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Doctor insights on: Tnm Staging Breast Cancer

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Describe breast cancer staging according tnm?

Describe breast cancer staging according tnm?

Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read more

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Dr. Barry Rosen
1,336 doctors shared insights

Breast Cancer (Female) (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more


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Breast cancer staging according TNM means what?

Breast cancer staging according TNM means what?

TNM breast cancer: Tnm is one of the staging system commonly used for cancer. It stands for t-tumor ( the size of the tumor- the bigger is the tumor the higher is the stage) ; n- nodal status ( involvement to the lymph glands) - and m- presence of metastatic disease to the distant organ. See more here: http://cancer.Gov/cancertopics/wyntk/breast/page7. ...Read more

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What is the definition or description of: pet-ct breast cancer staging?

What is the definition or description of: pet-ct breast cancer staging?

PET - CT: Pet-ct scans are a means of combining the x-ray of a ct scan with the functional study of a pet scan. The pet scan can see over-active cells that are actively using glucose. The over-active cells may represent cancer cells and is a means of telling if cancer cells are spreading or growing somewhere in the body. The ct scan may see a growth & the pet scan can see if the growth has overactive cells. ...Read more

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How common is breast cancer?

How common is breast cancer?

Pretty common : Estimated new cases and deaths from breast cancer in the United States in 2012: new cases: 226, 870 (female); 2, 190 (male) and 39, 510 (female); 410 (male) deaths. Lifetime risk is 1 to 8. Risk is higher with the increased of age. ...Read more

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How can breast cancer spread?

How can breast cancer spread?

3 ways: It spread through lymphatic organ ( lymph glands) , through blood circulation and direct invasion to the adjacent organ such as skin, chest wall etc. ...Read more

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How does breast cancer spread?

How does breast cancer spread?

3 Basic Ways: Breast cancer can spread in 3 basic ways - it can grow larger and larger, invading into the skin or muscle; it can invade into the blood vessels and then travel to other areas of the body (most commonly liver, lungs, bone and brain), and it can invade into the lymphatic vessels and travel to the lymph nodes under the arm and other areas of the body. ...Read more

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How can breast cancer develop?

One mutant cell: One normal cell inside your breast mutates (becomes abnormal), and begins to grow. The normal "stop" signal that tell a cell to stop dividing doesn't work, so the cells keep dividing. One cell becomes two, two become four, four become eight, etc. It takes millions of cancer cells to form a tumor you can feel. ...Read more

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How does breast cancer develop?

How does breast cancer develop?

One mutant cell: One normal cell inside your breast mutates (becomes abnormal), and begins to grow. The normal "stop" signal that tell a cell to stop dividing doesn't work, so the cells keep dividing. One cell becomes two, two become four, four become eight, etc. It takes millions of cancer cells to form a tumor you can feel. ...Read more

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Whom does breast cancer affect?

Whom does breast cancer affect?

One-In-Eight Women: A common misconception is that women without a family history need not worry about breast cancer. In truth, most breast cancers occur in women with no risk factors. Furthermore, the incidence increases with age. Every woman needs to have regular screening mammograms beginning at age 40. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Staging (Definition)

Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more