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Doctor insights on: Tranxene Overdose

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What is the treatment for tranxene (clorazepate) overdose?

What is the treatment for tranxene (clorazepate) overdose?

Support: A specific antidote for benzodiazepine, such as tranxene (clorazepate), (clorazepate) overdose exists. This is usually available in hospital emergency rooms. Because tranxene (clorazepate) causes sedation, impaired swallowing and shallow breathting it is important to lay the person down, keep warm, ensure that breathing is maintained (loosened collars or even mouth-to-mouth breathing is serious cases) use fluids cautiously!

Dr. Bernard Seif
30 Doctors shared insights

Clorazepate (Definition)

Clorazepate (brand name tranxene) is a benzodiazepine (minor tranqilizer). Its active metabolite is desmethyldiazepam, which has a long half life in the body. It is not frequently used today as a tranquilizer, because it is fairly sedating, but is mostly used in the treatment of ...Read more


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What is the definition or description of: Tranxene (clorazepate) overdose?

What is the definition or description of: Tranxene (clorazepate) overdose?

Varies with dose: There are degrees, related to how much taken. At slight overdose, these is sleepiness, and perhaps some "drunkenness, " with poor judgment, imbalance, slurred speech. At higher doses, sleeping, but temporarily rousable. At higher doses, coma. Although respirations and blood pressure are reduced then, it typically is only lethal when overdosed in combination with something -- especially alcohol.

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What is the treatment for tranxene (clorazepate) overdose?

Support: A specific antidote for benzodiazepine, such as tranxene (clorazepate), (clorazepate) overdose exists. This is usually available in hospital emergency rooms. Because tranxene (clorazepate) causes sedation, impaired swallowing and shallow breathting it is important to lay the person down, keep warm, ensure that breathing is maintained (loosened collars or even mouth-to-mouth breathing is serious cases) use fluids cautiously!

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Can someone overdose quickly on tranxene (clorazepate)?

Yes, but not quickly: Like any medication in its group, it is lethal in overdose. The problem with tranxene (clorazepate) is that people do not feel affected by it right away, and can continue taking more and more in quick succession. After a few hours, however, they realize that they are too sedated, but cannot quickly get it out of their body.

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Is there a tranxene (clorazepate) 1 mg?

Is there a tranxene (clorazepate) 1 mg?

No.: The brand drug tranxene (clorazepate) is discontinued in the U.S. However, the generic form is still made. The lowest dose is 3.75 mg tablets. It also comes in 7.5 and 15 mg strength tablets. You could try breaking a 3.75 mg tablet in half if needed.

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What is the duration of tranxene (clorazepate)?

Long acting: Tranxene (clorazepate) is very long acting. It's half life is 40-50 hours. That means it can take 2-4 weeks to fully be out of your system.

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Tranxene (clorazepate) withdrawal?

Tranxene (clorazepate) withdrawal?

Can Be Serious: It depends on the length of time the person took tranxene (clorazepate) and the daily dose. If a person takes tranxene (clorazepate) everyday for at least month, he or she may have mild to moderate to severe withdrawal symptoms, again depending on the daily dose. The symptoms would be anxiety, irritability, tremors, insomnia and even withdrawal seizures. It is important to discuss slowly tapering off with your doctor.

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Tranxene (clorazepate) vs. Valium what is better?

Tranxene (clorazepate) vs. Valium what is better?

Whatever works: Either drug may be effective. Both are benzodiazepines. Both have strongly addictive profiles. Both are respiratory depressants and mood depressants. Both are significantly augmented by alcohol consumption. The less you take of a "benzo" the better off you are. This class of drugs needs frequent monitoring to avoid problems.

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I was prescribed Tranxene (clorazepate) and Brintellix at the same time. Are the benefits better together? What are the benefits of each? Hard to find info on them.

New items: These are among the more recent products and do not have any bad problems when taken together. Tranxene (clorazepate) is for anxiety, Brintellix for depression. Check for info at drugs. Com - they are both there and there are reviews + info. Best wishes!

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Does tranxene (clorazepate) work?

Yes: Tranxene belongs to the same group as xanax, (alprazolam) ativan, etc. It is, however, very long-acting: it starts slowly, but stays in the body for a long time. People who get used to short acting drugs expect tranxene to work quickly, so might think it doesn't work. The equivalent dose is also important. It works great for anxiety or alcohol/benzo withdrawal.

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Does tranxene (clorazepate) work right?

Sure: I hope your question was, "does tranxetne work. Right? " this medication belongs to the same family as Xanax (alprazolam), (alprazolam) Valium, etc. It is doing practically the same. It is just much longer acting and much slower to start acting. Because of this, people experienced with more immediately working medications do not feel it is working. Give it time. Do not expect to feel the same as Xanax (alprazolam).

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How long does it take tranxene (clorazepate) to work?

Short Time: I would expect the effects of this medication to be felt in one to two days after starting it depending on how much and how often it is taken. If it is not being helpful, please contact your prescriber and discuss this with him/her.

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How long does tranxene (clorazepate) take to remove all symptoms?

Variable: Dependent on what the symptoms are, the strength of the medication taken, and the rate your body metabolizes medication. None of these questions can be answered on this format with the input you have given. You will need to see your DR to get answers.

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How long does it take for tranxene (clorazepate) to start working?

15 minutes at least: Tranxene (clorazepate) is only available orally. Thus it will probably not reach effective blood levels sooner than 15 minutes. Results depend on person's general health, age, gender, fever, other drugs used (including alcohol and tobacco), and medical condition being treated.

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I've been taking Tranxene (clorazepate) for a few days. When should I feel it start to work?

Add therapy?: The anti-anxiety effects of a tranquilizer such as Tranxene (clorazepate) usually begins to work in the first day. However many anxiety problems need more than just a pill. It may be best to see a psychiatrist who can not only adjust the medication but offer psychotherapy when needed.

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I was prescribed tranxene (clorazepate) 7.5 mg po at bedtime, but I only have tranxene (clorazepate) 3.75 mg tablets. How many tablets do I need to take?

Two, but talk to do: Obviously 3.75 +3.75=7.5 so the answer would be two. However there may have been a breakdown in communication between you and your doctor which led you to be in this situation when you don't know how your doctor wanted you to take your meds. It is also a good idea to talk with the doctor who prescribed the meds to be certain how he or she wanted you to take them.

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Is there a difference between tranxene vs xanax (alprazolam)?

Tranxene (clorazepate): They are both anxiety medications. Xanax is a short acting and tranxene (clorazepate) is long acting benzodiazepenes.

Dr. Mark Shukhman
30 Doctors shared insights

Tranxene (Definition)

Tranxene is a mouth/lip preparation which is a kind of ...Read more


Overdose (Definition)

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