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Doctor insights on: Transient Neonatal Pustular Melanosis Wright Smear Of Lesion

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Lichen simplex chronicus pathology was done in 2008 saying;biopsy of skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory cell infiltrate composed of primari

Lichen simplex chronicus pathology was done in 2008 saying;biopsy of  skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory  cell infiltrate composed of primari

This : This is very challenging without a clinical examination. This could be lichen simplex chronicus, prurigo nodularis, or other possibilities. Certainly i would get it looked at to be sure so i would recommend you see a dermatologist to further evaluate the area. There are many treatment options to helps these conditions. I hope that helps! ...Read more

Dr. Barbara Lavi
1 doctor shared a insight

Neonatal (Definition)

The term neonatal is generally used to describe events that occur with an infant within the first 30 days after birth.Some practitioners are looser with the definition & extend the ...Read more


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Bruises on leg - derm biopsy report dx: vascular telangiectasias, sparse perivascular lymphocytic inflammation & hemorrhage. What does this mean?

Bruises on leg - derm biopsy report dx: vascular telangiectasias, sparse perivascular lymphocytic inflammation & hemorrhage. What does this mean?

The biopsy shows no: The biopsy shows nothing remarkable. I wonder why it was done. What was the DR looking for? Ask the DR who did it to interpret it for you. ...Read more

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What are the tests for transient neonatal pustular melanosis?

What are the tests for transient neonatal pustular melanosis?

Visual Diagnosis: This benign skin condition seldom warrants any tests. A scraping of the pustules reveals white cells & eosinophils without germs.The eruption pattern & lack of inflammation separate it from other entities. ...Read more

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Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

No: There is no involvement of the blood vessels themselves- thus not vasculitis by definition. This is a very common skin biopsy finding which has no diagnostic meaning other than ruling out a more serious condition. ...Read more

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Help understand skin biopsy result: "There is a sparse perivascular lymphohistiocytic inflammatory infiltrate. CD117 highlights only a few scattered mast cells. Diagnosis: Mild superficial perivascular infiltrate." Anything of concern here?

Help understand skin biopsy result: "There is a sparse perivascular lymphohistiocytic inflammatory infiltrate. CD117 highlights only a few scattered mast cells. Diagnosis: Mild superficial perivascular infiltrate."  Anything of concern here?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the findings listed in the report are non-specific and non-diagnostic. Do you have any symptoms? Why was the biopsy done? ...Read more

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Melanocytic Nevus with arch disorder and mild cytologic atypia of melancytes found from mole shave biopsy. what is the treatment for this?

Melanocytic Nevus with arch disorder and mild cytologic atypia of melancytes found from mole shave biopsy. what is the treatment for this?

Removal of nevus: Excision of mole is preferred method , it gives complete picture , not missing any area of potential malignant cells . Good news you don't have , but have atypical cells , so speak to your doctor for possible excision of whole mole and analyzing ( biopsy ) it. ...Read more

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What does it mean? Vulvar biopsy result( d/t reddness)/koilocytosis -suggestive early hpv induced lesion No dysplasia or malignancy identified

What does it mean? Vulvar biopsy result( d/t reddness)/koilocytosis -suggestive early hpv induced lesion
No dysplasia or malignancy identified

No worry: There is nothing to worry about. However, you should follow your doctor's advise about follow-up care. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. Get HPV vaccine. ...Read more

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Biopsy done on nodule by tonsil states "reactive lymphoid hyperplasia with focal squamous metaplasia." does that mean I have oral HPV (oral warts)?

Biopsy done on nodule by tonsil states "reactive lymphoid hyperplasia with focal squamous metaplasia." does that mean I have oral HPV (oral warts)?

Not necessarily: The description you provided only points to chronic inflammation without any indication of the causative factor. Hpv infection can be tested for specifically in a biopsy and you may wish to discuss that with your doctor. ...Read more

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Dysplastic nevus, or atypical moles, and they are benign lesions that resemble early melanoma, and about 1 in 10 million americans willmelanoma, what to do?

Dysplastic nevus, or atypical moles, and they are benign lesions that resemble early melanoma, and about 1 in 10 million americans willmelanoma, what to do?

Watch carefully: Dysplastic nevi are potentially serious in that they can convert to infiltrating melanoma. In children with spitz nevus, they look malignant but never convert. In patients with neurofibromatosis there is a high incidence of dysplastic nevi and since many are present they are watched for changes in shape, darkening in color or redness around the lesion suggesting that they are converting. ...Read more

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Pigmented lesion . In face..Recent increase size..Irregular border....Biopsy reveals malignant cells infiltration ...Whats diagnosis plz?

Pigmented lesion . In face..Recent increase size..Irregular border....Biopsy reveals malignant cells infiltration  ...Whats diagnosis plz?

Can be melanoma.: This sounds like melanoma. You're lucky to have found this out on biopsy, as removal of this can be 100% curative. It's really smart to talk this over with your doctor, as well as the treatment options so you know what you're dealing with. ...Read more

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Vulva biopsy results slight spongiosis with very sparse superficial non vascular lymphotic infiltrate what does that mean?

Vulva biopsy results  slight spongiosis with very sparse superficial non vascular lymphotic infiltrate what does that mean?

What did your GYN sa: Whomever did your biopsy is supposed to explain what it means and what the implications are, that is your doc's responsibility and if your doc does not understand what that means he or she can speak with the pathologist who read the slides and if u do not understand what your doc says then u need to let yoru doc know, without seeing the report most likely you have a dermatitis which can be treated. ...Read more

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Do I have oral HPV (oral warts)? Biopsy diagnosis states "reactive lymphoid hyperplasia with focal squamous metaplasia" what does this mean?

Chronic inflammation: The description you provided only points to chronic inflammation without any indication of the causative factor. Hpv infection can be tested for specifically in a biopsy and you may wish to discuss that with your doctor. ...Read more

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Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Seek 2nd opinion: Recurrence of a mole makes it likely that it is a melanoma. You should get further surgery done by a melanoma expert(surgical Oncologist). It always useful to seek 2 or 3 opinions and go with the aggregate of the recommendation, provided to you. ...Read more

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What does this mean: urticarial change including deep dermal fibrosis with underlying morphea and telangiectasia with melanin incontinence?

What does this mean: urticarial change including deep dermal fibrosis with underlying morphea and telangiectasia with melanin incontinence?

Talk to derm: From what i can see, the skin rash is from hives and the scarring from scratching. I have never heard of the term melanin incontinence so I have no idea what it means. The best thing is for you to discuss this with the derm doctor who did the biopsy. ...Read more

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Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more

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Dear Sir FNAC result "Smear consists of fibrofatty tissue with few lymphocytes and polymorphs suggestive of inflammed lipomatous lesion"?

Dear Sir
 FNAC  result  "Smear consists of fibrofatty tissue with few lymphocytes and polymorphs suggestive of inflammed lipomatous lesion"?

May need core biopsy: FNAC is often inadequate to make a proper diagnosis, especially if you suspect cancer. if you have a tumor, you should go and see a good surgeon who deals with cancer. He may do a core biopsy which gives more tissue than a FNAC. I am afraad you will need a repeat biopsy but seek a second opinion for finding out what you have wrong ...Read more

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What are the tests for transient neonatal pustular melanosis?

Visual Diagnosis: This benign skin condition seldom warrants any tests. A scraping of the pustules reveals white cells & eosinophils without germs.The eruption pattern & lack of inflammation separate it from other entities. ...Read more

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What is pustular melanosis in infants and how is it treated?

What is pustular melanosis in infants and how is it treated?

Transient change: This is a transient skin condition of unknown origin.It presents in a fraction of infants with tiny blisters, pustules or open blisters with a scaley margin. The blisters or pustules are usually gone by 5 days but the pigmentary change may last for weeks to a few months. They resolve without treatment so no treatment is recommended. Exclusion of other conditions is part of the evaluation. ...Read more

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What is the definition or description of: Newborn freckle rash?

What is the definition or description of: Newborn freckle rash?

Pustular melanosis: There is a condition where the fetus has a rash while in the womb that is tiny little pustules. They pop, but then leave a tiny spot of pigmentation where they were. When baby born those spots almost look like freckles, but baby has never had sun exposure! Usually fades away over the first few months of life - rarely is it a permanent rash. ...Read more

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What are the symptoms of newborn freckle rash?

What are the symptoms of newborn freckle rash?

??freckle rash ??: Thats a new one for me. Perhaps u are describing a rash called transient neonatal pustular melanosis that comes up as small pustules without inflammation & leaves brownish pigment as it fades.The pigment will fade over ~3m. ...Read more

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What is the treatment for newborn freckle rash?

What is the treatment for newborn freckle rash?

Nothing: Babies get several skin rashes (their skin is very delicate and reacts to everything). The little pimples on the face will go away without any treatment. Wash his face with plain water, no soap, and don't use any creams or medicines on his face, unless your doctor recommends them. ...Read more

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Can Alli produce melanosis in the colon?

Can Alli produce melanosis in the colon?

Not usually: Melanosis coli occurs with chronic laxative use, specifically the ones that have anthraquinone to cause pigmentation in the walls. It is a benign condition. As far as i know, Alli has no empiric or theoretical reason to cause this. ...Read more

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Can other medicines cause melanosis coli?

Can other medicines cause melanosis coli?

Yes: Although pathology textbooks focus on cascara laxatives as the cause of blackening of the colon mucosa by pigment in macrophages, the truth is that any laxative that works by damaging the colonic epithelium can do the same thing. ...Read more

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Is melanosis a type of cancer?

Is melanosis a type of cancer?

Melanosis Coli: I think you are referring to melanosis coli. This is a discoloration of the inner lining of the colon, which is not cancerous, but can make it difficult to notice irregularities. ...Read more

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Can taking rifampicin cause melanosis coli?

Can taking rifampicin cause melanosis coli?

Med side effect: Doubtful. Melanosis coli is very common and can occur more frequently in females, those who use laxatives or who have inflammatory bowel disease. In general it can just happen so no need to try and see if a medication caused it. Speak to your md for more details if you are concerned but you may just "have it for no reason". ...Read more

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What exactly is melanosis cutaneous fibromatosis?

What exactly is melanosis cutaneous fibromatosis?

Disease: Depends where the lesion is. Likely it is a benign tumor (fibroma) that has skin color changes (melanosis) that need to be followed and biopsied on a regular basis. Autoimmune disease might also be a contributing factor. Ur dermatologist could best answer this. ...Read more

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Can conjunctival melanosis present with tortuous conjunctival vessels?

Can conjunctival melanosis present with tortuous conjunctival vessels?

Different things: Primary conjunctival melanosis is a brown discolored spot in the eye that resembles a freckle or somewhat scatter. It is consider precancerous. Vessels in the conjunctiva might be tortuous or not. ...Read more

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What is a melanosis coli?

What is a melanosis coli?

Coloration of colon: The inside lining of the colon can become darkened oftentimes from laxative use but it is a benign finding seen on colonoscopy. ...Read more

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How do I cure labial melanosis?

How do I cure labial melanosis?

Dermatologist: See a dermatologist for treatment options. Bleaching treatments are available. Also discuss what may be causing the dark pigmentation such as oral contraceptives or other medications. ...Read more

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Is there any homeopathic treatment for neurocutaneous melanosis?

Is there any homeopathic treatment for neurocutaneous melanosis?

Homeopathy: Homeopathy is an older treatment method, where small amounts of a substance that produce a symptom, are used to treat the symptom in microscopic amounts. Homeopathy is very popular in europe and is still in use all over the world. Homeopathy is symptom based and they do not "treat" named diseases. ...Read more

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I just had a colonoscopy this morning and they found melanosis coli. I look up =abusive use with laxatives.I do not use laxatives. What else causes?

Melanosis coli: If the diagnosis is correct is caused by cascara segrada an ingredient in many over the counter laxatives, softeners and herbal remedies. It causes deposits of pigment in the mucosal cells giving a black or leopard skin appearance to the colon lining instead of the natural pink appearance, it does not pose any medical risk but it does make diagnosis of colon pathology somewhat difficult. ...Read more

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It seems I have Penile lentiginosis. I don't think it is Penile melanosis cause of my age,18, and no sexual activity. Is there any treatment possible?

It seems I have Penile lentiginosis. I don't think it is Penile melanosis cause of my age,18, and no sexual activity. Is there any treatment possible?

See a dermatologist.: A dermatologist can diagnose and treat your condition. If you are correct, and these spots are benign lentigos, topical treatments include hydroquinone, azelaic acid, corticosteroids, and tretinoin. Laser surgery can provide definitive treatment. The dermatologist can provide accurate diagnosis and definitive treatment. Take care. ...Read more

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What does ocular melanosis mean? My baby has dark spots on whites of eyes. Could it be a disease? His vision is 100% and his health is generally good

What does ocular melanosis mean? My baby has dark spots on whites of eyes. Could it be a disease? His vision is 100% and his health is generally good

Descriptive label: The label is a descriptive one meaning the eye surface contains recognized areas of melanin pigment with an unusual pattern. It is usually a benign condition and varies in frequency within several ethnic groups. About 1/20 have a risk over their lifetime of a transformation into a dangerous form of cancer. Regular checkups with an eye doc can recognize the need for treatment if it is ever needed. ...Read more

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I was told I have melanosis coli. I take daily herbal supplements to help with chronic constipation. Is this bad?

I was told I have melanosis coli. I take daily herbal supplements to help with chronic constipation. Is this bad?

Benign: Melanosis coli is a benign condition that causes yellowish discoloration of colon that occurs due to excessive use of plant based laxatives such as senna. It is not associated with any serious condition. ...Read more

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Dr. Scott Bolhack
802 doctors shared insights

Wounds (Definition)

Wound = injury to tissue. May include ...Read more