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Doctor insights on: Tnf Inhibitors Food And Drug Administration

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How effective are TNF inhibitors for treating ankylosing spondylitis?

How effective are TNF inhibitors for treating ankylosing spondylitis?

TNF inhibitors: Tumour necrosis factor (TNF)-blocking therapy has been used successfully in the treatment of ankylosing spondylitis. ...Read more

Dr. Heidi Fowler
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What is the mean onset of action and peak time for therapeutic effects to relieve symptoms of RA with tnf inhibitors?

What is the mean onset of action and peak time for therapeutic effects to relieve symptoms of RA with tnf inhibitors?

Several months!: Results can occur quickly, but most say results can take several months to be fully realized. Remember, inflamed tissue within joints can take time to be resorbed! it also depends on the length of time you have had your rheumatoid arthritis, and also whether mechanical damage has occurred! ...Read more

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With other tnf inhibitors such as humira and enbrel (etanercept) are there?

With other tnf inhibitors such as humira and enbrel (etanercept) are there?

See below: Cimzia (certolizumab pegol), simponi (golimumab), and Remicade (infliximab) are the other tnf Alpha inhibitors available in the United States. ...Read more

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What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more

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Which tnf inhibitor for RA has the least GI side effects?

Which tnf inhibitor for RA has the least GI side effects?

Very few for all.: My experience and the published literature on comparative side-effects say they are about the same and not very common. My bias is for Humira and against remicade (infliximab). As far as response and efficacy, most recent studies say that they are equivalant in rheumatoid arthritis. ...Read more

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I'm just started wellbutrin (bupropion) for depression, but I just read it is a tnf inhibitor and can increase the risk of cancer? Is this true?

I'm just started wellbutrin (bupropion) for depression, but I just read it is a tnf inhibitor and can increase the risk of cancer? Is this true?

Comments: Am totally unaware that Wellbutrin (bupropion) has any history of either increasing cancer risk or causing any neoplastic problem in any bodily area. If this were true, would have been removed from market years ago. ...Read more

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Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?

See below: They run about 4figures/month.---if you have not insurance, you may qualify to receive the drug for free directly from the pharmaceutical company. Talk to your rheumatologist about this. ...Read more

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Will tnf-alpha inhibitor work against boneloss?

Will tnf-alpha inhibitor work against boneloss?

In rheum. arthritis?: Osteoporosis is a known complication of rheumatoid arthritis (ra). The bone loss is related to features of the patient (usually a postmenopausal woman), corticosteroid therapy, and the underlying arthritis disease. May have a beneficial effect on bone loss through the medication's strong anti-inflammatory effect. ...Read more