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Doctor insights on: Tnm Staging Breast Cancer

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Describe breast cancer staging according tnm?

Describe breast cancer staging according tnm?

Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read more

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Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Breast cancer staging according TNM means what?

Breast cancer staging according TNM means what?

TNM breast cancer: Tnm is one of the staging system commonly used for cancer. It stands for t-tumor ( the size of the tumor- the bigger is the tumor the higher is the stage) ; n- nodal status ( involvement to the lymph glands) - and m- presence of metastatic disease to the distant organ. See more here: http://cancer.Gov/cancertopics/wyntk/breast/page7. ...Read more

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Prognosis stage 3 breast cancer?

Prognosis stage 3 breast cancer?

Curable!: Stage 3 means the tumor is large and/or the cancer has spread to many lymph nodes. It can still be cured with a combination of surgery, chemotherapy and radiation therapy. The risk of cancer returning depends on many factors-- age, # of involved lymph nodes, and whether the cancer has hormone receptors or her2. About 50% of stage 3 breast cancer patients are cured. Have hope! ...Read more

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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How is stage IV breast cancer different from stage III breast cancer?

How is stage IV breast cancer different from stage III breast cancer?

Location: In stage iii, the cancer still hasn't spread far beyond the breast and nearby lymph nodes. However, in this stage there typically are many lymph nodes involved or the tumor is so large it extends to the chest wall or involves the skin of the breast. stage IV breast cancer has spread to distant sites of the body. ...Read more

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What is metastatic breast cancer?

What is metastatic breast cancer?

Spread : This means that the cancer has spread to other areas outside of the breast. This is known as stage 4. With the use of modern chemotherapy, this disease can be controlled. I recommend you meet with your medical oncologist to determine options available for treatment. ...Read more

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What is breast cancer sentinel node micro metastases?

What is breast cancer sentinel node micro metastases?

Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read more

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Is stage 3c breast cancer curable?

Is stage 3c breast cancer curable?

Yes: ...In theory, with aggressive multi modality therapy (surgery plus chemo plus radiation +/- hormones +/- herceptin). The risk of relapse is high but you do all you can and hope for the best. If this is about you, fight well and best wishes. ...Read more

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What are the survival statistics for breast cancer invasive ductal carcinoma?

What are the survival statistics for breast cancer invasive ductal carcinoma?

It depends on many f: Most women with localized breast cancer do very well and there is high cure rate. Overall 75%-80% of breast cancers are curable. But you need to know what stage of cancer it is? You should also know what subtype(there are 3 different types) of breast cancer it is. Further there is the matter of what type of adjuvant therapy(post surgery treatment) was used. I'am sure your oncologist can answeryr. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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Chemotherapy hormone receptor positive node breast cancer?

Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Whats the classification of breast cancer metastasis?

Whats the classification of breast cancer metastasis?

Staging: Breast cancer staging is described as t (tumor size), n (lymph node metastases) and m (metastases to sites like bone, lung, etc). In a simplified short answer: stage 0 is non-invasive breast cancer, stage 1 is no spread to lymph nodes, stage 2 and stage 3 has lymph node spread and larger tumors, and stage 4 would have metastases to other organs. ...Read more

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Is stage two breast cancer curable?

Is stage two breast cancer curable?

Survival Rates: According to the american cancer society the 5 year relative survival rate for stage 1 is 100%, stage ii- 93%, stage iii is 72% and stage IV is 22%. ...Read more

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Breast cancer prevention?

Breast cancer prevention?

5 steps: 1. Maintain a healthy weight. Obesity increases your risk of breast cancer 2. Have babies and breast feed. These decrease your risk 3. Limit hormone therapy after menopause. 4. Decrease alcohol intake 5. Exercise - women who have regular physical exercise have a decreased risk of breast cancer. ...Read more

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Abdominal carcinamatosis from breast cancer metastasis?

Abdominal carcinamatosis from breast cancer metastasis?

Could Be: You have a known breast ca? Any other mets? Typically, one would expect mets to bone before abdomen. If pathology on both sites is the same then probably mets. If not, possible second primary (like ovary). Good luck. ...Read more

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Metastatic breast cancer usually spread to liver?

It may: Breast cancer can metastascise to many organs. Regionally to the lymph nodes and distantly to other organs. More commonly to the bones, lung, liver, brain and other visceral structures in the abdomen or pelvis. ...Read more

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Survival various types breast cancer?

Varies: Survival depends on many factors, such as overall health, age, stage of disease and response to treatment. Additional information may be found at www.Cancer.Org. ...Read more

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What is metastatic breast carcinoma?

What is metastatic breast carcinoma?

Cancer 'elsewhere': Metastatic cancer is cancer that has spread from its organ of origin to another part of the body. For example, the most common sites of metastases for breast cancer are the lungs, liver, and bone. Most breast cancers, when caught early and treated in a timely manner, do not ever spread to other organs. ...Read more

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Dr. Barry Rosen
1,378 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Staging (Definition)

Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more