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Doctor insights on: Transduction Laboratories Antibodies

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Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" what does that mean in real terms?

Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" 
what does that mean in real terms?

Not diagnostic: In general, lab tests are used to support a clinical diagnosis and thus a positive test per se does not provide a diagnosis without abnormal physical findings or symptoms. On many occasions, an abnormal lab test is not associated with any disease condition especially when the value is only slightly abnormal. If you do hundreds of tests on a healthy person, you will likely find something abnormal. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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What to do if I had a level or value of 266 for a DNA antibodies, native lab test. does anyone know what that means?

What to do if I had a level or value of 266 for a DNA antibodies, native lab test. does anyone know what that means?

Insufficient info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you have not provided enough information for a meaningful opinion. DNA antibody tests are usually done in autoimmune diseases like Lupus. ...Read more

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Had lab test done. Sm/rnp antibody 2.5 pos. What does this mean?

Had lab test done.  Sm/rnp antibody   2.5 pos.   What does this mean?

Probably nothing: That low titer is not impressive, usually the RNP. Ask the doctor who ordered it. Why was the test ordered in the first place? ...Read more

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Been on thyroid meds for 2 yrs recently got lab results with greater than 1000 antibodies, what could be wrong?

Been on thyroid meds for 2 yrs recently got lab results with greater than 1000 antibodies, what could be wrong?

Thyroid antibody: The high thyroid antibody test means you have an autoimmune destruction if your thyroid called hashimoto's thyroiditis. This test will stay positive even when you are taking the correct dose of thyroid hormone. Your level is good when the TSH blood test is normal at about 0.5 -3 miu/l. ...Read more

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When a lab test only tests for "phospholipid antibodies" & doesn't say which phospholipid antibodies in particular, how is the test even useful?

When a lab test only tests for "phospholipid antibodies" & doesn't say which phospholipid antibodies in particular, how is the test even useful?

Incr. chance clots: Individuals who have antiphospholipid antibodies such as lupus anticoagulant are prone to increased likelihood for blood clots. A pregnant individual with this/these have a higher likelihood of miscarriage. Anticoagulants are smart to do (or give prolonged courses) in individuals who have this and a compatible history/clinical situation. ...Read more

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My 13 y/o daughter has type 1 dm she had a lab test named ia-2 antibody her result came back <0.8 what does this mean?

My 13 y/o daughter has type 1 dm she had a lab test named ia-2 antibody her result came back <0.8 what does this mean?

Negative test?: Without having the normal range, it is hard to know but generally a "less than" level means it is below what the lab equipment can identify. An ia-2 test measures antibody against components of Insulin producing cells in the pancreas. It is only one of several antibodies that can be associated with type 1 dm. She may well have another antibody test that is positive. ...Read more

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Pleaseexplaintest result:sjogren's sa value is 3 . Lab ref. Range anything below20is negative, but why when those antibodies shouldn't be in blood?

Pleaseexplaintest result:sjogren's sa value is 3 . Lab ref. Range anything below20is negative,  but why when those antibodies shouldn't be in blood?

Antibody test: Testing for antibodies isn't like counting sheep. We test for biological activities -- molecules attaching to a substrate. There's usually some measurable activity -- whether it's even one of the true ssa antibodies is moot. Everybody has bazillions of different antibodies in the blood at low levels for no obvious reason. Be glad of a negative anti-ssa and continue your workup. ...Read more

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My lab tests came back with a positive ANA and positive rnp antibodies...Are these normal ?

My lab tests came back with a positive ANA and positive rnp antibodies...Are these normal ?

No.: Positive anas can be "false" positive. On the other hand an rnp antibody is not false. This combination would indicate mixed connective tissue disease. That having been said, I have many patients with a low titer rnp positivity and no signs of disease. ...Read more

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On antibiotics for bacteremia for 2 wks., how long for SED rate to go down? It was 23 last week and down to 19 now. (lab range is 0-15)

On antibiotics for bacteremia for 2 wks., how long for SED rate to go down? It was 23 last week and down to 19 now. (lab range is 0-15)

Well the sed rate: gives you a hint of what the inflammation from infection in your body is doing, but it should not be an indicator of whether the infection is eradicated. Repeat blood cultures and clinical picture are what you use to track infection progress. Sed rate is a temporary, if lukewarm, indicator at best. ...Read more

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