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Doctor insights on: Topotecan Chemotherapy

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

Dr. Devon Webster
977 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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How is chemo drug - docetaxel (taxotere)?

How is chemo drug - docetaxel (taxotere)?

?: Sorry but your question makes no sense. What do you want to know about docetaxel? ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Is rituxan (rituximab) considered a chemotherapy drug?

Is rituxan (rituximab) considered a chemotherapy drug?

Not really: Rituxan (rituximab) is used to treat certain cancers as well as other non-cancer conditions. In the oncology world, we don't think of it as "chemotherapy" because it is a monoclonal antibody that is selective. We use the term chemotherapy for drugs that non-specifically kill fast-growing cells. We call Rituxan (rituximab) a biologic therapy, not chemotherapy. Hope that helps! ...Read more

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What is adjuvant chemo?

What is adjuvant chemo?

Adjuvant chemo: Adjuvant chemo is chemotherapy that is given after curative surgical resection of a cancer. It is given to reduce risk of recurrence of cancer. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
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How effective iressa (gefitinib) for lung cancer after chemo?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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Can Taxol (paclitaxel) treat pneumonitis?

Can Taxol (paclitaxel) treat pneumonitis?

No: Taxol (paclitaxel) is a chemotherapeutic agent used to treat malignant, metastatic disease. Pneumonitis is an inflammatory process that needs antibiotics to bring the disease under control. One of the complications of chemo like Taxol (paclitaxel) is suppressing the immune system. As such reports appear that pneumonitis following the use of Taxol (paclitaxel) as in breast cancer occurs following the use of this agent. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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Taxol (paclitaxel) side effects

Taxol (paclitaxel) side effects

Many: The most common side effects are hair loss, lowered blood counts, neuropathy, leg pain, mouth sores, and severe allergic reaction due to the solvent used to dilute Taxol (paclitaxel) (called cremophor). ...Read more

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Why etoposide administered before ifosfamide in chemotherapy ?

Why etoposide administered before ifosfamide in chemotherapy ?

NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

YES DOUBLET: Taxotere (docetaxel) + carboplatin: is a combination regimen used in certain cancers like lung, ovary and breast (with herceptin). ...Read more

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Is the chemo drug docetaxel (taxotere) considered a carboplatin based duplex?

No: Carboplatin and docetaxel (taxotere) are different drugs. They are often used together as part of a "platinum-based doublet" such as in lung cancer chemotherapy. ...Read more

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Can gemcitabine be substituted for taxotere (docetaxel)?

Can gemcitabine be substituted for taxotere (docetaxel)?

Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more

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Is Xeloda (capecitabine) effective for breast cancer?

Is Xeloda (capecitabine) effective for breast cancer?

Xeloda (capecitabine) for breast ca: Xeloda (capecitabine) also known as Capecitabine is a very effective oral chemotherapy drug used for metastatic or stage 4 breast cancer. It can be used by itself (mono therapy) or as part of combination chemotherapy. Major side effects include diarrhea, hand foot syndrome, nausea and small chance of coronary spasm. It is well tolerated. Patients on Xeloda (capecitabine) need to be followed closely by medical oncologists. ...Read more

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How does Taxol (paclitaxel) treat cancer?

How does Taxol (paclitaxel) treat cancer?

Inhibits division: Taxol (paclitaxel) is a chemotherapy drug that inhibits microtubules. This ends up inhibiting cell replication thereby making it difficult for cancer cells to continue dividing. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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Dr. Ana Adelstein
14 doctors shared insights

Topotecan (Definition)

Topotecan hydrochloride is a cancer-related hormone which is a ...Read more


Dr. Andrew Seibert
7 doctors shared insights

Hycamtin (Definition)

Hycamtin is a cancer-related hormone which is a ...Read more