 18 infusions of herceptin (trastuzumab) cover you for breast cancer grade 3 her+3 stage 1?

Hopefully forever: In the us, the studies of Herceptin (trastuzumab) looked at a full year of treatment for patients with curable breast cancer. Herceptin (trastuzumab) is given every three weeks for 17 doses. But why a year? It was chosen at random. In finland, a similar study gave only 9 weeks of herceptin (trastuzumab)... And patients did just as well! so, after a year (or less) you are considered cured. You don't need more! ...Read more

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What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

?: I have never had an issue of trastuzumab (herceptin) coverage in appropriate patients. Individual co-pays are based on each patients insurance. There may be a benefit of trastuzumab in 0/low expression breast cancer that is the subject of a cooperative group clinical trial -- nsabp b-47 - clinicaltrials.Gov id: nct01275677. ...Read more

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Im a her2 stage 3 breast cancer parient . I have already finished my herceptin (trastuzumab) what would be the next medication would I take as maintenance medicine?

Im a her2 stage 3 breast cancer parient . I have already finished my herceptin (trastuzumab) what would be the next medication would I take as maintenance  medicine?

It depends on your b: There are many medicines used to treat breast cancer. Besides herceptin, (trastuzumab) your doctor may prescribe chemotherapy or hormonal therpy depending on the subtype of breast cancer that you have. Hormonal therpies are used for er+ cancers....So check if your tumor wass er+ or er-. Ask you oncologist to address this question. ...Read more

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Dr. Brad Goldenberg
58 doctors shared insights

Trastuzumab (Definition)

Trastuzumab is an antibody based agent which is a kind of ...Read more


Gastric (Definition)

This refers to something that is ...Read more