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Doctor insights on: Tocolytics

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Dr. Andrew Seibert
4 doctors shared insights

Tocolytics (Overview)

Tocolytics are medications that stop uterine contractions. The most frequently used are nifedipine, terbutaline, magnesium, and indomethacin.


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Nifedipine for preterm labor risks?

Nifedipine for preterm labor risks?

Much safer: Nifedipine (brand name: procardia) is a much safer class of medication for premature labor than it's predecessors, such as terbutaline or ritodrine, which could cause fast heartbeat, high blood sugars, and even pulmonary edema. ...Read more

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Dr. Andrew Seibert
4 doctors shared insights

Tocolytics (Overview)

Tocolytics are medications that stop uterine contractions. The most frequently used are nifedipine, terbutaline, magnesium, and indomethacin.


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Are there specific harmful effects of tocolytic therapy?

Are there specific harmful effects of tocolytic therapy?

Yes: Tocolytics are drugs that are used to stop preterm labor. Terbutaline when used long-term can cause increased risk of heart attack and stroke in the mother. Magnesium can cause some muscle weakening in both mother and baby but may have a protective effect on the baby's brain. Indocin (indomethacin) can cause decreased amniotic fluid and premature changes in the blood flow through the baby's lungs. ...Read more

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Preparing for Labor and Delivery (Checklist)

Watch for signs of labor, such as increasing contractions or fluid leakages
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If the baby is not moving, do kick counts, and keep in mind that you should feel 10 in two hours
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Call your doctor with any questions or concerns
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Uses of tocolytics and oxytocic drugs?

Uses of tocolytics and oxytocic drugs?

Too ,long to answer: Here please discuss with yoru obgyn as i discuss with any of my pts in coral springs and boca raton who may need these medications during their pregnancy and or labor, the idea is to prevent premature labor rather than have to treat it and oxytocin is very safe if used and monitored , I use it frequently for induction and augmenation of labor and it has prevented many csections. ...Read more

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Procardia (nifedipine) ok to stop preterm contractions?

Procardia (nifedipine) ok to stop preterm contractions?

Preterm contractions: Premature contractions? Or premature labor? Premature labor is treated with Nifedipine (procardia). Real premature labor can't really be stopped by any agent for more than 24 - 48 hrs. Enough time to give steroids to the mother to accelerate fetal lung maturity. ...Read more

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Can prenatal massage therapists induce labor?

Can prenatal massage therapists induce labor?

OMM: Osteopathic manipulation, particularly at the junction of the thoracic and lumbar spine, can be very effective in inducing labor when carefully applied by a skilled physician. The physician can also help to deliver the baby if things start moving quickly. ...Read more

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Effectiveness of cervadil vs pitocin (oxytocin) induction?

Effectiveness of cervadil vs pitocin (oxytocin) induction?

Depends on cervix: Before induction your current cervical exam is used as a determinant for which mode of induction. Cervidil is most likely used when the cervix is less soft, dilated, and effaced (thinned out), and more posterior, as it increases prostaglandins release to stimulate dilation, thinning and softening. Those who are already dilated and effaced benefit more from pitocin (oxytocin). ...Read more

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Nifedipine used for labor?

Nifedipine used for labor?

Used to stop labor: Nifedipine can be used to stop threated preterm labor in certain circumstances. ...Read more

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Terbutaline used to stopped contractions?

Terbutaline  used to stopped contractions?

Yes: Terbutaline can be used to stop contractions, but it is not terribly effective, and has some significant side effects so it is not being used very much anymore. ...Read more

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Are there specific harmful effects of tocolytic therapy?

Yes: Tocolytics are drugs that are used to stop preterm labor. Terbutaline when used long-term can cause increased risk of heart attack and stroke in the mother. Magnesium can cause some muscle weakening in both mother and baby but may have a protective effect on the baby's brain. Indocin (indomethacin) can cause decreased amniotic fluid and premature changes in the blood flow through the baby's lungs. ...Read more

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Can mag withdrawal cause preterm labor?

Can mag withdrawal cause preterm labor?

Preterm labor: Premature labor is caused by inflammation or infection. Magnesium has been used for the treatment of premature labor, but multiple studies have shown that it doesn't really stop contractions. Its use for this indication is declining. Withdrawing an ineffective medication can't cause premature labor. ...Read more

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Uses of tocolytics and oxytocic drugs?

Too ,long to answer: Here please discuss with yoru obgyn as i discuss with any of my pts in coral springs and boca raton who may need these medications during their pregnancy and or labor, the idea is to prevent premature labor rather than have to treat it and oxytocin is very safe if used and monitored , I use it frequently for induction and augmenation of labor and it has prevented many csections. ...Read more

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How dangerous are labor epidurals?

How dangerous are labor epidurals?

Depends.: As far as the mother is concerned, pretty safe in good hands, other than a remote risk of chronic low back pain. As far as the fetus is concerned, early epidurals are associated with increased occiput posterior and cesarean sections, fever in labor and sepsis work-up in the nursery. Of course, the alternative (intravenous narcotics) is even worse for the fetus! ...Read more

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Are deliveries by midwifes safe?

Are deliveries by midwifes safe?

THAT DEPENDS: On the training and your stituation and if the midwife delivers in the hospital and has the proper backup provided by a board certified obgyn who can respond quickly in an emergency situation. I have worked with some very good midwives and shortly with some bad ones. My patients go to me because I do all of my own deliveries and they know that I am trained to take care of a problem. ...Read more

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How are thrombolytic drugs administered?

How are thrombolytic drugs administered?

Usually iv: Usually from a peripheral iv. Sometimes can be given directly into artery with a catheter. ...Read more

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Are progesterone shows good for preterm labor?

Are progesterone shows good for preterm labor?

Yes: In a select group of patients , those with a single fetus, and prior preterm delivery, have benefitted from taking a specific kind of progesterone. ...Read more

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Are aggrenox and heparin given together?

Are aggrenox and heparin given together?

Possibly: They can be - it depends on the indication. The risk of bleeding will be increased but the risk of clotting will be lowered. It's a judgement call. That why doctors need a lot training. ...Read more

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Why isn't terbutaline approved by the fda for preterm labor?

Side effect profile.: Terbutaline can block the uterine contractions of the final common pathway leading to preterm labor, however it does nothing to address the etiology of preterm contractions and has significant and potentially life-threatening maternal side effects with tachycardia, hyperglycemia and arrhythmias. There is little evidence that terbutaline (a brochodilator by design) is useful for long-term tocolysis. ...Read more

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Dr. Amrita Dosanjh
2 doctors shared insights

Labor Stopping Drug (Definition)

Labor stopping agents are a kind of women's ...Read more