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Doctor insights on: Topamax Pregnant Cause Cleft Lip

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Dr. Chad Levitt
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Which antihypertensive drugs that can cause cleft lip/palate if taken during pregnancy?

Which antihypertensive drugs that can cause cleft lip/palate if taken during pregnancy?

ACEi/ ARBs: Not sure there's a drug that links specifically to cleft lip but it is clear that you should avoid ACE Inhibitors and ARBs during pregnancy due to heart and kidney abnormalities that can occur. ...Read more

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I was wondering if a cleft lip can form after 5 months of pregnancy?

I was wondering if a cleft lip can form after 5 months of pregnancy?

Could find it: The cleft lip would have been present all along but a doctor could find it or see it for the first time at 5 months. ...Read more

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42 with history of 2 children with cleft lip and palate with cerbralpalsy I am pregnant and really worried about it what are my chance of a normal ?

42 with history of 2 children with cleft lip and palate with cerbralpalsy  I am pregnant and really worried about  it what are my chance of a normal ?

Www.cleftline.org.: Or both parents could be carriers of an autosomal recessive disorder, or one parent could have an autosomal dominant disorder with variable expression. If the "cp" is hypotonic (low muscle tone), the children may have a connective tissue disorder.They do need a genetic evaluation. A 2nd-trimester high-resolution fetal ultrasound may show a cleft lip;3-d fus may be needed to see a cleft palate. ...Read more

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What are the odds a baby born with cleft lip/ pallet while taking lamotrigine 50 mg. 6 weeks pregnant. Been on it since mid feb.

What are the odds a baby born with cleft lip/ pallet while taking lamotrigine 50 mg. 6 weeks pregnant. Been on it since mid feb.

Data varies: The data is inconclusive. Multiple studies have investigate this with mixed results. This tells us that there may be a small increase risk but if there is it is very small. The known risk of untreated bipolar disorder or seizure disorder likely outweighs the theoretical risk of medication exposure. ...Read more

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6 weeks pregnant. Been taking lamotrigine 50 mg since mid february. Could my baby already developed a cleft lip/pallate? At this early in pregnancy?

6 weeks pregnant. Been taking lamotrigine 50 mg since mid february. Could my baby already developed a cleft lip/pallate? At this early in pregnancy?

Unlikely: While many anti-epileptic drugs do have an increased risk of birth defects, Lamictal has not yet been shown to have any issues despite extensive testing. Do also keep in mind that seizures themselves are harmful to the fetus, and continuing your medication is critical. I would highly recommend seeing your neurologist on a regular basis during your pregnancy to make sure that blood levels are ok. ...Read more

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What causes children to get a cleft lip or plate?

Different causes: Some cases of cleft lip and palate may be hereditary. Other cases may be spontaneous without any family history. If there is a history of cleft lip or palate in your family then you may want to consult with a genetic counsellor. ...Read more

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I was born with bilateral cleft lip and palate. What caused it?

Unknown: No one really knows why this happens but it is common. Cleft lip and palate appear in one out of 700 live caucasian births in the United States. The clefts can be surgically repaired. ...Read more

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Is a cleft lip and palate caused by mutation, translation, deletion or duplication?

All the above: The genetics for cleft lip and palate is only partially understood. There are a number of genetic mutations (deletions, duplications among them) that can be associated with clefting. There is no single genetic explanation. ...Read more

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Dr. Colin Sanner
373 doctors shared insights

Topiramate (Definition)

Is indicated to treat epilepsy, but mainly a second line or adjunctive agent, and also useful to prevent migraine headaches. Has several adverse effects including: kidney stones, narrow angle glaucoma, metabolic acidosis, heatstroke in kids, paresthesias, slowing of speech and cognition, drowsiness. ...Read more


Dr. Daniel Sampson
202 doctors shared insights

Cleft Palate (Definition)

A congenital fissure in the roof of the mouth, resulting from incomplete fusion of the palate during embryonic development. It may involve only the uvula or extend through the entire ...Read more