Doctor insights on:
Tonsil Cancer Metastasis
I'm concerned I have tonsil cancer. My 1 tonsil has been bigger for 10yrs. ENT said normal asymmetry. Mouth sore same side. Retromolar metastasis? : (
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
What are the possibilities of bone cancer or metastases form throat cancer that had a primary in the left tonsil. Stage 4in tonsil and 3 lymph nodes/?
Unusual: Very unusual to present with bone metastases. Likelihood there is nothing outside the neck. ...Read more
No answer for: This depends. It is different for different people. ...Read more
Tumors can: Go to the lung substance, or to the lining of the chest cavity. As the tumor expands or fluid accumulates, it crowds out the abilty of the lung to do its job, and shortness of breath, oxygen starvation occurs. Removing fluid, and treating with systemic therapy can slow progresson. ...Read more
If you mean a that: Stomach tumor announces itself by an ovarian mass, the answer is yes, even has a name called kruckenberg tumor, but that applies to any tumor travelling to the ovary. ...Read more
I developed a lung metastasis from orihinal rectus cancer treated with chimio radio and asportation. Why this lung metastasis and what s the best t?
Different results: Metastasis arises from primary, the former being clonal and the primary, polyclonal. What spreads to a site such as liver or lung can only grow within that parenchyma and never spread elsewhere. The primary has multiple clones each only capable of spreading to a local site and growing there. Thus primary should always be removed and met focal disease treated later for best survival. ...Read more
Cancer spread.: Metastasis is the spread of cancer from the place that it formed to other organs in the body. This usually is a bad sign prognostically, indicating more aggressive behavior. Some cancers can metastasize early, and others rarely do. The "stage" of cancer is determined by multiple factors, depending on the type of cancer. The presence of metastases often means a higher stage, worse prognosis. ...Read more
Cancer: Your oncologist will discuss with you the treatment options and prognosis. ...Read more
Prostate cancer: The most common metastatic site would be bones-although it also can go to other sites- lymph glands, lung, liver etc. Symptoms will depend on the location of metastases. Bone pain, fractures would be the symptoms of bony mets. If spread to the adjacent area such as bladder area- blood in urine, lower abdomen pain, prob wi/ urination, obstruction can happen. Weight loss, weakness are common too. ...Read more
Mesenteric nodes: As colon cancer grows from premalignant cells in the mucosa of bowel it invades the muscularis reaching serosal outer surface (Dukes B). It then invades nodes of the mesentery C1 expanding to 4 or more nodes C2 and then along the mesenteric lymphatics to liver. Subpopulations in the primary however can eventually spread directly to lung or bone depending on their surface antigens. ...Read more
Many choices: A few options here. For bone involvement a na-f18 pet scan is the most sensitive along with MRI scans. Standard bone scan, imho, is outdated. Also, we find the measurement of ctc's (circulating tumor cells, very useful. Standard ct scan is good for lung and liver disease. Last, MRI with iron nanoparticles is great for lymph node + disease evaluation. Prostatscint is not so useful anymore. ...Read more
Can it be possible for you to live with untreated skin cancer for more than 10 years without having metastasis?
Can you tell me about angiogenesis promoting both the growth of cancers and the metastasis of cancer cells to other sites in the body?
Tumors grow in general in an anaerobic media and require hyperbaric oxygen to destroy. Folkman developed drug angiostatin which failed to prevent cancer spread. Avastin (bevacizumab) which is an anti vegf drug doesn't destroy blood supply. It appears to help by opening microvasculature to tumors to let chemo enter more effectively.
Blood vessels in tumors are the conduit for vessel invasion by tumor cells. ...Read more
If there was an extract that would induce apoptosis/autophagy in cancerous cells and prevent metastasis, would it be beneficial to treating cancers?
Theoretically: Yes substance that would induce programmed cell death would be beneficial, but would need to target only neoplastic cells. ...Read more
Staging: Breast cancer staging is described as t (tumor size), n (lymph node metastases) and m (metastases to sites like bone, lung, etc). In a simplified short answer: stage 0 is non-invasive breast cancer, stage 1 is no spread to lymph nodes, stage 2 and stage 3 has lymph node spread and larger tumors, and stage 4 would have metastases to other organs. ...Read more
It varies: This is often a very difficult, if not impossible, question to answer for patients. Knowing someone's cancer type and stage and overall health, we can look at statistics of comparable patients and provide estimates of response to therapy, but this is, at best, an educated guess. Statistics are for populations, not for individuals--what does someone look like who has "70% survived" a cancer? ...Read more
How is it determined that two cancers in body are a genuine Metastasis case and not two individual cancers?
Cancers: If they are both biopsied, it is easy to tell, by the tissue types. If they are not biopsied, your doctor is most likely going by clinical experience. Good luck. ...Read more
Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?
Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more
What is the life expectancy of a cancer patient? Has there any case where prostate metastasis could lead man to live more then 10 years?
Yes: There is no one answer for life expectancy of a cancer patient. Patients with metastatic prostate cancer can live for many years, typically with ongoing hormonal therapy. At some point the cancer generally becomes resistant to hormonal therapy and there are then additional systemic treatments that can further prolong life. 10 years is longer than most, but not impossible. ...Read more
The question is: A puzzle. Are you asking: what next, in someone with lung and brain disease? (usually starting in lung, then going to brain). Or the pattern of metastasis if either is primary: brain as primary almost never metastasizes outsie cns, whereas lung commonly foes to brain, as well as other lung, liver, bones, adrenals. ...Read more
A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more