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Doctor insights on: Topamax Topiramate Migraine

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What experience has anyone had with topamax (topiramate) for migraine?

What experience has anyone had with topamax (topiramate) for migraine?

Very effective: Topamax (topiramate) has been very effective for many of my patients. Some patients have complained of cognitive side effects such as speech disturbance and others such as weight loss. ...Read more

Dr. Colin Sanner
401 doctors shared insights

Topiramate (Definition)

Is indicated to treat epilepsy, but mainly a second line or adjunctive agent, and also useful to prevent migraine headaches. Has several adverse effects including: kidney stones, narrow angle glaucoma, metabolic acidosis, heatstroke in kids, paresthesias, slowing of speech and cognition, drowsiness. ...Read more


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I suffer from migraines and pass out. I am on topamax, (topiramate) and migraine medication.... Any recomendations?

Exercise, magnesium: If the MRI and eeg are normal, aerobic exercise, regular low-carb meals, magnesium, coq10, and other supplements can help. Topamax (topiramate) can cause many side effects, including kidney stones in 20%, acidosis with fatigue and malaise, memory difficulties, and many other. Botox is much more effective, much safer, and now is covered by most insurance plans. Read more about alternatives at nyheadache. Com. ...Read more

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My topamax (topiramate) for migraine causes numbness in my feet, what helps?

My topamax (topiramate) for migraine causes numbness in my feet, what helps?

See details: Topamax (topiramate) needs to be taken regularly to help prevent migraines. The numbness is fairly common and can improve or resolve even with continued use of topamax (topiramate). The only other options are to reduce the topamax (topiramate) dose or stop it completely. ...Read more

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I am currently taking topamax (topiramate) for migraine and experiencing cognitive deficits (memory). What are the best alternatives for migraine prophylaxis?

I am currently taking topamax (topiramate) for migraine and experiencing cognitive deficits (memory). What are the best alternatives for migraine prophylaxis?

NOT SURPRISING: Topamax (topiramate) (sometimes known as "dopeamax") very often causes both speech and cognitive issues due to its affect on a short-term memory pathway (perforant pathway, ampa). Would advise considering possibly depakote, or Naproxen (not beta blockers or calcium channel blockers). But how about otc preps such as riboflavin, coq-10, butterbur, feverfew, maybe magnesium, and lastly botox? ...Read more

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I take topamax (topiramate) for migraine prevention, I was told I can't take OTC meds [tylenol etc] for pain whiletaking the topamax (topiramate). Why is that? Thank you.

Medication overuse: If you on a prophylactic med you may be having frequent headaches. Frequent use of otcs can lead to tolerance of medications and rebound or chronic daily headaches. ...Read more

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My Dr put me topamax (topiramate) for migraine. I'm allergic to penicillin and sulfa.drugs. And nsaids drugs cause I have gi problems. Thanks.

So what's your: Question? Topamax (topiramate) isn't related to the other medications you mentioned. Besides, do you really have allergies to those medicines, or just side effects and intolerance, check with the prescribing physician if you have questions, best wishes ...Read more

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Just diagnosed w/thrombocytopenia MPV 10.1fL. I'm on Propranolol & Topamax (topiramate) for migraine. Which is likely cause? If I stop meds will platelets return?

Just diagnosed w/thrombocytopenia MPV 10.1fL. I'm on Propranolol & Topamax (topiramate) for migraine. Which is likely cause? If I stop meds will platelets return?

You must discuss it: Be certain that your Dr(s) know about the drugs you take and urge them to work on the best resolution of this situation. It's way too delicate, complicated and important for you to manage on your own. Their training is for this sort of thing and it's their responsibility to handle it. Be helpful and firm and persistent but trust experts on this. ...Read more

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I take100mg topamax (topiramate) for migraine with 200mg seroquel topamax (topiramate) cuts my appetite when waking up I can't fall asleep easier should I take topamax (topiramate) earlier?

Depends : If topamax (topiramate) is keeping you awake, it certainly can be taken earlier. If your are on seroquel xr, you should take it earlier (by 3-4hours) so it peaks and makes you sleepy at bedtime. If it is regular release, take it 1/2 to 1 hour before bedtime. If you are driving in the evening you should not take your medications until you are ready for bed. If this does not help, consider melatonin. ...Read more

Dr. Brian Le Dr. Le
2 doctors agreed:
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Are there any side effects I can expect taking topamax (topiramate) for migraines?

Dr. Brian Le Dr. Le
2 doctors agreed:

Topamax (topiramate): Topamax (topiramate) has several side effects. The most common side effect is numbness and tingling. Other side effects might include fatigue, taste change, weight loss, difficulty with concentration, difficult with memory, loss appetite, nausea, vomiting, diarrhea .... ...Read more

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Was given topamax (topiramate) for migraines but I've heard/read about the horrible side effects. Are they all true? I'm terrified!

Was given topamax (topiramate) for migraines but I've heard/read about the horrible side effects.  Are they all true?  I'm terrified!

Here is the deal: The drug information that is provided about medication side effects refers to "potential" side effects. It doesn't mean that you will necessarily get any particular side effects. ...Read more

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I take topamax (topiramate) for migraines 2x daily, is it safe to discontinue it suddenly? I lost my insurance & it is to expensive for me to purchase.

I take topamax (topiramate) for migraines 2x daily, is it safe to discontinue it suddenly? I lost my insurance & it is to expensive for me to purchase.

No: With any neurologic medication it is best to taper down the dose instead of stopping it suddenly. By stopping it suddenly you may experience some side effects such as mood disturbances, headaches, insomnia, anxiety. Ask you provider to give you a regimen to come off of it. ...Read more

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On topamax (topiramate) for migraines dr wants to adjust meds 4 concentration issues I've had 1 migraines since oct & lost 50lbs I like this! Is there similar med?

Sort of: There are several meds that can help migraine, but none with the same appetite suppressant effects. But the good news is that the line/dose between cognitive effects and not is often as little as 25 mgs. Therefore, careful downward titration in 25 mg increments every month to 6 weeks might find the golden dose of headache control with clear thinking. ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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What is the normal dose of topamax (topiramate) for migraines?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Topamax (topiramate): For adults & children over 12 years of age, it would be 50mg. Twice daily. ...Read more

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What is the best dosage if topamax (topiramate) for migraines?

See below: Typical dosage for many patients is 50 mg twice daily, but some pts may require more. Key is to take twice daily, and doses up to 200 mg twice daily may be needed, but side effects may limit. Other preventatives are available if problems occur. ...Read more

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Which are the best alternatives for topamax (topiramate)? Treating migraines

Which are the best alternatives for topamax (topiramate)? Treating migraines

See HA specialist: Once a diagnosis of migraine has been made, effective management of migraine involves three specific strategies: 1) patient education, 2) nonpharmacological management, and 3) pharmacological (medical) management. See an orofacial pain or headache specialist for evaluation and professional management. ...Read more

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Is 100mg the highest dose of topamax (topiramate) for migraines and can it be taken with other pills? Also, can you take it once a day or must it be split?

Is 100mg the highest dose of topamax (topiramate) for migraines and can it be taken with other pills? Also, can you take it once a day or must it be split?

Not really: The clinical trial in migraine prevention used 100 mg as the maximal dose. Since the medication is not a delayed release preparation, should be administered twice a day. Increasing the dose can cause further resection in frequency and intensity of migraines, but at the risk of side effects. ...Read more

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I have been on topamax (topiramate) for migraines for 3 months +not helpIng. I'mon 75mg am 75mg pm they are increasing in serverity since going pass 100 mg a day.

I have been on topamax (topiramate) for migraines for 3 months +not helpIng. I'mon 75mg am 75mg pm they are increasing in serverity since going pass 100 mg a day.

Try magnesium: Try mag nesium. The citrate form is easy to find but can cause loose stool. Start with 150 mg when you are not traveling and increase the dose to up to 6/day. If diarrhea occurs try magnesium taurate from lifeextension.org. Get you vitamin d levels to 60-80 and have your dr test the,m. ...Read more

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I take 50mg topamax (topiramate) for migraines & I have problems with loss of appetite. I have not eaten in 3 days. Is this normal?

Expected side effect: I would not say this is normal, but it is a very common side effect of topiramate. You need to speak to your neurologist or whoever is prescribing this, because loss of appetite and long periods of not eating can be doing much more damage than just causing weight loss. Please see your neurologist and ask for a medication change. If change is not option, consider megase or marinol. ...Read more

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I'm taking Trileptal for tinnitus& hyperacusis &recently started Topamax (topiramate) for migraines. Is it true that trileptal reduces amount of topamax (topiramate) in system?

I'm taking Trileptal for tinnitus& hyperacusis &recently started Topamax (topiramate) for migraines. Is it true that trileptal reduces amount of topamax (topiramate) in system?

Possible: Trileptal are Topamax are enzyme inducers, but to a much lesser extent than other AEDs. Using topiramate together with trileptal may increase side effects and can be harmful, but quite rare. ...Read more

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Is it unusual to take topamax (topiramate) for migraines and still have eye pain?

Is it unusual to take topamax (topiramate) for migraines and still have eye pain?

No: Most migraine prophylactic medications do not "cure" migraines. Instead, success is measured in decreased frequency and intensity of the migraines. ...Read more

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If I am on Lamictal for depression and Topamax (topiramate) for migraines will seizure activity still show up on my 24 hr EEG test?

If I am on Lamictal for depression and Topamax (topiramate) for migraines will seizure activity still show up on my 24 hr EEG test?

Explanation: Both Lamictal and Topamax (topiramate) are anti-epileptic drugs, and both could control seizures in an additive fashion. But both have therapeutic ranges, and doses may not be sufficient to control all spells. You doctor obviously feels there may be break-through events that need to be confirmed. The EEG is likely very worthwhile. ...Read more

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Started with twitching eye, then my biceps, now my hand.... Is it cause for alarm? Been off topamax (topiramate) for migraines about a month

Started with twitching eye, then my biceps, now my hand.... Is it cause for alarm? Been off topamax (topiramate) for migraines about a month

Stress and Anxiety: A twitching eye and muscles can be one sign of stress and anxiety. Reducing the cause of the stress can help make the twitching stop. See your PCP for consultation and tests. ...Read more

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Trileptal vs Lamictal vs Topamax (topiramate) for Excitotoxicity, migraine syndrome. I know they work differently but what are upsides to each compared to others?

Trileptal vs Lamictal vs Topamax (topiramate) for Excitotoxicity, migraine syndrome. I know they work differently but what are upsides to each compared to others?

See your doctor: There is no such thing as "best" or "worst" medication, only those that work and don't work, based on the patient's individual circumstances and genetics. See an orofacial pain or headache specialist for evaluation and professional management. ...Read more

Dr. Bennett Machanic
1,496 doctors shared insights

Migraine Headaches (Definition)

Migraine headaches are a common condition that often include a headache with throbbing, pulsing pain, blurriness of vision, nausea, and sensitivity to light. They ...Read more


Dr. Dariush Saghafi
1,882 doctors shared insights

Migraine (Definition)

A type of headache that is associated with throbbing localized pain and usually causes light ...Read more


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