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Doctor insights on: Transplant

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Dr. James Chapman
3 doctors shared insights

Transplant (Overview)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to prevent this (immunosuppressive medications).


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What is a mini-allo transplant?

What is a mini-allo transplant?

Low doses of chemo: Doctors want to capture the anti-tumor effect of the donor's immune cells and they do not need to totally kill all the patient's cancer cells at the time of transplant. These cells will do it over time. Therefore the transplant itself is not as dangerous as a full or standard transplant. However, the serious complications that occur from these same cells causing gvhd are still present. ...Read more

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Dr. James Chapman
3 doctors shared insights

Transplant (Overview)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to prevent this (immunosuppressive medications).


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How are organ transplants done?

How are organ transplants done?

See:: http://www.webmd.com/a-to-z-guides/organ-donation-facts

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Why are kidney transplants bad?

Why are kidney transplants bad?

They are not: Much better than indefinite hemo-dialysis or peritoneal dialysis ; far better than dying of uremia (kidney failure). Kidney transplants are associated with complications in many cases, but beefits of kidney transplants far outweigh the risks. ...Read more

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How can organ transplants work?

Healthy new organ!: When your own organ(s) don't work they fail to perform the key functions that keep you alive. Replacement parts (from another human) are connected to you. Medications are given to prevent your immune system from recognizing that these "new" organs have different DNA than you do, preventing rejection. Technical success + consistent use of medications (every single day!) = success. ...Read more

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How are kidney transplants done?

How are kidney transplants done?

Kidney transplant: Once the kidney is removed from the donor eithe living or cadaver, the kidney is placed through a lower abdominal incision iusually into the right side of the pelvis and attached the iliac vein and artery and ureter implanted into the bladder. ...Read more

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How common are kidney transplants?

How common are kidney transplants?

~17,000 a year in US: In 2013, there were 16,895 kidney transplants in the U.S. About 11,000 of them were deceased donor kidney transplants; the rest were living donor transplants. ...Read more

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What age is too old for transplant?

What age is too old for transplant?

No fixed age: It is hard to fix on a number because there are broad differences between two individuals. It is better to categorize the physiological age rather than the chronological age of a patient. The question to really ask is "does the risk of transplanting a solid organ outweigh the benefit of receiving that organ?" the answer can be subjective and viewed differently among professionals. ...Read more

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Who should get an islet transplant?

Who should  get an islet transplant?

Type 1 diabetics: Islets, the Insulin producin areas of the pancreas, can be transplanted for advanced type 1 diabetes, either in the form of a whole organ, or as islet cell transplants. Most islet cell transplant eventually fail, and, more worrisome, cause antibodies that make subsequent whole organ transplant difficult. The whole organ pancreas transplant is therefore currently the best option. ...Read more

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Who is eligible for organ transplants?

Depends: Eligibility and allocation varies by organs. For example, kidneys are allocated based on waiting time whereas liver, heart, lungs are allocated based on how sick the patient is. In general, active infections, recent history of cancers, and multi-organ failures might make a patient ineligible. ...Read more

Dr. Amy Friedman
1,109 doctors shared insights

Transplantation (Definition)

Transplantation is the process of transplanting organs from a donor to a recipient and includes surgery ...Read more