Doctor insights on:
Intolerance: An undesirable/uncommon effect of Topotecan could be due to allergy. Most allergic reactions manifest as skin rashes which are generally itching and sometimes urticarial in nature. A sudden drop in BP after an initial few drops of medication would be very suggestive of an allergic reaction. Nausea/vomiting are an expected side effect of chemotherapy, so that would not be an allergy. ...Read more
Hopefully: I have seen many chemo agents over the past 20 years cause musculoskeletal problems. I must say that the majority of those problems such as pain do go away. The problem is there is no definite time frame. I have seen pain resolve within weeks to a year. You always want to make sure there is no other cause for the musculoskeltal complaints. Good luck. ...Read more
My mother was administered topotecan and is now suffering from severe worsening diarrhea and low WBC count. Medicines for diarrhea require wbc. Help!?
Ov cancer spread to lymph nodes. Paclitaxel, avastin, (bevacizumab) doxil, gemzar, topotecan have failed. Is it all down hill from here? Is this the end?
Not yet: Ovarian cancer can best be managed by minimal tumor burden an then intraperitoneal chemotherapy. If there is a well defined chain of nodes such as the iliac nodes, I do a pelvic node dissection. L if the tumor burden represents additional multiple nodules along the surface of the bowel, they must be reduced to smaller than 1cm. In diameter. In addition it is essential that the omentum is out.Ea. ...Read more
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
So call your doc: This is the HT public information site.We are thousands of volunteer docs based primarily in the US who answer medical questions.We do not offer treatments. State medical boards require a physician/patient relationship,a retrievable record,recent exam with vital signs for prescribing.Failure to do so can lead to loss or restriction of license. It may seem minor to you but it is not. ...Read moreSee 1 more doctor answer
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more